Reprogramming: A New Era in Regenerative Medicine

[1]  I. Wilmut,et al.  "Viable Offspring Derived from Fetal and Adult Mammalian Cells" (1997), by Ian Wilmut et al. , 2014 .

[2]  S. Angulo,et al.  RETRACTED: Directed Conversion of Alzheimer's Disease Patient Skin Fibroblasts into Functional Neurons , 2011, Cell.

[3]  Mitsugu Sekimoto,et al.  Reprogramming of mouse and human cells to pluripotency using mature microRNAs. , 2011, Cell stem cell.

[4]  K. Plath,et al.  Small RNAs loom large during reprogramming. , 2011, Cell stem cell.

[5]  R. Gregory,et al.  MicroRNAs and reprogramming , 2011, Nature Biotechnology.

[6]  S. Lipton,et al.  Direct reprogramming of mouse fibroblasts to neural progenitors , 2011, Proceedings of the National Academy of Sciences.

[7]  J. I. Izpisúa Belmonte,et al.  iPSCs: induced back to controversy. , 2011, Cell stem cell.

[8]  Mudit Gupta,et al.  Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency. , 2011, Cell stem cell.

[9]  R. Stewart,et al.  Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells , 2011, Nature.

[10]  N. Geijsen,et al.  Different flavors of pluripotency, molecular mechanisms, and practical implications. , 2010, Cell stem cell.

[11]  Krishanu Saha,et al.  Pluripotency and Cellular Reprogramming: Facts, Hypotheses, Unresolved Issues , 2010, Cell.

[12]  K. Hochedlinger,et al.  Induced pluripotency: history, mechanisms, and applications. , 2010, Genes & development.

[13]  J. Sandoval,et al.  Epigenetic Modifiers Are Necessary but Not Sufficient for Reprogramming Non-Myelinating Cells into Myelin Gene-Expressing Cells , 2010, PloS one.

[14]  Aaron M. Newman,et al.  Lab-specific gene expression signatures in pluripotent stem cells. , 2010, Cell stem cell.

[15]  M. Pellegrini,et al.  Molecular analyses of human induced pluripotent stem cells and embryonic stem cells. , 2010, Cell stem cell.

[16]  Richard A Young,et al.  Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells. , 2010, Cell stem cell.

[17]  K. Hochedlinger,et al.  Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells , 2010, Nature Biotechnology.

[18]  K. Shiota,et al.  Correction for Seki et al., TIF1β regulates the pluripotency of embryonic stem cells in a phosphorylation-dependent manner , 2010, Proceedings of the National Academy of Sciences.

[19]  R. Jaenisch,et al.  Reprogramming of human peripheral blood cells to induced pluripotent stem cells. , 2010, Cell stem cell.

[20]  M. Araúzo-Bravo,et al.  Human adult germline stem cells in question , 2010, Nature.

[21]  H. Blau,et al.  Nuclear reprogramming to a pluripotent state by three approaches , 2010, Nature.

[22]  Tomohiro Kono,et al.  Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells , 2010, Nature.

[23]  C. Lengner,et al.  Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs , 2010, Proceedings of the National Academy of Sciences.

[24]  Jennifer A. Erwin,et al.  Derivation of Pre-X Inactivation Human Embryonic Stem Cells under Physiological Oxygen Concentrations , 2010, Cell.

[25]  A. Kriegstein,et al.  Regenerative medicine: Cell reprogramming gets direct , 2010, Nature.

[26]  Thomas Vierbuchen,et al.  Direct conversion of fibroblasts to functional neurons by defined factors , 2010, Nature.

[27]  D. Hwang,et al.  Human ES and iPS cells as cell sources for the treatment of Parkinson's disease: Current state and problems , 2009, Journal of cellular biochemistry.

[28]  T. Enver,et al.  Forcing cells to change lineages , 2009, Nature.

[29]  Jeroen S. van Zon,et al.  Direct cell reprogramming is a stochastic process amenable to acceleration , 2009, Nature.

