Medial prefrontal cortex involvement in aesthetic appreciation of paintings: a tDCS study

Among the brain regions involved in the aesthetic evaluation of paintings, the prefrontal cortex seems to play a pivotal role. In particular, consistent neuroimaging evidence indicates that activity in the dorsolateral prefrontal cortex (mainly in the left hemisphere) and in medial and orbital sectors of the prefrontal cortex is linked to viewing aesthetically pleasing images. In this study, we focused on the contribution of the medial prefrontal cortex (mPFC) in mediating aesthetic decisions about paintings. We found that enhancing excitability in this region via anodal tDCS led participants to judge paintings as more beautiful. Although significant, the effects were moderate, possibly due to the neutral affective value of the artworks we used, suggesting that activity in mPFC may be critically dependent on the affective impact of the paintings.

[1]  Paul J. Silvia,et al.  An Introduction to Multilevel Modeling for Research on the Psychology of Art and Creativity , 2007 .

[2]  Juha Silvanto,et al.  The role of the lateral occipital cortex in aesthetic appreciation of representational and abstract paintings: A TMS study , 2015, Brain and Cognition.

[3]  Wei Zhang,et al.  Neural correlates for aesthetic appraisal of pictograph and its referent: An fMRI study , 2016, Behavioural Brain Research.

[4]  Simon B. Eickhoff,et al.  Naturalizing aesthetics: Brain areas for aesthetic appraisal across sensory modalities , 2011, NeuroImage.

[5]  Helmut Leder,et al.  Art in Time and Space: Context Modulates the Relation between Art Experience and Viewing Time , 2014, PloS one.

[6]  Alexander Opitz,et al.  How the brain tissue shapes the electric field induced by transcranial magnetic stimulation , 2011, NeuroImage.

[7]  C. Mirasso,et al.  Sex-related similarities and differences in the neural correlates of beauty , 2009, Proceedings of the National Academy of Sciences.

[8]  Alexander Opitz,et al.  Spatiotemporal structure of intracranial electric fields induced by transcranial electric stimulation in humans and nonhuman primates , 2016, Scientific Reports.

[9]  Svein Magnussen,et al.  Expertise in Pictorial Perception: Eye-Movement Patterns and Visual Memory in Artists and Laymen , 2007, Perception.

[10]  C. Papagno,et al.  Transcranial direct current stimulation over Broca's region improves phonemic and semantic fluency in healthy individuals , 2011, Neuroscience.

[11]  Oshin Vartanian,et al.  Preference for curvilinear contour in interior architectural spaces: Evidence from experts and nonexperts. , 2017, Psychology of Aesthetics, Creativity, and the Arts.

[12]  Edward A. Vessel,et al.  Art reaches within: aesthetic experience, the self and the default mode network , 2013, Front. Neurosci..

[13]  Roberto Cabeza,et al.  Remembering beauty: Roles of orbitofrontal and hippocampal regions in successful memory encoding of attractive faces , 2011, NeuroImage.

[14]  Takanori Kochiyama,et al.  Causal relationship between effective connectivity within the default mode network and mind-wandering regulation and facilitation , 2016, NeuroImage.

[15]  D. Barr,et al.  Random effects structure for confirmatory hypothesis testing: Keep it maximal. , 2013, Journal of memory and language.

[16]  Z. Cattaneo,et al.  TMS over the superior temporal sulcus affects expressivity evaluation of portraits , 2018, Cognitive, Affective, & Behavioral Neuroscience.

[17]  Frans W. Cornelissen,et al.  Neural Correlates of Visual Aesthetics – Beauty as the Coalescence of Stimulus and Internal State , 2012, PloS one.

[18]  T. Jacobsen,et al.  Art schema effects on affective experience: The case of disgusting images. , 2014 .

[19]  Tony W Wilson,et al.  tDCS Modulates Visual Gamma Oscillations and Basal Alpha Activity in Occipital Cortices: Evidence from MEG , 2018, Cerebral cortex.

[20]  Carlotta Lega,et al.  The world can look better: enhancing beauty experience with brain stimulation. , 2014, Social cognitive and affective neuroscience.

[21]  D. A. Kenny,et al.  Experiments with More Than One Random Factor: Designs, Analytic Models, and Statistical Power , 2017, Annual review of psychology.

[22]  Thomas E. Nichols,et al.  Activation of the medial prefrontal cortex and extended amygdala by individual ratings of emotional arousal: a fMRI study , 2003, Biological Psychiatry.

[23]  Tom A. B. Snijders,et al.  Multilevel Analysis , 2011, International Encyclopedia of Statistical Science.

