Preservation of antigen-specific responses in cryopreserved CD4+ and CD8+ T cells expanded with IL-2 and IL-7

[1]  J. Cheville,et al.  Leucine Zipper 4 Autoantibody: A Novel Germ Cell Tumor and Paraneoplastic Biomarker , 2021, Annals of neurology.

[2]  A. Fiore-Gartland,et al.  Comprehensive epitope mapping using polyclonally expanded human CD8 T cells and a two-step ELISpot assay for testing large peptide libraries. , 2021, Journal of immunological methods.

[3]  M. Meyerson,et al.  Antigen identification for HLA class I– and HLA class II–restricted T cell receptors using cytokine-capturing antigen-presenting cells , 2021, Science Immunology.

[4]  J. P. Martins,et al.  Rapid detection of SARS‐CoV‐2‐specific memory T‐cell immunity in recovered COVID‐19 cases , 2020, Clinical & translational immunology.

[5]  M. Harris,et al.  Optimization of a Method to Detect Autoantigen-Specific T-Cell Responses in Type 1 Diabetes , 2020, Frontiers in Immunology.

[6]  R. Gill,et al.  Diverse Routes of Allograft Tolerance Disruption by Memory T Cells , 2020, Frontiers in Immunology.

[7]  R. Baiocchi,et al.  Immunology of EBV-Related Lymphoproliferative Disease in HIV-Positive Individuals , 2020, Frontiers in Oncology.

[8]  A. Kirk,et al.  Modulating the wayward T cell: New horizons with immune checkpoint inhibitor treatments in autoimmunity, transplant, and cancer. , 2020, Journal of autoimmunity.

[9]  O. Laeyendecker,et al.  Healthy donor T-cell responses to common cold coronaviruses and SARS-CoV-2. , 2020, Journal of Clinical Investigation.

[10]  Y. Oo,et al.  The Next Frontier of Regulatory T Cells: Promising Immunotherapy for Autoimmune Diseases and Organ Transplantations , 2020, Frontiers in Immunology.

[11]  Mark S. Anderson,et al.  Tolerance in the Age of Immunotherapy. , 2020, The New England journal of medicine.

[12]  P. Doherty,et al.  Suboptimal SARS-CoV-2−specific CD8+ T cell response associated with the prominent HLA-A*02:01 phenotype , 2020, Proceedings of the National Academy of Sciences.

[13]  S. Kyuwa,et al.  Role of cytotoxic T lymphocytes and interferon-γ in coronavirus infection: Lessons from murine coronavirus infections in mice , 2020, The Journal of veterinary medical science.

[14]  Chadwick M. Hales,et al.  Expanded Clinical Phenotype, Oncological Associations, and Immunopathologic Insights of Paraneoplastic Kelch-like Protein-11 Encephalitis. , 2020, JAMA neurology.

[15]  K. Blackburn,et al.  Post-infectious neurological disorders , 2020, Therapeutic advances in neurological disorders.

[16]  R. Dale,et al.  Single-cell approaches to investigate B cells and antibodies in autoimmune neurological disorders , 2020, Cellular & Molecular Immunology.

[17]  D. Wraith,et al.  Antigen-Specific Immunotherapy for Treatment of Autoimmune Liver Diseases , 2020, Frontiers in Immunology.

[18]  C. Kiparissides,et al.  Recent Advances in Antigen-Specific Immunotherapies for the Treatment of Multiple Sclerosis , 2020, Brain sciences.

[19]  J. Tavernier,et al.  Tolerizing Strategies for the Treatment of Autoimmune Diseases: From ex vivo to in vivo Strategies , 2020, Frontiers in Immunology.

[20]  E. Campo,et al.  Sampling time-dependent artifacts in single-cell genomics studies , 2020, Genome Biology.

[21]  E. James,et al.  Escherichia coli–Specific CD4+ T Cells Have Public T-Cell Receptors and Low Interleukin 10 Production in Crohn’s Disease , 2020, Cellular and molecular gastroenterology and hepatology.

[22]  A. Boonstra,et al.  Checkpoint Inhibitors and Therapeutic Vaccines for the Treatment of Chronic HBV Infection , 2020, Frontiers in Immunology.

