Distribution of muscarinic receptor subtype M3 in melanomas and their metastases

Background:  Muscarinic acetylcholine receptors (mR) are involved in the regulation of cancer cell motility and cancer progression. mR have been shown in melanoma cell lines and cryostat sections of melanomas. To substantiate the experimental data, here the correlation of mR‐expression with invasive growth was studied on the cellular level by comparison with HMB‐45 immunoreactivity.

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