Cutaneous manifestations as a clue to the diagnosis of POEMS syndrome

Dermatology consultation was sought for a middle-aged man with multiple asymptomatic skin nodules all over the body. The patient was admitted with neurology inpatient services for altered sensorium and loss of vision for the last 2 days. He also suffered from hyperaesthesia and weakness of limbs for the last 2 years. On physical examination, hepatosplenomegaly was also detected along with neurological and visual abnormalities. Multiple cutaneous erythematous to skin-coloured, dome-shaped, exophytic, sessile as well as pedunculated, soft to firm asymptomatic nodules were observed on trunk, limbs and scalp (figure …