[23]  Y. Oo,et al.  Regulatory T cells in solid organ transplantation , 2020, Clinical & translational immunology.

[24]  P. Calabresi,et al.  Anti-CD20 therapy depletes activated myelin-specific CD8+ T cells in multiple sclerosis , 2019, Proceedings of the National Academy of Sciences.

[25]  A. La Cava,et al.  Rebalancing Immune Homeostasis to Treat Autoimmune Diseases. , 2019, Trends in immunology.

[26]  R. Thimme,et al.  Heterogeneity of HBV-Specific CD8+ T-Cell Failure: Implications for Immunotherapy , 2019, Front. Immunol..

[27]  Mark M. Davis,et al.  Select sequencing of clonally expanded CD8+ T cells reveals limits to clonal expansion , 2019, Proceedings of the National Academy of Sciences.

[28]  N. Goonetilleke,et al.  Harnessing CD8+ T Cells Under HIV Antiretroviral Therapy , 2019, Front. Immunol..

[29]  P. Kaleebu,et al.  Interferon gamma (IFN-γ) negative CD4+ and CD8+ T-cells can produce immune mediators in response to viral antigens , 2019, Vaccine.

[30]  P. Goulder,et al.  HIV control: Is getting there the same as staying there? , 2018, PLoS pathogens.

[31]  S. Varga,et al.  Cytokines and CD8 T cell immunity during respiratory syncytial virus infection , 2018, Cytokine.

[32]  L. Thurgood,et al.  Aberrant determination of phenotypic markers in chronic lymphocytic leukemia (CLL) lymphocytes after cryopreservation. , 2018, Experimental hematology.

[33]  Ilse S. Peterson,et al.  T cell deficiencies as a common risk factor for drug associated progressive multifocal leukoencephalopathy. , 2018, Immunobiology.

[34]  R. Carrio,et al.  A novel dendritic cell-based direct ex vivo assay for detection and enumeration of circulating antigen-specific human T cells , 2018, Cytotechnology.

[35]  Xin Lu,et al.  Identification of an HLA-A2-restricted CD147 epitope that can induce specific CTL cytotoxicity against drug resistant MCF-7/Adr cells. , 2018, Oncology letters.

[36]  A. Nizam,et al.  A High Throughput Whole Blood Assay for Analysis of Multiple Antigen-Specific T Cell Responses in Human Mycobacterium tuberculosis Infection , 2018, The Journal of Immunology.

[37]  S. H. van der Burg,et al.  Features of Effective T Cell-Inducing Vaccines against Chronic Viral Infections , 2018, Front. Immunol..

[38]  M. Pirmohamed,et al.  Application of in Vitro T Cell Assay Using Human Leukocyte Antigen-Typed Healthy Donors for the Assessment of Drug Immunogenicity. , 2018, Chemical research in toxicology.

[39]  L. Watkin,et al.  Severity of Acute Infectious Mononucleosis Correlates with Cross-Reactive Influenza CD8 T-Cell Receptor Repertoires , 2017, mBio.

[40]  A. Shilatifard,et al.  Precancer Atlas to Drive Precision Prevention Trials. , 2017, Cancer research.

[41]  Susan A. Doyle,et al.  Successive annual influenza vaccination induces a recurrent oligoclonotypic memory response in circulating T follicular helper cells , 2017, Science Immunology.

[42]  J. Mesirov,et al.  Leveraging premalignant biology for immune-based cancer prevention , 2016, Proceedings of the National Academy of Sciences.

[43]  E. James,et al.  Efficient ex vivo analysis of CD4+ T-cell responses using combinatorial HLA class II tetramer staining , 2016, Nature Communications.

[44]  Fiorella Kotsias,et al.  Dendritic cell maturation and cross‐presentation: timing matters! , 2016, Immunological reviews.

[45]  J. Schlom,et al.  A fully human IgG1 anti-PD-L1 MAb in an in vitro assay enhances antigen-specific T-cell responses , 2016, Clinical & translational immunology.