[24]  S. Zeki,et al.  Neural correlates of beauty. , 2004, Journal of neurophysiology.

[25]  Olivier A. Coubard,et al.  Transcranial magnetic stimulation in basic and clinical neuroscience: A comprehensive review of fundamental principles and novel insights , 2017, Neuroscience & Biobehavioral Reviews.

[26]  C. Urgesi,et al.  Different contributions of visual and motor brain areas during liking judgments of same- and different-gender bodies , 2016, Brain Research.

[27]  Rita Z. Goldstein,et al.  Neuroimaging cognitive reappraisal in clinical populations to define neural targets for enhancing emotion regulation. A systematic review , 2017, NeuroImage.

[28]  C. van Leeuwen,et al.  Style and Spectral Power: Processing of Abstract and Representational Art in Artists and Non-Artists , 2010, Perception.

[29]  Hayley Thair,et al.  Transcranial Direct Current Stimulation (tDCS): A Beginner's Guide for Design and Implementation , 2017, Front. Neurosci..

[30]  Paul J. Whalen,et al.  Are Attractive People Rewarding? Sex Differences in the Neural Substrates of Facial Attractiveness , 2008, Journal of Cognitive Neuroscience.

[31]  C. Mirasso,et al.  Dynamics of brain networks in the aesthetic appreciation , 2013, Proceedings of the National Academy of Sciences.

[32]  C. Padoa-Schioppa,et al.  Annals of the New York Academy of Sciences the Orbitofrontal Cortex and the Computation of Subjective Value: Consolidated Concepts and New Perspectives , 2022 .

[33]  Russell A. Epstein,et al.  Common and Unique Representations in pFC for Face and Place Attractiveness , 2015, Journal of Cognitive Neuroscience.

[34]  A. Crawley,et al.  Viewing artworks: Contributions of cognitive control and perceptual facilitation to aesthetic experience , 2009, Brain and Cognition.

[35]  Rüdiger J Seitz,et al.  Functional modularity of the medial prefrontal cortex: involvement in human empathy. , 2006, Neuropsychology.

[36]  Christophe Geuzaine,et al.  Gmsh: A 3‐D finite element mesh generator with built‐in pre‐ and post‐processing facilities , 2009 .

[37]  Dean Sabatinelli,et al.  Noninvasive Stimulation of the Ventromedial Prefrontal Cortex Enhances Pleasant Scene Processing , 2017, Cerebral cortex.

[38]  S. Zeki,et al.  Toward A Brain-Based Theory of Beauty , 2011, PloS one.

[39]  H. Siebner,et al.  Can Transcranial Electrical Stimulation Localize Brain Function? , 2019, Front. Psychol..

[40]  V. Gallese,et al.  Motion, emotion and empathy in esthetic experience , 2007, Trends in Cognitive Sciences.

[41]  Gregg H. Recanzone,et al.  Transcranial electrical stimulation , 2017, Current Biology.

[42]  K. Berridge,et al.  Pleasure Systems in the Brain , 2015, Neuron.

[43]  L. Cohen,et al.  Transcranial DC stimulation (tDCS): A tool for double-blind sham-controlled clinical studies in brain stimulation , 2006, Clinical Neurophysiology.

[44]  Axel Thielscher,et al.  Field modeling for transcranial magnetic stimulation: A useful tool to understand the physiological effects of TMS? , 2015, 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[45]  N. Salkind,et al.  Gender and Age Differences in Preference for Works of Art. , 1997 .

[46]  Roel Bosker,et al.  Multilevel analysis : an introduction to basic and advanced multilevel modeling , 1999 .

[47]  E. Ciaramelli,et al.  Transcranial direct current stimulation of the medial prefrontal cortex dampens mind-wandering in men , 2017, Scientific Reports.

[48]  S. Sato,et al.  Safety and cognitive effect of frontal DC brain polarization in healthy individuals , 2005, Neurology.

[49]  M. Hallett,et al.  A finite element analysis of the effect of electrode area and inter-electrode distance on the spatial distribution of the current density in tDCS , 2011, Journal of neural engineering.

[50]  Vittorio Gallese,et al.  Human, Nature, Dynamism: The Effects of Content and Movement Perception on Brain Activations during the Aesthetic Judgment of Representational Paintings , 2016, Front. Hum. Neurosci..

[51]  M. Nadal,et al.  Art is not special: an assault on the last lines of defense against the naturalization of the human mind , 2018, Reviews in the neurosciences.