[30]  Fred H. Gage,et al.  Transcriptional Signature and Memory Retention of Human-Induced Pluripotent Stem Cells , 2009, PloS one.

[31]  Laura Clarke,et al.  A safer stem cell: inducing pluripotency , 2009, Nature Medicine.

[32]  Shinya Yamanaka,et al.  Elite and stochastic models for induced pluripotent stem cell generation , 2009, Nature.

[33]  Mike J. Mason,et al.  Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. , 2009, Cell stem cell.

[34]  A. Consiglio,et al.  Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells , 2009, Nature.

[35]  A. B. Evercooren,et al.  In search of human oligodendroglia for myelin repair , 2009, Neuroscience Letters.

[36]  J. Nichols,et al.  Naive and primed pluripotent states. , 2009, Cell stem cell.

[37]  Hans R Schöler,et al.  Regulatory circuits underlying pluripotency and reprogramming. , 2009, Trends in pharmacological sciences.

[38]  Wei Wang,et al.  piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells , 2009, Nature.

[39]  B. Lowry.  Faculty Opinions recommendation of Human induced pluripotent stem cells free of vector and transgene sequences. , 2009 .

[40]  Rudolf Jaenisch,et al.  Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors , 2009, Cell.

[41]  K. Woltjen,et al.  Virus free induction of pluripotency and subsequent excision of reprogramming factors , 2009, Nature.

[42]  Marcos J. Araúzo-Bravo,et al.  Oct4-Induced Pluripotency in Adult Neural Stem Cells , 2009, Cell.

[43]  Alexander Meissner,et al.  Induced pluripotent stem cells: current progress and potential for regenerative medicine. , 2009, Trends in molecular medicine.

[44]  I. Grivennikov.  Embryonic stem cells and the problem of directed differentiation , 2008, Biochemistry (Moscow).

[45]  M. Bonin,et al.  Generation of pluripotent stem cells from adult human testis , 2008, Nature.

[46]  Shinya Yamanaka,et al.  Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors , 2008, Science.

[47]  J. Utikal,et al.  Induced Pluripotent Stem Cells Generated Without Viral Integration , 2008, Science.

[48]  Douglas A. Melton,et al.  In vivo reprogramming of adult pancreatic exocrine cells to β-cells , 2008, Nature.

[49]  Marius Wernig,et al.  A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types , 2008, Nature Biotechnology.

[50]  T. Mikkelsen,et al.  Dissecting direct reprogramming through integrative genomic analysis , 2008, Nature.

[51]  Wenjun Guo,et al.  Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds , 2008, Nature Biotechnology.

[52]  A. Trounson,et al.  Genetic modification of human embryonic stem cells for derivation of target cells. , 2008, Cell stem cell.

[53]  Su-Chun Zhang,et al.  Directed Differentiation of Ventral Spinal Progenitors and Motor Neurons from Human Embryonic Stem Cells by Small Molecules , 2008, Stem cells.

[54]  Jin Woo Chang,et al.  Highly efficient and large-scale generation of functional dopamine neurons from human embryonic stem cells , 2008, Proceedings of the National Academy of Sciences.

[55]  R. Young,et al.  Stem Cells, the Molecular Circuitry of Pluripotency and Nuclear Reprogramming , 2008, Cell.

[56]  George Q. Daley,et al.  Reprogramming of human somatic cells to pluripotency with defined factors , 2008, Nature.

[57]  Xuejin Chen,et al.  An improved protocol that induces human embryonic stem cells to differentiate into neural cells in vitro , 2008, Cell biology international.

[58]  Marius Wernig,et al.  Treatment of Sickle Cell Anemia Mouse Model with iPS Cells Generated from Autologous Skin , 2007, Science.

[59]  Shulan Tian,et al.  Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells , 2007, Science.

[60]  T. Ichisaka,et al.  Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors , 2007, Cell.

