Exploring the potential anti-Alzheimer disease mechanisms of Alpiniae Oxyphyliae Fructus by network pharmacology study and molecular docking

[1]  Yingying Pan,et al.  Progress and Prospects of Research Ideas and Methods in the Network Pharmacology of Traditional Chinese Medicine. , 2022, Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques.

[2]  P. Gold,et al.  The PPARg System in Major Depression: Pathophysiologic and Therapeutic Implications , 2021, International journal of molecular sciences.

[3]  Zhi Sun,et al.  Alpiniae oxyphyllae Fructus and Alzheimer's disease: An update and current perspective on this traditional Chinese medicine. , 2020, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[4]  M. Islam,et al.  Modulatory effect of ursolic acid on neurodegenerative activities in oxidative brain injury: An ex vivo study. , 2020, Journal of food biochemistry.

[5]  S. Chinnathambi,et al.  α-Linolenic acid inhibits tau aggregation and modulates tau conformation. , 2020, International journal of biological macromolecules.

[6]  W. Bik,et al.  The Effects of Alpha-Linolenic Acid on the Secretory Activity of Astrocytes and β Amyloid-Associated Neurodegeneration in Differentiated SH-SY5Y Cells: Alpha-Linolenic Acid Protects the SH-SY5Y cells against β Amyloid Toxicity , 2020, Oxidative medicine and cellular longevity.

[7]  S. Nabavi,et al.  MAP KINASE SIGNALING AS THERAPEUTIC TARGET FOR NEURODEGENERATION. , 2020, Pharmacological research.

[8]  M. Shivakumar,et al.  Antioxidant and Antiproliferative Potential of Bioactive Molecules Ursolic Acid and Thujone Isolated from Memecylon edule and Elaeagnus indica and Their Inhibitory Effect on Topoisomerase II by Molecular Docking Approach , 2020, BioMed research international.

[9]  Xue Xiao,et al.  Network Pharmacology in Research of Chinese Medicine Formula: Methodology, Application and Prospective , 2020, Chinese journal of integrative medicine.

[10]  Blaine H M Mooers,et al.  Shortcuts for faster image creation in PyMOL , 2019, Protein science : a publication of the Protein Society.

[11]  R. Brinton,et al.  Allopregnanolone Reverses Bioenergetic Deficits in Female Triple Transgenic Alzheimer’s Mouse Model , 2019, Neurotherapeutics.

[12]  A. F. Furian,et al.  Chrysin protects against behavioral, cognitive and neurochemical alterations in a 6-hydroxydopamine model of Parkinson's disease , 2019, Neuroscience Letters.

[13]  S. Shui,et al.  Chrysin ameliorates cerebral ischemia/reperfusion (I/R) injury in rats by regulating the PI3K/Akt/mTOR pathway , 2019, Neurochemistry International.

[14]  Olivier Michielin,et al.  SwissTargetPrediction: updated data and new features for efficient prediction of protein targets of small molecules , 2019, Nucleic Acids Res..

[15]  J. Brigman,et al.  Genetic inactivation of hypoxia inducible factor 1-alpha (HIF-1α) in adult hippocampal progenitors impairs neurogenesis and pattern discrimination learning , 2019, Neurobiology of Learning and Memory.

[16]  Wei Chen,et al.  TGF-β1 Restores Hippocampal Synaptic Plasticity and Memory in Alzheimer Model via the PI3K/Akt/Wnt/β-Catenin Signaling Pathway , 2018, Journal of Molecular Neuroscience.

[17]  Wei Zhang,et al.  ETCM: an encyclopaedia of traditional Chinese medicine , 2018, Nucleic Acids Res..

[18]  David S. Goodsell,et al.  RCSB Protein Data Bank: biological macromolecular structures enabling research and education in fundamental biology, biomedicine, biotechnology and energy , 2018, Nucleic Acids Res..

[19]  P. Hof,et al.  The interactions of p53 with tau and Aß as potential therapeutic targets for Alzheimer’s disease , 2018, Progress in Neurobiology.

[20]  J. Haines,et al.  Alzheimer Disease: Perspectives from Epidemiology and Genetics , 2018, The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics.

[21]  Kaishun Bi,et al.  Protective effects of Alpinae Oxyphyllae Fructus extracts on lipopolysaccharide-induced animal model of Alzheimer's disease. , 2018, Journal of ethnopharmacology.

[22]  D. Bennett,et al.  Reactive Oxygen Species-Mediated Loss of Synaptic Akt1 Signaling Leads to Deficient Activity-Dependent Protein Translation Early in Alzheimer's Disease , 2017, Antioxidants & redox signaling.

[23]  Ming Chen,et al.  Inhibitory effect of verbascoside on xanthine oxidase activity. , 2016, International journal of biological macromolecules.

[24]  Núria Queralt-Rosinach,et al.  DisGeNET: a comprehensive platform integrating information on human disease-associated genes and variants , 2016, Nucleic Acids Res..

[25]  Jung-Hye Choi,et al.  Isocyperol, isolated from the rhizomes of Cyperus rotundus, inhibits LPS-induced inflammatory responses via suppression of the NF-κB and STAT3 pathways and ROS stress in LPS-stimulated RAW 264.7 cells. , 2016, International immunopharmacology.

[26]  Alzheimer’s Association,et al.  2016 Alzheimer's disease facts and figures , 2016, Alzheimer's & Dementia.

[27]  M. David,et al.  Neuroprotective Effect of Nanodiamond in Alzheimer’s Disease Rat Model: a Pivotal Role for Modulating NF-κB and STAT3 Signaling , 2016, Molecular Neurobiology.

[28]  Damian Szklarczyk,et al.  STITCH 5: augmenting protein–chemical interaction networks with tissue and affinity data , 2015, Nucleic Acids Res..

[29]  John J. Irwin,et al.  ZINC 15 – Ligand Discovery for Everyone , 2015, J. Chem. Inf. Model..

[30]  Gary D Bader,et al.  Biological Network Exploration with Cytoscape 3 , 2014, Current protocols in bioinformatics.

[31]  Wei Zhou,et al.  TCMSP: a database of systems pharmacology for drug discovery from herbal medicines , 2014, Journal of Cheminformatics.

[32]  Shao Li,et al.  Traditional Chinese medicine network pharmacology: theory, methodology and application. , 2013, Chinese journal of natural medicines.

[33]  W. Klein,et al.  The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer’s disease , 2011, Neurobiology of Learning and Memory.

[34]  E. Boerwinkle,et al.  Mining gold dust under the genome wide significance level: a two‐stage approach to analysis of GWAS , 2011, Genetic epidemiology.

[35]  Tsviya Olender,et al.  GeneCards Version 3: the human gene integrator , 2010, Database J. Biol. Databases Curation.

[36]  A. Olson,et al.  AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading , 2009, J. Comput. Chem..

[37]  Christian von Mering,et al.  STITCH: interaction networks of chemicals and proteins , 2007, Nucleic Acids Res..

[38]  I Ferrer,et al.  N-myc and c-myc expression in Alzheimer disease, Huntington disease and Parkinson disease. , 2000, Brain research. Molecular brain research.

[39]  David Satcher Alzheimer’s Association , 2020, The Grants Register 2022.

[40]  Haruki Nakamura,et al.  Protein Data Bank (PDB): The Single Global Macromolecular Structure Archive. , 2017, Methods in molecular biology.

[41]  D. Selkoe Alzheimer's disease. , 2011, Cold Spring Harbor perspectives in biology.

[42]  Brad T. Sherman,et al.  Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources , 2008, Nature Protocols.

[43]  D. Blacker,et al.  Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database , 2007, Nature Genetics.