[52]  Walter Paulus,et al.  Spatial Working Memory in Humans Depends on Theta and High Gamma Synchronization in the Prefrontal Cortex , 2016, Current Biology.

[53]  P. Lang.  International affective picture system (IAPS) : affective ratings of pictures and instruction manual , 2005 .

[54]  S. Zeki,et al.  The experience of beauty derived from sorrow , 2017, Human brain mapping.

[55]  M. Koslowsky,et al.  tDCS polarity effects in motor and cognitive domains: a meta-analytical review , 2011, Experimental Brain Research.

[56]  T. Egner,et al.  Emotional processing in anterior cingulate and medial prefrontal cortex , 2011, Trends in Cognitive Sciences.

[57]  R Core Team,et al.  R: A language and environment for statistical computing. , 2014 .

[58]  R. Baayen,et al.  Mixed-effects modeling with crossed random effects for subjects and items , 2008 .

[59]  D. A. Kenny,et al.  Treating stimuli as a random factor in social psychology: a new and comprehensive solution to a pervasive but largely ignored problem. , 2012, Journal of personality and social psychology.

[60]  Alberto Pisoni,et al.  The role of the occipital face area in holistic processing involved in face detection and discrimination: A tDCS study. , 2015, Neuropsychology.

[61]  P. Brockhoff,et al.  lmerTest: Tests for random and fixed effects for linear mixed effect models (lmer objects of lme4 package) , 2014 .

[62]  Mascha van 't Wout,et al.  Modulating what is and what could have been: The effect of transcranial direct current stimulation on the evaluation of attained and unattained decision outcomes , 2017, Cognitive, Affective, & Behavioral Neuroscience.

[63]  Z. Cattaneo.  Noninvasive Brain Stimulation: An Overview of Available Approaches for Research in Neuroaesthetics , 2018, Empirical Studies of the Arts.

[64]  D. Yves von Cramon,et al.  Brain correlates of aesthetic judgment of beauty , 2006, NeuroImage.

[65]  Mark S. George,et al.  The Clinical TMS Society Consensus Review and Treatment Recommendations for TMS Therapy for Major Depressive Disorder , 2016, Brain Stimulation.

[66]  Alexander Opitz,et al.  Impact of the gyral geometry on the electric field induced by transcranial magnetic stimulation , 2011, NeuroImage.

[67]  Alberto Fernández,et al.  Activation of the prefrontal cortex in the human visual aesthetic perception. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[68]  Timothy J. Robinson,et al.  Multilevel Analysis: Techniques and Applications , 2002 .

[69]  K. Liebal,et al.  Gaze Duration Biases for Colours in Combination with Dissonant and Consonant Sounds: A Comparative Eye-Tracking Study with Orangutans , 2015, PloS one.

[70]  M. K. Albert.  Surface perception and the generic view principle , 2001, Trends in Cognitive Sciences.

[71]  M. Bikson,et al.  Frontal tDCS modulates orbitofrontal reality filtering , 2014, Neuroscience.

[72]  J. Jovicich,et al.  The role of medial prefrontal cortex in processing emotional self-referential information: a combined TMS/fMRI study , 2018, Brain Imaging and Behavior.

[73]  Oshin Vartanian,et al.  Neuroanatomical correlates of aesthetic preference for paintings , 2004, Neuroreport.

[74]  John B. Nezlek,et al.  Personality and Social Psychology Bulletin Nezlek / Multilevel Random Coefficient Analyses Multilevel Random Coefficient Analyses of Event-and Interval-contingent Data in Social and Personality Psychology Research , 2022 .

[75]  J. Hox.  Multilevel analysis: Techniques and applications, 2nd ed. , 2010 .

[76]  E. Murray,et al.  The role of the anterior cingulate cortex in choices based on reward value and reward contingency. , 2013, Cerebral cortex.

[77]  D. Zaidel,et al.  Where does brain neural activation in aesthetic responses to visual art occur? Meta-analytic evidence from neuroimaging studies , 2016, Neuroscience & Biobehavioral Reviews.

[78]  H. Kawabata,et al.  Transcranial Direct Current Stimulation over the Medial Prefrontal Cortex and Left Primary Motor Cortex (mPFC-lPMC) Affects Subjective Beauty but Not Ugliness , 2015, Front. Hum. Neurosci..

[79]  A. Chatterjee,et al.  Annals of the New York Academy of Sciences Neuroscience of Aesthetics , 2022 .

[80]  J. Ford,et al.  Default mode network activity and connectivity in psychopathology. , 2012, Annual review of clinical psychology.