[46]  L. Saveanu,et al.  Cross-Presentation of Cell-Associated Antigens by MHC Class I in Dendritic Cell Subsets , 2015, Front. Immunol..

[47]  M. Disis,et al.  The Antigenic Repertoire of Premalignant and High-Risk Lesions , 2015, Cancer Prevention Research.

[48]  R. Valgardsdottir,et al.  A Novel Method Using Blinatumomab for Efficient, Clinical-Grade Expansion of Polyclonal T Cells for Adoptive Immunotherapy , 2014, The Journal of Immunology.

[49]  C. Kesmir,et al.  In vitro expansion of antigen-specific CD8(+) T cells distorts the T-cell repertoire. , 2014, Journal of immunological methods.

[50]  L. Sechi,et al.  Antigenic epitopes of MAP2694 homologous to T-cell receptor gamma-chain are highly recognized in multiple sclerosis Sardinian patients. , 2014, Molecular immunology.

[51]  K. Zänker,et al.  Multiplex and functional detection of antigen-specific human T cells by ITRA--indirect T cell recognition assay. , 2014, Journal of immunological methods.

[52]  C. Qu,et al.  Monocyte-derived dendritic cells: targets as potent antigen-presenting cells for the design of vaccines against infectious diseases. , 2014, International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.

[53]  H. Lassmann,et al.  In situ evidence of JC virus control by CD8+ T cells in PML-IRIS during HIV infection , 2013, Neurology.

[54]  S. Rockman,et al.  Ex Vivo Restimulation of Human PBMC Expands a CD3+CD4−CD8− γδ + T Cell Population That Can Confound the Evaluation of CD4 and CD8 T Cell Responses to Vaccination , 2013, Clinical & developmental immunology.

[55]  William W Kwok,et al.  CD4+ T cells recognize unique and conserved 2009 H1N1 influenza hemagglutinin epitopes after natural infection and vaccination. , 2013, International immunology.

[56]  A. Rickinson,et al.  MHC II tetramers visualize human CD4+ T cell responses to Epstein–Barr virus infection and demonstrate atypical kinetics of the nuclear antigen EBNA1 response , 2013, The Journal of experimental medicine.

[57]  E. Jaffee,et al.  Immunotherapy in preneoplastic disease: targeting early procarcinogenic inflammatory changes that lead to immune suppression and tumor tolerance , 2013, Annals of the New York Academy of Sciences.

[58]  Ton N Schumacher,et al.  Parallel detection of antigen-specific T cell responses by combinatorial encoding of MHC multimers , 2012, Nature Protocols.

[59]  M. Montes,et al.  Cryopreservation modulates the detection of regulatory T cell markers , 2012, Cytometry. Part B, Clinical cytometry.

[60]  S. Pittock,et al.  Paraneoplastic encephalomyelopathies: pathology and mechanisms , 2011, Acta Neuropathologica.

[61]  S. Self,et al.  Equivalence of ELISpot Assays Demonstrated between Major HIV Network Laboratories , 2010, PloS one.

[62]  F. Pereyra,et al.  Perforin Expression Directly Ex Vivo by HIV-Specific CD8+ T-Cells Is a Correlate of HIV Elite Control , 2010, PLoS pathogens.

[63]  W. Hanekom,et al.  Comparison of polyclonal expansion methods to improve the recovery of cervical cytobrush-derived T cells from the female genital tract of HIV-infected women , 2010, Journal of immunological methods.

[64]  K. Wood,et al.  Role of T cells in graft rejection and transplantation tolerance , 2010, Expert review of clinical immunology.

[65]  Evan W. Newell,et al.  Simultaneous detection of many T-cell specificities using combinatorial tetramer staining , 2009, Nature Methods.

[66]  D. Vignali,et al.  Outgrowth of CD4low/negCD25+ T Cells with Suppressor Function in CD4+CD25+ T Cell Cultures upon Polyclonal Stimulation Ex Vivo1 , 2008, The Journal of Immunology.

[67]  Aaron J. Johnson,et al.  A translatable molecular approach to determining CD8 T-cell epitopes in TMEV infection. , 2008, Human immunology.

