Activation of Akt/protein kinase B after stimulation with angiotensin II in vascular smooth muscle cells.
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U. Kikkawa | H. Konishi | M. Yokoyama | Tomosaburou Takahashi | T. Taniguchi | Y. Ishikawa | Tomosaburo Takahashi
[1] K. Siddle,et al. Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling. , 1998, The Biochemical journal.
[2] J. Downward. Mechanisms and consequences of activation of protein kinase B/Akt. , 1998, Current opinion in cell biology.
[3] M. Yokoyama,et al. Tyrosine phosphorylation and association of p130Cas and c-Crk II by ANG II in vascular smooth muscle cells. , 1998, American journal of physiology. Heart and circulatory physiology.
[4] Brian A. Hemmings,et al. G-Protein-coupled Receptors and Fcγ-receptors Mediate Activation of Akt/Protein Kinase B in Human Phagocytes* , 1997, The Journal of Biological Chemistry.
[5] P. Zahradka,et al. Angiotensin II activates phosphatidylinositol 3-kinase in vascular smooth muscle cells. , 1997, Circulation research.
[6] B. Hemmings. Update: PtdIns(3,4,5)P3 Gets Its Message Across , 1997, Science.
[7] A. Takeshita,et al. Angiotensin II Stimulates Mitogen-activated Protein Kinases and Protein Synthesis by a Ras-independent Pathway in Vascular Smooth Muscle Cells* , 1997, The Journal of Biological Chemistry.
[8] E. Van Obberghen,et al. cAMP stimulates protein kinase B in a Wortmannin‐insensitive manner , 1997, FEBS letters.
[9] Asim Khwaja,et al. Matrix adhesion and Ras transformation both activate a phosphoinositide 3‐OH kinase and protein kinase B/Akt cellular survival pathway , 1997, The EMBO journal.
[10] B. Berk,et al. Angiotensin II signal transduction in vascular smooth muscle: role of tyrosine kinases. , 1997, Circulation research.
[11] N. J. Edgell,et al. Regulation of protein kinase B and glycogen synthase kinase-3 by insulin and beta-adrenergic agonists in rat epididymal fat cells. Activation of protein kinase B by wortmannin-sensitive and -insensitive mechanisms. , 1997, The Journal of biological chemistry.
[12] A. Klippel,et al. Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt , 1997, Molecular and cellular biology.
[13] Lewis C Cantley,et al. PI3K: Downstream AKTion Blocks Apoptosis , 1997, Cell.
[14] G. Evan,et al. Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB , 1997, Nature.
[15] David R. Kaplan,et al. Regulation of Neuronal Survival by the Serine-Threonine Protein Kinase Akt , 1997, Science.
[16] B. Hemmings. Akt Signaling--Linking Membrane Events to Life and Death Decisions , 1997, Science.
[17] David R. Kaplan,et al. Direct Regulation of the Akt Proto-Oncogene Product by Phosphatidylinositol-3,4-bisphosphate , 1997, Science.
[18] P. Warne,et al. R-Ras can activate the phosphoinositide 3-kinase but not the MAP kinase arm of the Ras effector pathways , 1997, Current Biology.
[19] R. Alexander,et al. Angiotensin II signaling in vascular smooth muscle. New concepts. , 1997, Hypertension.
[20] P. Tsichlis,et al. Akt Is a Direct Target of the Phosphatidylinositol 3-Kinase , 1996, The Journal of Biological Chemistry.
[21] M. Horiuchi,et al. Vasoactive substances regulate vascular smooth muscle cell apoptosis. Countervailing influences of nitric oxide and angiotensin II. , 1996, Circulation research.
[22] M. Yokoyama,et al. Angiotensin II type 1 receptor-mediated activation of Ras in cultured rat vascular smooth muscle cells. , 1996, The American journal of physiology.
[23] A. Klippel,et al. Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways , 1996, Molecular and cellular biology.
[24] H. Matsuzaki,et al. Activation of RAC-protein kinase by heat shock and hyperosmolarity stress through a pathway independent of phosphatidylinositol 3-kinase. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[25] S. Eguchi,et al. Identification of an Essential Signaling Cascade for Mitogen-activated Protein Kinase Activation by Angiotensin II in Cultured Rat Vascular Smooth Muscle Cells , 1996, The Journal of Biological Chemistry.
[26] M. Andjelkovic,et al. Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[27] R. Alexander,et al. Angiotensin receptors and their therapeutic implications. , 1996, Annual review of pharmacology and toxicology.
[28] P. Cohen,et al. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B , 1995, Nature.
[29] M. Ishida,et al. Angiotensin II activates pp60c-src in vascular smooth muscle cells. , 1995, Circulation research.