[81]  Z. Cattaneo,et al.  I find you more attractive … after (prefrontal cortex) stimulation , 2015, Neuropsychologia.

[82]  E. Koster,et al.  The combined cognitive bias hypothesis in depression. , 2012, Clinical psychology review.

[83]  Edward A. Vessel,et al.  The brain on art: intense aesthetic experience activates the default mode network , 2012, Front. Hum. Neurosci..

[84]  Clay B. Holroyd,et al.  Reward-based contextual learning supported by anterior cingulate cortex , 2017, Cognitive, affective & behavioral neuroscience.

[85]  Oshin Vartanian,et al.  Neuroaesthetics , 2016, Perspectives on psychological science : a journal of the Association for Psychological Science.

[86]  T. Vecchi,et al.  The dorsomedial prefrontal cortex mediates the interaction between moral and aesthetic valuation: a TMS study on the beauty-is-good stereotype , 2017, Social cognitive and affective neuroscience.

[87]  D. Polzella.  Differences in reactions to paintings by male and female college students. , 2000, Perceptual and motor skills.

[88]  A. Brunoni,et al.  A Systematic Review and Meta-Analysis of the Effects of Transcranial Direct Current Stimulation (tDCS) Over the Dorsolateral Prefrontal Cortex in Healthy and Neuropsychiatric Samples: Influence of Stimulation Parameters , 2016, Brain Stimulation.

[89]  G. Cupchik,et al.  Individual differences as predictors of preference in visual art , 1985 .

[90]  Yu-chu Yeh,et al.  Associated and dissociated neural substrates of aesthetic judgment and aesthetic emotion during the appreciation of everyday designed products , 2015, Neuropsychologia.

[91]  Steven G. Luke,et al.  Evaluating significance in linear mixed-effects models in R , 2016, Behavior Research Methods.

[92]  Adrian Furnham,et al.  The influence of personality traits, previous experience of art, and demographic variables on artistic preference , 2001 .

[93]  Simone Kühn,et al.  The neural correlates of subjective pleasantness , 2012, NeuroImage.

[94]  Avinash R. Vaidya,et al.  Ventromedial Frontal Lobe Damage Alters how Specific Attributes are Weighed in Subjective Valuation , 2018, Cerebral cortex.

[95]  Robert S. Stawski,et al.  Multilevel Analysis: An Introduction to Basic and Advanced Multilevel Modeling (2nd Edition) , 2013 .

[96]  Emily S. Cross,et al.  Shaping and reshaping the aesthetic brain: Emerging perspectives on the neurobiology of embodied aesthetics , 2016, Neuroscience & Biobehavioral Reviews.

[97]  Lotfi B. Merabet,et al.  The role of prefrontal and parietal cortices in esthetic appreciation of representational and abstract art: A TMS study , 2014, NeuroImage.

[98]  J. Mattingley,et al.  Applications of transcranial direct current stimulation for understanding brain function , 2014, Trends in Neurosciences.

[99]  K. Hennig-Fast,et al.  Is it the picture or is it the frame? An fMRI study on the neurobiology of framing effects , 2015, Front. Hum. Neurosci..

[100]  Z. Cattaneo,et al.  A TMS study on the contribution of visual area V5 to the perception of implied motion in art and its appreciation , 2017, Cognitive neuroscience.

[101]  Paul Hekkert,et al.  Beauty in the eye of expert and nonexpert beholders : A study in the appraisal of art , 1996 .

[102]  A. Thielscher,et al.  Effects of transcranial direct current stimulation for treating depression: A modeling study. , 2018, Journal of affective disorders.

[103]  Martin Skov,et al.  Brain correlates of aesthetic expertise: A parametric fMRI study , 2009, Brain and Cognition.

[104]  L. Cohen,et al.  Transcranial direct current stimulation: State of the art 2008 , 2008, Brain Stimulation.

[105]  S. Zeki,et al.  The brain's specialized systems for aesthetic and perceptual judgment , 2013, The European journal of neuroscience.

[106]  Alexander Opitz,et al.  Brain state and polarity dependent modulation of brain networks by transcranial direct current stimulation , 2017, bioRxiv.

[107]  Enyan Yu,et al.  High-sensitivity neuroimaging biomarkers for the identification of amnestic mild cognitive impairment based on resting-state fMRI and a triple network model , 2017, Brain Imaging and Behavior.

[108]  D. Gooding,et al.  The Predictive Value of the NEO-FFI Items: Parsing the Nature of Social Anhedonia Using the Revised Social Anhedonia Scale and the ACIPS , 2017, Front. Psychol..