[61]  V. Rafuse,et al.  Easy and Rapid Differentiation of Embryonic Stem Cells into Functional Motoneurons Using Sonic Hedgehog‐Producing Cells , 2007, Stem cells.

[62]  Kevin Eggan,et al.  Developmental reprogramming after chromosome transfer into mitotic mouse zygotes , 2007, Nature.

[63]  M. Mattson,et al.  Stage-dependent Olig2 expression in motor neurons and oligodendrocytes differentiated from embryonic stem cells. , 2007, Stem cells and development.

[64]  J. Itskovitz‐Eldor,et al.  Human oligodendrocytes derived from embryonic stem cells: Effect of noggin on phenotypic differentiation in vitro and on myelination in vivo , 2007, Molecular and Cellular Neuroscience.

[65]  L. Iacovitti,et al.  A protocol for the differentiation of human embryonic stem cells into dopaminergic neurons using only chemically defined human additives: Studies in vitro and in vivo , 2007, Brain Research.

[66]  S. Yamanaka,et al.  Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors , 2006, Cell.

[67]  Rudolf Jaenisch,et al.  Nuclear reprogramming and pluripotency , 2006, Nature.

[68]  Gail Mandel,et al.  Reciprocal actions of REST and a microRNA promote neuronal identity , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[69]  H. Miyoshi,et al.  Generation of Cloned Mice by Direct Nuclear Transfer from Natural Killer T Cells , 2005, Current Biology.

[70]  M. Carpenter,et al.  Human embryonic stem cells differentiate into oligodendrocytes in high purity and myelinate after spinal cord transplantation , 2005, Glia.

[71]  A. Kriegstein,et al.  Cortical neurons arise in symmetric and asymmetric division zones and migrate through specific phases , 2004, Nature Neuroscience.

[72]  S. Fujita.  The discovery of the matrix cell, the identification of the multipotent neural stem cell and the development of the central nervous system. , 2003, Cell structure and function.

[73]  H. Son,et al.  Neurons and astrocytes secrete factors that cause stem cells to differentiate into neurons and astrocytes, respectively , 2003, Molecular and Cellular Neuroscience.

[74]  Marius Wernig,et al.  In vitro differentiation of transplantable neural precursors from human embryonic stem cells , 2001, Nature Biotechnology.

[75]  B. Barres,et al.  Induction of Astrocyte Differentiation by Endothelial Cells , 2001, The Journal of Neuroscience.

[76]  S. Goderie,et al.  Timing of CNS Cell Generation A Programmed Sequence of Neuron and Glial Cell Production from Isolated Murine Cortical Stem Cells , 2000, Neuron.

[77]  K. Nakashima,et al.  Astrocyte differentiation mediated by LIF in cooperation with BMP2 , 1999, FEBS letters.

[78]  M. Surani,et al.  Embryonic germ cells induce epigenetic reprogramming of somatic nucleus in hybrid cells , 1997, The EMBO journal.

[79]  H. Blau,et al.  Cytoplasmic activation of human nuclear genes in stable heterocaryons , 1983, Cell.

[80]  S. Kelly.  Studies of the developmental potential of 4- and 8-cell stage mouse blastomeres. , 1977, The Journal of experimental zoology.

[81]  J. Gurdon,et al.  The developmental capacity of nuclei taken from intestinal epithelium cells of feeding tadpoles. , 1962, Journal of embryology and experimental morphology.

[82]  R. Briggs,et al.  Transplantation of Living Nuclei From Blastula Cells into Enucleated Frogs' Eggs. , 1952, Proceedings of the National Academy of Sciences of the United States of America.

[83]  Takashi Aoi,et al.  Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts , 2008, Nature Biotechnology.

[84]  S. Fujita.  Transitory differentiation of matrix cells and its functional role in the morphogenesis of the developing vertebrate CNS. , 1986, Current topics in developmental biology.

[85]  Brief Report Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins , 2022 .