TREAT-NMD workshop: Pattern recognition in genetic muscle diseases using muscle MRI 25–26 February 2011, Rome, Italy

The TREAT-NMD workshop on pattern recognition by magnetic resonance imaging (MRI) of skeletal muscle is one in a series of workshops that have been organised by TREAT-NMD to discuss the application of MRI in neuromuscular diseases. In recent years MRI has become more widely used in patients with neuromuscular diseases because the extent and localisation of muscle pathology can provide useful information for the diagnostic workup of patients. In a number of diseases the pattern of selected muscle involvement detected by MRI can almost be pathognomonic and can therefore guide genetic testing, besides the advantage of targeting the optimal muscle for biopsy. Various groups have now reported their experience with muscle MRI in defined patient cohorts and have started to delineate specific patterns of muscle pathology. Muscle pathology in degenerative diseases can be described on T1 weighted axial images of the pelvic girdle and leg muscles and refers to fatty replacement of skeletal muscle tissue. There is still fairly little experience in describing muscle pathology by whole-body MRI or MRI of the truncal and upper limb muscles, although several centres are now starting to explore these applications more systematically. The degree of muscle pathology can be described semiquantitatively using various scales that have been suggested

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