[30] S. Meloche,et al. Involvement of a tyrosine kinase pathway in the growth-promoting effects of angiotensin II on aortic smooth muscle cells. , 1995, Molecular pharmacology.
[31] R. Roth,et al. Insulin stimulates the kinase activity of RAC‐PK, a pleckstrin homology domain containing ser/thr kinase. , 1995, The EMBO journal.
[32] B. Burgering,et al. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction , 1995, Nature.
[33] P. Libby,et al. Evidence for apoptosis in advanced human atheroma. Colocalization with interleukin-1 beta-converting enzyme. , 1995, The American journal of pathology.
[34] M. Leon,et al. Evidence for apoptosis in human atherogenesis and in a rat vascular injury model. , 1995, The American journal of pathology.
[35] M. Hoshijima,et al. Angiotensin II transduces its signal to focal adhesions via angiotensin II type 1 receptors in vascular smooth muscle cells , 1995, FEBS letters.
[36] Andrius Kazlauskas,et al. The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase , 1995, Cell.
[37] J. Isner,et al. Apoptosis in human atherosclerosis and restenosis. , 1995, Circulation.
[38] A. Desmoulière,et al. Apoptosis participates in cellularity regulation during rat aortic intimal thickening. , 1995, The American journal of pathology.
[39] Y. Nishizuka. Protein kinase C and lipid signaling for sustained cellular responses , 1995, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[40] S. Meloche,et al. Angiotensin II Stimulates Tyrosine Phosphorylation of the Focal Adhesion-associated Protein Paxillin in Aortic Smooth Muscle Cells (*) , 1995, The Journal of Biological Chemistry.
[41] S. Keyse,et al. Tyrosine kinase inhibition: an approach to drug development. , 1995, Human & experimental toxicology.
[42] C. Turner,et al. Angiotensin II stimulation of rapid paxillin tyrosine phosphorylation correlates with the formation of focal adhesions in rat aortic smooth muscle cells. , 1995, Journal of cell science.
[43] K Y Hui,et al. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). , 1994, The Journal of biological chemistry.
[44] T. Okada,et al. Blockage of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinase. , 1994, The Journal of biological chemistry.
[45] A. Arcaro,et al. Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses. , 1993, The Biochemical journal.
[46] K. Shii,et al. Endothelin-1 stimulates tyrosine phosphorylation and the activities of two mitogen-activated protein kinases in cultured vascular smooth muscle cells , 1992, Journal of hypertension.
[47] K. Shii,et al. Angiotensin II stimulates two myelin basic protein/microtubule-associated protein 2 kinases in cultured vascular smooth muscle cells. , 1992, Circulation research.
[48] J. Testa,et al. A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region. , 1991, Science.
[49] J. Woodgett,et al. Molecular cloning and characterisation of a novel putative protein-serine kinase related to the cAMP-dependent and protein kinase C families. , 1991, European journal of biochemistry.
[50] K. Shii,et al. Vasoconstrictor‐induced protein‐tyrosine phosphorylation in cultured vascular smooth muscle cells , 1991, FEBS letters.
[51] B. Hemmings,et al. Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[52] S. Mizuno,et al. Specific inhibition of cytoplasmic protein tyrosine kinases by herbimycin A in vitro. , 1991, Biochemical pharmacology.
[53] A. Kraft,et al. Induction of the proto-oncogene c-jun by angiotensin II , 1990, Molecular and cellular biology.
[54] S. Mizuno,et al. Irreversible inhibition of v-src tyrosine kinase activity by herbimycin A and its abrogation by sulfhydryl compounds. , 1989, Biochemical and biophysical research communications.
[55] V. Dzau,et al. Induction of platelet-derived growth factor A-chain and c-myc gene expressions by angiotensin II in cultured rat vascular smooth muscle cells. , 1989, The Journal of clinical investigation.
[56] R. Alexander,et al. Angiotensin II induces c-fos mRNA in aortic smooth muscle. Role of Ca2+ mobilization and protein kinase C activation. , 1989, The Journal of biological chemistry.
[57] Y. Takai,et al. Stimulation of phospholipase C-mediated hydrolysis of phosphoinositides by adenosine 5'-triphosphate via P2-purinoceptors in cultured rat aortic vascular smooth muscle cells. , 1988, Japanese circulation journal.
[58] Y. Takai,et al. Angiotensin II induces expression of the c-fos gene through protein kinase C activation and calcium ion mobilization in cultured vascular smooth muscle cells. , 1988, Biochemical and biophysical research communications.
[59] M. Shibuya,et al. Genistein, a specific inhibitor of tyrosine-specific protein kinases. , 1987, The Journal of biological chemistry.