Hypomethylation of long interspersed nuclear element-1 in hepatocellular carcinomas

[1]  A. Mutirangura,et al.  LINE‐ 1 hypomethylation level as a potential prognostic factor for epithelial ovarian cancer , 2008, International journal of gynecological cancer : official journal of the International Gynecological Cancer Society.

[2]  S. Ogino,et al.  LINE‐1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer , 2008, International journal of cancer.

[3]  A. Jemal,et al.  Cancer Statistics, 2008 , 2008, CA: a cancer journal for clinicians.

[4]  T. Bagnyukova,et al.  Epigenetic changes in the rat livers induced by pyrazinamide treatment. , 2007, Toxicology and applied pharmacology.

[5]  D. Calvisi,et al.  Altered methionine metabolism and global DNA methylation in liver cancer: Relationship with genomic instability and prognosis , 2007, International journal of cancer.

[6]  J. Califano,et al.  DNA global hypomethylation in squamous cell head and neck cancer associated with smoking, alcohol consumption and stage , 2007, International journal of cancer.

[7]  Y. Jeng,et al.  Differential DNA methylation associated with hepatitis B virus infection in hepatocellular carcinoma , 2007, International journal of cancer.

[8]  S. Thorgeirsson,et al.  Mechanistic and prognostic significance of aberrant methylation in the molecular pathogenesis of human hepatocellular carcinoma. , 2007, The Journal of clinical investigation.

[9]  J. Issa,et al.  Hypomethylation of LINE-1 and Alu in well-differentiated neuroendocrine tumors (pancreatic endocrine tumors and carcinoid tumors) , 2007, Modern Pathology.

[10]  J. Issa,et al.  LINE-1 Hypomethylation in Cancer Is Highly Variable and Inversely Correlated with Microsatellite Instability , 2007, PloS one.

[11]  E. Yu,et al.  Aberrant epigenetic modifications in hepatocarcinogenesis induced by hepatitis B virus X protein. , 2007, Gastroenterology.

[12]  Apiwat Mutirangura,et al.  Serum LINE-1 hypomethylation as a potential prognostic marker for hepatocellular carcinoma. , 2007, Clinica chimica acta; international journal of clinical chemistry.

[13]  N. Cho,et al.  Hypermethylation of CpG island loci and hypomethylation of LINE‐1 and Alu repeats in prostate adenocarcinoma and their relationship to clinicopathological features , 2007, The Journal of pathology.

[14]  M. Fraga,et al.  Chromosomal instability correlates with genome-wide DNA demethylation in human primary colorectal cancers. , 2006, Cancer research.

[15]  W. Schulz,et al.  DNA methylation alterations in urothelial carcinoma , 2006, Cancer biology & therapy.

[16]  Christian B. Woods,et al.  Quantitative analysis of associations between DNA hypermethylation, hypomethylation, and DNMT RNA levels in ovarian tumors , 2006, Oncogene.

[17]  B. Leggett,et al.  Review of genetic and epigenetic alterations in hepatocarcinogenesis , 2006, Journal of gastroenterology and hepatology.

[18]  F. Prósper,et al.  Promoter hypomethylation of the LINE-1 retrotransposable elements activates sense/antisense transcription and marks the progression of chronic myeloid leukemia , 2005, Oncogene.

[19]  Apiwat Mutirangura,et al.  Distinctive pattern of LINE-1 methylation level in normal tissues and the association with carcinogenesis , 2004, Oncogene.

[20]  J. Issa,et al.  A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements. , 2004, Nucleic acids research.

[21]  David I. K. Martin,et al.  Hypomethylation of L1 retrotransposons in colorectal cancer and adjacent normal tissue , 2004, International Journal of Colorectal Disease.

[22]  R. Ward,et al.  The relationship between hypomethylation and CpG island methylation in colorectal neoplasia. , 2003, The American journal of pathology.

[23]  H. Kazazian,et al.  LINE Drive Retrotransposition and Genome Instability , 2002, Cell.

[24]  S. Thorgeirsson,et al.  Molecular pathogenesis of human hepatocellular carcinoma , 2002, Nature Genetics.

[25]  Peter A. Jones,et al.  The fundamental role of epigenetic events in cancer , 2002, Nature Reviews Genetics.

[26]  Nita Ahuja,et al.  DNA methylation and environmental exposures in human hepatocellular carcinoma. , 2002, Journal of the National Cancer Institute.

[27]  E. Ostertag,et al.  Biology of mammalian L1 retrotransposons. , 2001, Annual review of genetics.

[28]  Y. Liaw,et al.  Genome-wide hypomethylation in hepatocellular carcinogenesis. , 2001, Cancer research.

[29]  D. Takai,et al.  Hypomethylation of LINE1 retrotransposon in human hepatocellular carcinomas, but not in surrounding liver cirrhosis. , 2000, Japanese journal of clinical oncology.

[30]  M. Ehrlich,et al.  DNA hypomethylation and unusual chromosome instability in cell lines fromICF syndrome patients , 2000, Cytogenetic and Genome Research.

[31]  Issa Jp.  CpG-island methylation in aging and cancer. , 2000 .

[32]  J. Issa,et al.  CpG-island methylation in aging and cancer. , 2000, Current topics in microbiology and immunology.

[33]  J. Herman,et al.  CpG island methylator phenotype in colorectal cancer. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[34]  W. Schulz,et al.  High frequency of alterations in DNA methylation in adenocarcinoma of the prostate , 1999, The Prostate.

[35]  M. Cravo,et al.  Global DNA hypomethylation in breast carcinoma , 1999, Cancer.

[36]  P. Jones,et al.  Altered DNA methylation and genome instability: a new pathway to cancer? , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[37]  K. Kinzler,et al.  DNA methylation and genetic instability in colorectal cancer cells. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[38]  L. Glória,et al.  Global DNA hypomethylation occurs in the early stages of intestinal type gastric carcinoma. , 1996, Gut.

[39]  A. Feinberg,et al.  Hypomethylation distinguishes genes of some human cancers from their normal counterparts , 1983, Nature.