Pharmacokinetic Analysis of the Absorption Characteristics of Diclofenac Sodium in Man by use of a Multi‐segment Absorption Model

The pharmacokinetic analysis of an oral sustained‐release preparation of diclofenac sodium has been investigated using multi‐segment absorption models in which it has been assumed that the gastrointestinal tract can be divided into several segments in each of which the drug has its own lag‐time and absorption rate constants.