Diabetes mellitus after stem cell transplantation in a patient with acute lymphoblastic leukemia: Possible association with tacrolimus

A 14-year-old boy was diagnosed with acute lymphoblastic leukemia. Blasts were morphologically L1 and divided into early B-cell lineage using heteroantisera and monoclonal antibodies. No chromosomal abnormality was detected. After receiving an induction regimen consisting of prednisolone (PSL), vincristine (VCR), daunorubicin (DNR), cyclophosphamide (CY), and L-asparaginase (L-ASP), he achieved complete remission (fi rst CR). He was given consolidation and maintenance therapies consisting (total dose) of 15 g/m 2

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