The prevalence of respiratory diseases associated with herpes infection under conditions of aerotechnogenic exposure to chemicals in children

Introduction. Respiratory diseases consistently occupy a leading position in the structure of pediatric pathology. Materials and methods. We performed clinical examination of 5-17 years four hundred ninety six children living at a large industrial center, on a territory with a relatively favourable sanitary-hygienic situation. The examination involved establishing markers of Herpes simplex, and chemical and analytical blood tests aimed at determining contents of technogenic chemicals in it. Results. In 29.7-66.1% children living in the industrial center elevated blood levels of benzene, p-, m-xylene, manganese and zinc are recorded relative to background levels. Up to 77.6% of children in the observation group had markers of the virus Epstein-Barr, cytomegalovirus, 48.2% - Herpes simplex virus type 1.2. In ¾ of children, respiratory diseases are represented by inflammatory diseases of the nasal mucosa (53.4%) and chronic lymphoproliferative pathology of the nasopharynx (58.2%), associated with increased blood levels of chemicals and the level of markers of Herpes simplex type 1.2, virus Epstein-Barr. The risk of developing chronic lymphoproliferative pathology in children of the observation group is 1.3 times higher. In 39.8% of cases, an intrasystemic comorbidity of respiratory diseases is formed. In 29.1-48.5% of children with respiratory pathology, thyroid diseases, vegetative dystonia, functional heart pathology are registered due to the combined effect of elevated blood levels of aromatic hydrocarbons, formaldehyde, metals and the level of markers of Herpes simplex type 1.2, virus Epstein-Barr. Under conditions of aerogenic pollution with technogenic chemical factors, the risk of developing intra-system and inter-system comorbidity increases up to 1.6 times. Limitations. The study was conducted in 5-17 years children on a representative sample. Conclusion. In conditions of aerotechnogenic exposure to chemicals, the prevalence of respiratory diseases associated with herpes infection in children is higher, which must be taken into account when carrying out preventive measures.