The new stereological methods for interpreting functional morphology from slices of cells and organs

This review summarizes the rationale of stereology and the most recent developments for estimating the volumes, surface areas, lengths and numbers of structures from the subcellular to the whole organ level

[1]  T M Mayhew,et al.  Magnetic resonance imaging (MRI) and model-free estimates of brain volume determined using the Cavalieri principle. , 1991, Journal of anatomy.

[2]  T. Mayhew,et al.  Oxygen diffusive conductances of human placentae from term pregnancies at low and high altitudes. , 1990, Placenta.

[3]  T. Mayhew,et al.  Comparative morphometry of the mammalian brain: estimates of cerebral volumes and cortical surface areas obtained from macroscopic slices. , 1990, Journal of anatomy.

[4]  Luis M. Cruz-Orive,et al.  On the empirical variance of a fractionator estimate , 1990 .

[5]  Marianne Geiser,et al.  Assessment of particle retention and clearance in the intrapulmonary conducting airways of hamster lungs with the fractionator 1 , 1990, Journal of microscopy.

[6]  T. Mattfeldt,et al.  Estimation of surface area and length with the orientator , 1990, Journal of microscopy.

[7]  Arun M. Gokhale,et al.  Unbiased estimation of curve length in 3‐D using vertical slices , 1990 .

[8]  L. Siklós,et al.  An unbiased estimation of the total number of synapses in the superior cervical ganglion of adult rats established by the disector method. Lack of change after long-lasting sodium bromide administration , 1990, Journal of neurocytology.

[9]  H. Gundersen,et al.  Efficient estimation of cell volume and number using the nucleator and the disector , 1990, Journal of microscopy.

[10]  T. Mayhew,et al.  Fractionator studies on Purkinje cells in the human cerebellum: numbers in right and left halves of male and female brains. , 1990, Journal of anatomy.

[11]  L. Cruz-Orive,et al.  Estimating the total number of lymphatic valves in infant lungs with the fractionator , 1990, Journal of microscopy.

[12]  E R Weibel,et al.  Recent stereological methods for cell biology: a brief survey. , 1990, The American journal of physiology.

[13]  C V Howard,et al.  The total number of neurons in the human neocortex unbiasedly estimated using optical disectors , 1990, Journal of microscopy.

[14]  L. Cruz-Orive,et al.  Increase in hepatocyte and nuclear volume and decrease in the population of binucleated cells in preneoplastic foci of rat liver: A stereological study using the nucleator method , 1990, Hepatology.

[15]  M. J. Moore,et al.  Extensor tendon repair: an animal model which allows immediate post-operative mobilisation. , 1990, Journal of hand surgery.

[16]  T M Mayhew,et al.  On the number of purkinje cells in the human cerebellum: Unbiased estimates obtained by using the “fractionator” , 1989, The Journal of comparative neurology.

[17]  E. Berger,et al.  Mitotic Golgi fragments in HeLa cells and their role in the reassembly pathway , 1989, The Journal of cell biology.

[18]  B. Pakkenberg,et al.  Optimizing sampling designs for volume measurements of components of human brain using a stereological method , 1989, Journal of microscopy.

[19]  G. Burton,et al.  Stereological re-examination of the effects of varying oxygen tensions on human placental villi maintained in organ culture for up to 12 h. , 1989, Placenta.

[20]  G. Warren,et al.  Formation of coated vesicles from coated pits in broken A431 cells , 1989, The Journal of cell biology.

[21]  T. Mayhew.  Stereological studies on rat spinal neurons during postnatal development: estimates of mean perikaryal and nuclear volumes free from assumptions about shape. , 1989, Journal of anatomy.

[22]  S. Fuller,et al.  The dynamic nature of the Golgi complex , 1989, The Journal of cell biology.

[23]  H J Gundersen,et al.  The nucleator , 1988, Journal of microscopy.

[24]  L M Cruz-Orive,et al.  Application of the Cavalieri principle and vertical sections method to lung: estimation of volume and pleural surface area , 1988, Journal of microscopy.

[25]  H J Gundersen,et al.  Total number of neurons and glial cells in human brain nuclei estimated by the disector and the fractionator , 1988, Journal of microscopy.

[26]  H. J. G. GUNDERSEN,et al.  Some new, simple and efficient stereological methods and their use in pathological research and diagnosis , 1988, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

[27]  H J Gundersen,et al.  The efficiency of systematic sampling in stereology and its prediction * , 1987, Journal of microscopy.

[28]  M. J. Moore,et al.  A quantitative ultrastructural study of rat tendon from birth to maturity. , 1987, Journal of anatomy.

[29]  T. Mayhew,et al.  Effects of continuous subcutaneous insulin infusion on renal morphology in experimental diabetes. II. Glomerular basement membrane thickness , 1987, The Journal of pathology.

[30]  L M Cruz-Orive,et al.  Particle number can be estimated using a disector of unknown thickness: the selector. , 1987, Journal of microscopy.

[31]  H. J. G. Gundersen,et al.  The impact of recent stereological advances on quantitative studies of the nervous system , 1986, Journal of Neuroscience Methods.

[32]  E. B. V. Jensen,et al.  Generalized associated point methods for sampling planar objects , 1986 .

[33]  E B Hunziker,et al.  Stereology for anisotropic cells: Application to growth cartilage * , 1986, Journal of microscopy.

[34]  L M Cruz-Orive,et al.  Estimation of surface area from vertical sections , 1986, Journal of microscopy.

