Comparison of two scaling approaches for the development of biomechanical multi-body human models

Dimensional scaling approaches are widely used to develop multi-body human models in injury biomechanics research. Given the limited experimental data for any particular anthropometry, a validated model can be scaled to different sizes to reflect the biological variance of population and used to characterize the human response. This paper compares two scaling approaches at the whole-body level: one is the conventional mass-based scaling approach which assumes geometric similarity; the other is the structure-based approach which assumes additional structural similarity by using idealized mechanical models to account for the specific anatomy and expected loading conditions. Given the use of exterior body dimensions and a uniform Young’s modulus, the two approaches showed close values of the scaling factors for most body regions, with 1.5 % difference on force scaling factors and 13.5 % difference on moment scaling factors, on average. One exception was on the thoracic modeling, with 19.3 % difference on the scaling factor of the deflection. Two 6-year-old child models were generated from a baseline adult model as application example and were evaluated using recent biomechanical data from cadaveric pediatric experiments. The scaled models predicted similar impact responses of the thorax and lower extremity, which were within the experimental corridors; and suggested further consideration of age-specific structural change of the pelvis. Towards improved scaling methods to develop biofidelic human models, this comparative analysis suggests further investigation on interior anatomical geometry and detailed biological material properties associated with the demographic range of the population.

[1]  Lex van Rooij,et al.  Scalability of human models , 2007 .

[2]  T. Rantalainen,et al.  Direction-Specific Diaphyseal Geometry and Mineral Mass Distribution of Tibia and Fibula: A pQCT Study of Female Athletes Representing Different Exercise Loading Types , 2010, Calcified Tissue International.

[3]  G. Zhang,et al.  Evaluating the viscoelastic properties of biological tissues in a new way. , 2005, Journal of musculoskeletal & neuronal interactions.

[4]  H J Mertz,et al.  The Hybrid III 10-Year-Old Dummy. , 2001, Stapp car crash journal.

[5]  Zhao Wei-dong,et al.  Biomechanical character of extremity long bones in children and its significance , 2003 .

[6]  Edward S. Taylor,et al.  Dimensional analysis for engineers , 1974 .

[7]  K. Johnson Contact Mechanics: Frontmatter , 1985 .

[8]  Jason R. Kerrigan,et al.  Design of a Full-Scale Impact System for Analysis of Vehicle Pedestrian Collisions , 2005 .

[9]  Jeff R Crandall,et al.  A New Approach to Multibody Model Development: Pedestrian Lower Extremity , 2009, Traffic injury prevention.

[10]  Harold J. Mertz,et al.  Biomechanical basis for the CRABI and Hybrid III child dummies , 1997 .

[11]  Jason R. Kerrigan,et al.  Dynamic Response Corridors and Injury Thresholds of the Pedestrian Lower Extremities , 2004 .

[12]  Jeffrey Richard Crandall,et al.  Child human model development: a hybrid validation approach , 2008 .

[13]  R. Cook,et al.  Advanced Mechanics of Materials , 1985 .

[14]  J R Crandall,et al.  Comparison of Hybrid III Child Test Dummies to Pediatric PMHS in Blunt Thoracic Impact Response , 2010, Traffic injury prevention.

[15]  David Karasik,et al.  Bone geometry and skeletal fragility , 2006, Current osteoporosis reports.

[16]  D C Viano,et al.  Biomechanics of the human chest, abdomen, and pelvis in lateral impact. , 1989, Accident; analysis and prevention.

[17]  Miguel T. Silva,et al.  Biomechanical Model with Joint Resistance for Impact Simulation , 1997 .

[18]  Harold J. Mertz,et al.  Size, Weight and Biomechanical Impact Response Requirements for Adult Size Small Female and Large Male Dummies , 1989 .

[19]  H. Langhaar Dimensional analysis and theory of models , 1951 .

[20]  Riender Happee,et al.  SCALING OF ADULT TO CHILD RESPONSES APPLIED TO THE THORAX , 1994 .

[21]  M. Holtrop The ultrastructure of bone. , 1975, Annals of clinical and laboratory science.

[22]  Jason R. Kerrigan,et al.  Dynamic Response Corridors of the Human Thigh and Leg in Non-Midpoint Three-Point Bending , 2005 .

[23]  Tsuyoshi Yasuki Mechanism analysis of pedestrian knee-bending angle by sedan-type vehicle using human FE model , 2007 .

[24]  Taewung Kim,et al.  Evaluation of the Biofidelity of Multibody Paediatric Human Models under Component‐level, Blunt Impact and Belt Loading Conditions , 2015 .

[25]  Jun Ouyang,et al.  Thoracic impact testing of pediatric cadaveric subjects. , 2006, The Journal of trauma.

[26]  John W. Melvin,et al.  Injury Assessment Reference Values for the CRABI 6-Month Infant Dummy in a Rear-Facing Infant Restraint with Airbag Deployment , 1995 .

[27]  Jeffrey Richard Crandall,et al.  Pediatric Injury Biomechanics , 2013, Springer New York.

[28]  Rolf H. Eppinger,et al.  Development of dummy and injury index for NHTSA's thoracic side impact protection research program , 1984 .

[29]  Claude Tarriere,et al.  Children are not miniature adults , 1995 .

[30]  Claire C. Gordon,et al.  2012 Anthropometric Survey of U.S. Army Personnel: Methods and Summary Statistics , 2014 .

[31]  François Bermond,et al.  THORACIC AND PELVIS HUMAN RESPONSE TO IMPACT , 1995 .

[32]  Harold J. Mertz,et al.  A procedure for normalizing impact response data , 1984 .

[33]  Riender Happee,et al.  A mathematical human body model for frontal and rearward seated automotive impact loading , 1998 .

[34]  J. Forman,et al.  Human surrogates for injury biomechanics research , 2011, Clinical anatomy.

[35]  D F Huelke,et al.  Infants and children in the adult world of automobile safety design: pediatric and anatomical considerations for design of child restraints. , 1969, Journal of biomechanics.

[36]  Wei-dong Zhao,et al.  Experimental cadaveric study of lateral impact of the pelvis in children. , 2003, Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA.

[37]  Jeffrey Richard Crandall,et al.  DEVELOPMENT OF A DYNAMIC MULTIBODY MODEL TO ANALYZE HUMAN LOWER EXTREMITY IMPACT RESPONSE AND INJURY , 1998 .