β‐Amyloid is transmitted via neuronal connections along axonal membranes

β‐amyloid plaque is a critical pathological feature of Alzheimer disease. Pathologic studies suggest that neurodegeneration may occur in a retrograde fashion from axon terminals near β‐amyloid plaques, and that plaque may spread through brain regions. However, there is no direct experimental evidence to show transmission of β‐amyloid.

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