[35]  M. Hlastala.  The pathway for Oxygen , 1985 .

[36]  T. Mattfeldt,et al.  Orthogonal triplet probes: an efficient method for unbiased estimation of length and surface of objects with unknown orientation in space , 1985, Journal of microscopy.

[37]  A. Boyde,et al.  Unbiased estimation of particle density in the tandem scanning reflected light microscope , 1985, Journal of microscopy.

[38]  H. Gundersen,et al.  Stereological estimation of the volume‐weighted mean volume of arbitrary particles observed on random sections * , 1985, Journal of microscopy.

[39]  J. T. W. A. Cornelisse,et al.  Profile boundary length can be overestimated by as much as 41% when using a digitizer tablet , 1984 .

[40]  T. Mayhew,et al.  Structure-function correlation in the human placenta: the morphometric diffusing capacity for oxygen at full term. , 1984, Journal of anatomy.

[41]  T M Mayhew,et al.  Sampling schemes for estimating nerve fibre size. II. Methods for unifascicular nerve trunks. , 1984, Journal of anatomy.

[42]  T M Mayhew,et al.  Sampling schemes for estimating nerve fibre size. I. Methods for nerve trunks of mixed fascicularity. , 1984, Journal of anatomy.

[43]  G Hung,et al.  Stereological methods. Vol. 1: Practical methods for biological morphometry By . Academic Press, New York/London, 1979. xvi + 415 pp., $57.50 , 1984 .

[44]  D. C. Sterio.  The unbiased estimation of number and sizes of arbitrary particles using the disector , 1984, Journal of microscopy.

[45]  T. Mayhew,et al.  Inter‐animal variation and its influence on the overall precision of morphometric estimates based on nested sampling designs , 1983, Journal of microscopy.

[46]  P Berggren,et al.  Automated techniques for the study of lung alveolar stereological parameters with the IBAS image analyser on optical microscopy sections , 1983, Journal of microscopy.

[47]  R. Osterby,et al.  Development of glomerular lesions in experimental long-term diabetes in the rat. , 1982, Kidney international.

[48]  D. Wynford‐Thomas,et al.  Physical randomization of tissue architecture: an alternative to systematic sampling , 1982, Journal of microscopy.

[49]  L M Cruz-Orive,et al.  Sampling designs for stereology * , 1981, Journal of microscopy.

[50]  M. Williams,et al.  Membrane dynamics in the parotid acinar cell during regranulation: A stereological study following isoprenaline‐induced secretion , 1981, The Anatomical record.

[51]  R. Østerby,et al.  Optimizing sampling efficiency of stereological studies in biology: or ‘Do more less well!‘ , 1981, Journal of microscopy.

[52]  L M Cruz-Orive,et al.  Measuring error and sampling variation in stereology: comparison of the efficiency of various methods for planar image analysis , 1981, Journal of microscopy.

[53]  H Jørgen,et al.  Estimation of tubule or cylinder LV, SV and VV on thick sections , 1979, Journal of microscopy.

[54]  S Bradbury,et al.  Microscopical Image Analysis: Problems And Approaches * , 1979, Journal of microscopy.

[55]  E. B. Jensen,et al.  Determination of membrane thickness distribution from orthogonal intercepts , 1979, Journal of microscopy.

[56]  W. Thurlbeck,et al.  The use of simple image analysers in lung morphometry , 1978, Journal of microscopy.

[57]  R. Østerby,et al.  Distribution of Membrane Thickness Determined By Lineal Analysis , 1978, Journal of microscopy.

[58]  H. Gundersen,et al.  Notes on the estimation of the numerical density of arbitrary profiles: the edge effect , 1977 .

[59]  J Shay,et al.  Economy of effort in electron microscope morphometry. , 1975, The American journal of pathology.

[60]  W. Scherle,et al.  A simple method for volumetry of organs in quantitative stereology. , 1970, Mikroskopie.

[61]  Bruce W. Knight,et al.  A MORPHOMETRIC STUDY ON THE THICKNESS OF THE PULMONARY AIR-BLOOD BARRIER , 1964, The Journal of cell biology.

[62]  Terry M. Mayhew,et al.  Efficient and Unbiased Sampling of Nerve Fibers for Estimating Fiber Number and Size , 1990 .

[63]  T M Mayhew,et al.  The cerebrum and cerebellum of the fixed human brain: efficient and unbiased estimates of volumes and cortical surface areas. , 1989, Journal of anatomy.

[64]  A. Reith,et al.  Stereology and morphometry in electron microscopy : problems and solutions , 1988 .

[65]  H. Gundersen,et al.  Stereological estimates of nuclear volume correlated with histopathological grading and prognosis of bladder tumour , 1986, Virchows Archiv. B, Cell pathology including molecular pathology.

[66]  H. Gundersen,et al.  The unbiased estimation of number and sizes of arbitrary particles , 1985 .

[67]  Ewald R. Weibel,et al.  The pathway for oxygen : structure and function in the mammalian respiratory system , 1984 .

[68]  A. Reith,et al.  Comparison of semiautomatic digitizer-tablet and simple point counting performance in morphometry , 1981, Virchows Archiv. B, Cell pathology including molecular pathology.

[69]  L. M. Cruz Orive,et al.  On the estimation of particle number. , 1980, Journal of microscopy.

[70]  J. A. C. C. Watson-Gandy,et al.  Basic Ideas of Scientific Sampling , 1977 .