[68]  H. Volk,et al.  Impact of cell culture media on the expansion efficiency and T-cell receptor Vbeta (TRBV) repertoire of in vitro expanded T cells using feeder cells. , 2008, Medical science monitor : international medical journal of experimental and clinical research.

[69]  M. Roederer,et al.  T-cell quality in memory and protection: implications for vaccine design , 2008, Nature Reviews Immunology.

[70]  S. Ostrand-Rosenberg,et al.  Immune surveillance: a balance between protumor and antitumor immunity. , 2008, Current opinion in genetics & development.

[71]  B. Kaić,et al.  Enumeration of Haemagglutinin‐specific CD8+ T Cells after Influenza Vaccination Using MHC Class I Peptide Tetramers , 2007, Scandinavian journal of immunology.

[72]  S. Endres,et al.  Development of a new protocol for 2-day generation of mature dendritic cells from human monocytes , 2003, Biological Procedures Online.

[73]  Douglas Curran-Everett,et al.  Guidelines for reporting statistics in journals published by the American Physiological Society. , 2004, Physiological genomics.

[74]  R. Steinman,et al.  Cross-presentation of glycolipid from tumor cells loaded with α-galactosylceramide leads to potent and long-lived T cell–mediated immunity via dendritic cells , 2007, The Journal of experimental medicine.

[75]  J. García,et al.  Multifunctional Human Immunodeficiency Virus (HIV) Gag-Specific CD8+ T-Cell Responses in Rectal Mucosa and Peripheral Blood Mononuclear Cells during Chronic HIV Type 1 Infection , 2007, Journal of Virology.

[76]  N. Letvin,et al.  JC virus induces a vigorous CD8+ cytotoxic T cell response in multiple sclerosis patients , 2006, Journal of Neuroimmunology.

[77]  Y. Sung,et al.  Correlation of antiviral T-cell responses with suppression of viral rebound in chronic hepatitis B carriers: a proof-of-concept study , 2006, Gene Therapy.

[78]  Mario Roederer,et al.  HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells. , 2006, Blood.

[79]  V. Cerundolo,et al.  Differences in phenotype and function between spontaneously occurring melan‐A‐, tyrosinase‐ and influenza matrix peptide‐specific CTL in HLA‐A*0201 melanoma patients , 2005, International journal of cancer.

[80]  Todd M. Allen,et al.  HIV-1–specific cytotoxicity is preferentially mediated by a subset of CD8+ T cells producing both interferon-γ and tumor necrosis factor–α , 2004 .

[81]  P. Klenerman,et al.  Ex Vivo Phenotype and Frequency of Influenza Virus-Specific CD4 Memory T Cells , 2004, Journal of Virology.

[82]  R. Andreesen,et al.  Large scale in vitro expansion of polyclonal human CD4+CD25high regulatory T cells , 2004, Cancer Cell International.

[83]  V. Rivera,et al.  Increased CD8+ Cytotoxic T Cell Responses to Myelin Basic Protein in Multiple Sclerosis1 , 2004, The Journal of Immunology.

[84]  A. Perl,et al.  Evaluation of autoimmunity to transaldolase in multiple sclerosis. , 2004, Methods in molecular medicine.

[85]  I. Hedfors,et al.  Polyclonal T-cell activation protocol stimulates preferential expansion of EBV-specific T-cell clones in vitro , 2004, Cancer Immunology, Immunotherapy.

[86]  H. Reijonen,et al.  Detection of CD4+ Autoreactive T Cells in T1D Using HLA Class II Tetramers , 2003, Annals of the New York Academy of Sciences.

[87]  W. Kwok,et al.  HLA Class II-Restricted CD4+ T Cell Responses Directed Against Influenza Viral Antigens Postinfluenza Vaccination 1 , 2003, The Journal of Immunology.

[88]  A. Davis,et al.  Large-Scale Expansion of Dendritic Cell-Primed Polyclonal Human Cytotoxic T-Lymphocyte Lines Using Lymphoblastoid Cell Lines for Adoptive Immunotherapy , 2003, Journal of immunotherapy.

