Triggered Cell Release from Materials Using Bioadhesive Photocleavable Linkers

The ability to trigger or turn “on” or “off” material properties with external stimuli in order to control biological responses is critically important to biotechnological and biomedical applications. One such application is the use of light to trigger cell adhesion to synthetic materials by controlling the presentation of the bioadhesive arginine-glycine-aspartic acid (RGD) oligopeptide. Successful strategies for photoactivation of cell adhesion include direct modifi cation of the chemical structure of the RGD peptide with photoresponsive molecules, [ 1 ]

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