Polymer nanofiber reinforced double network gel composite: Strong, tough and transparent

Abstract Double network gel is well known for its extraordinarily high toughness and stretchability. However, compared to many soft biological tissues such as articular cartilage and tendon, both strength and stiffness of double network gel are significantly lower, which greatly limits its further applications. In this article, to improve mechanical properties of double network gel, we embed a small weight percentage of aligned electrospun polymer nanofibers into double network gel matrix to make a sandwich-like double network gel composite. Mechanical tests conducted by us show that polymer nanofiber reinforced double network gel composite has much higher strength and stiffness, while maintaining its good transparency.

[1]  C. Ren.  PAN Nanofibers and Nanofiber Reinforced Composites , 2013 .

[2]  Farshid Guilak,et al.  Composite Three‐Dimensional Woven Scaffolds with Interpenetrating Network Hydrogels to Create Functional Synthetic Articular Cartilage , 2013, Advanced functional materials.

[3]  David C. Martin,et al.  Processing and microstructural characterization of porous biocompatible protein polymer thin films , 1999 .

[4]  Tianyang Cao,et al.  Responsive Double Network Hydrogels of Interpenetrating DNA and CB[8] Host–Guest Supramolecular Systems , 2015, Advanced materials.

[5]  Xuanhe Zhao,et al.  Stretchable Hydrogel Electronics and Devices , 2016, Advanced materials.

[6]  Jason T. George,et al.  Thermoresponsive nanocomposite double network hydrogels. , 2012, Soft matter.

[7]  Parviz Soroushian,et al.  Mechanical properties of polypropylene fiber reinforced concrete and the effects of pozzolanic materials , 1996 .

[8]  Eyal Zussman,et al.  A micro-aerodynamic decelerator based on permeable surfaces of nanofiber mats , 2002 .

[9]  David C. Martin,et al.  Impedance spectroscopy of protein polymer modified silicon micromachined probes , 1999 .

[10]  Yoshimi Tanaka,et al.  Effect of void structure on the toughness of double network hydrogels , 2011 .

[11]  A. K. Agarwal,et al.  Adaptive liquid microlenses activated by stimuli-responsive hydrogels , 2006, Nature.

[12]  Darrell H. Reneker,et al.  Mechanical properties of composites using ultrafine electrospun fibers , 1999 .

[13]  Jian Ping Gong,et al.  Microgel-Reinforced Hydrogel Films with High Mechanical Strength and Their Visible Mesoscale Fracture Structure , 2011 .

[14]  Julianne L. Holloway,et al.  Double network hydrogels prepared from pH-responsive doubly crosslinked microgels , 2013 .

[15]  M. Nogi,et al.  Optically transparent composites reinforced with plant fiber-based nanofibers , 2005 .

[16]  Jason T. George,et al.  Ultra-strong thermoresponsive double network hydrogels. , 2013, Soft matter.

[17]  Elliot L. Chaikof,et al.  Generation of Synthetic Elastin-Mimetic Small Diameter Fibers and Fiber Networks , 2000 .

[18]  Yoshihito Osada,et al.  Biodegradation of high-toughness double network hydrogels as potential materials for artificial cartilage. , 2007, Journal of biomedical materials research. Part A.

[19]  R. Ruoff,et al.  Strength and breaking mechanism of multiwalled carbon nanotubes under tensile load , 2000, Science.

[20]  Yoshihito Osada,et al.  High Mechanical Strength Double‐Network Hydrogel with Bacterial Cellulose , 2004 .

[21]  Jian Ping Gong,et al.  Why are double network hydrogels so tough , 2010 .

[22]  X. Yang,et al.  A novel cellulose hydrogel prepared from its ionic liquid solution , 2009 .

[23]  Animesh Agrawal,et al.  Strong fiber-reinforced hydrogel. , 2013, Acta biomaterialia.

[24]  T. Kurokawa,et al.  Double‐Network Hydrogels with Extremely High Mechanical Strength , 2003 .

[25]  John Layman,et al.  Release of tetracycline hydrochloride from electrospun poly(ethylene-co-vinylacetate), poly(lactic acid), and a blend. , 2002, Journal of controlled release : official journal of the Controlled Release Society.

[26]  Charles M. Lieber,et al.  Nanobeam Mechanics: Elasticity, Strength, and Toughness of Nanorods and Nanotubes , 1997 .

[27]  T. Kurokawa,et al.  Synthesis of hydrogels with extremely low surface friction. , 2001, Journal of the American Chemical Society.

[28]  Z. Suo,et al.  Electroluminescence of Giant Stretchability , 2016, Advanced materials.

[29]  Sanlin S. Robinson,et al.  Highly stretchable electroluminescent skin for optical signaling and tactile sensing , 2016, Science.

[30]  M. Naraghi,et al.  Molecular orientation and mechanical property size effects in electrospun polyacrylonitrile nanofibers , 2011 .

[31]  Darrell H. Reneker,et al.  Electrospinning process and applications of electrospun fibers , 1993, Conference Record of the 1993 IEEE Industry Applications Conference Twenty-Eighth IAS Annual Meeting.

[32]  Y. Osada,et al.  Biomechanical properties of high-toughness double network hydrogels. , 2005, Biomaterials.

[33]  G E Kempson,et al.  Relationship between the tensile properties of articular cartilage from the human knee and age. , 1982, Annals of the rheumatic diseases.

[34]  David L Kaplan,et al.  Electrospinning Bombyx mori silk with poly(ethylene oxide). , 2002, Biomacromolecules.

[35]  Z. Suo,et al.  Fiber-reinforced tough hydrogels , 2014 .

[36]  Z. Suo,et al.  Highly stretchable and tough hydrogels , 2012, Nature.

[37]  Choon Chiang Foo,et al.  Stretchable, Transparent, Ionic Conductors , 2013, Science.

[38]  T. Kurokawa,et al.  A novel double-network hydrogel induces spontaneous articular cartilage regeneration in vivo in a large osteochondral defect. , 2009, Macromolecular bioscience.