[89]  S. Endres,et al.  Mature Dendritic Cells Derived from Human Monocytes Within 48 Hours: A Novel Strategy for Dendritic Cell Differentiation from Blood Precursors1 , 2003, The Journal of Immunology.

[90]  V. Levitsky,et al.  Cytolytic T cell reactivity to Epstein-Barr virus is lost during in vitro T cell expansion. , 2002, Journal of hematotherapy & stem cell research.

[91]  E. Appella,et al.  Frequencies of tetramer+ T cells specific for the wild-type sequence p53(264-272) peptide in the circulation of patients with head and neck cancer. , 2002, Cancer research.

[92]  R Simon,et al.  Combinatorial Peptide Libraries and Biometric Score Matrices Permit the Quantitative Analysis of Specific and Degenerate Interactions Between Clonotypic TCR and MHC Peptide Ligands1 , 2001, The Journal of Immunology.

[93]  R A Houghten,et al.  Combinatorial peptide libraries as an alternative approach to the identification of ligands for tumor-reactive cytolytic T lymphocytes. , 2001, Cancer research.

[94]  D. Nixon,et al.  Functional Heterogeneity of Cytokines and Cytolytic Effector Molecules in Human CD8+ T Lymphocytes1 , 2001, The Journal of Immunology.

[95]  W. Heath,et al.  Cutting Edge: Intravenous Soluble Antigen Is Presented to CD4 T Cells by CD8− Dendritic Cells, but Cross-Presented to CD8 T Cells by CD8+ Dendritic Cells1 , 2001, The Journal of Immunology.

[96]  R. Steinman,et al.  Brief Definitive Report Dendritic Cells Cross-present Latency Gene Products from Epstein-barr Virus–transformed B Cells and Expand Tumor-reactive Cd8 Ϩ Killer T Cells , 2022 .

[97]  M. Bevan,et al.  Cd8+ but Not Cd8− Dendritic Cells Cross-Prime Cytotoxic T Cells in Vivo , 2000, The Journal of experimental medicine.

[98]  Andrew W. Liu,et al.  MHC class II tetramers identify peptide-specific human CD4(+) T cells proliferating in response to influenza A antigen. , 1999, The Journal of clinical investigation.

[99]  D. Speiser,et al.  High Frequencies of Naive Melan-a/Mart-1–Specific Cd8+ T Cells in a Large Proportion of Human Histocompatibility Leukocyte Antigen (Hla)-A2 Individuals , 1999, The Journal of experimental medicine.

[100]  R. Steinman,et al.  Antigen capture, processing, and presentation by dendritic cells: recent cell biological studies. , 1999, Human immunology.

[101]  M. Connors,et al.  Effects of CD28 costimulation on long-term proliferation of CD4+ T cells in the absence of exogenous feeder cells. , 1997, Journal of immunology.

[102]  H. Lyerly,et al.  Generation of dendritic cells in vitro from peripheral blood mononuclear cells with granulocyte-macrophage-colony-stimulating factor, interleukin-4, and tumor necrosis factor-alpha for use in cancer immunotherapy. , 1997, Annals of surgery.

[103]  K. Rock,et al.  Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules. , 1997, Journal of immunology.

[104]  Marianne Ekman,et al.  Differentiation of human dendritic cells from monocytes in vitro , 1997, European journal of immunology.

[105]  K. Rock,et al.  Characterization of antigen-presenting cells that present exogenous antigens in association with class I MHC molecules. , 1993, Journal of immunology.

[106]  P. Santamaria,et al.  Long term expansion of cytomegalovirus-specific T cell lines in the absence of antigen or antigen-presenting cells. Use of monosized polystyrene particles coated with agonistic antibodies. , 1990, Journal of immunological methods.

[107]  A. Fauci,et al.  Recombinant interleukin-2-induced polyclonal proliferation of in vitro unstimulated human peripheral blood lymphocytes. , 1986, Cellular immunology.

[108]  N. Chiorazzi,et al.  Stimulation of a subset of normal resting T lymphocytes by a monoclonal antibody to a crossreactive determinant of the human T cell antigen receptor , 1985, The Journal of experimental medicine.