Dysregulation of upstream binding factor-1 acetylation at K352 is linked to impaired ribosomal DNA transcription in Huntington's disease

[1]  Tom Moss,et al.  UBF levels determine the number of active ribosomal RNA genes in mammals , 2008, The Journal of cell biology.

[2]  I. Grummt,et al.  The epigenetics of rRNA genes: from molecular to chromosome biology. , 2008, Annual review of cell and developmental biology.

[3]  T. Moss,et al.  The splice variants of UBF differentially regulate RNA polymerase I transcription elongation in response to ERK phosphorylation , 2008, Nucleic acids research.

[4]  Ignazio Garaguso,et al.  Matrix layer sample preparation: An improved MALDI‐MS peptide analysis method for proteomic studies , 2008, Proteomics.

[5]  Andrew L Kung,et al.  Monoallele deletion of CBP leads to pericentromeric heterochromatin condensation through ESET expression and histone H3 (K9) methylation. , 2008, Human molecular genetics.

[6]  K. Park,et al.  Profiling of vitreous proteomes from proliferative diabetic retinopathy and nondiabetic patients , 2007, Proteomics.

[7]  M. Berciano,et al.  The giant fibrillar center: a nucleolar structure enriched in upstream binding factor (UBF) that appears in transcriptionally more active sensory ganglia neurons. , 2007, Journal of structural biology.

[8]  C. H. Lin,et al.  Mass spectrometric identification of phosphorylation sites of rRNA transcription factor upstream binding factor. , 2007, American journal of physiology. Cell physiology.

[9]  R. Ferrante,et al.  ESET/SETDB1 gene expression and histone H3 (K9) trimethylation in Huntington's disease , 2006, Proceedings of the National Academy of Sciences.

[10]  J. Cha,et al.  Mechanisms of Disease: histone modifications in Huntington's disease , 2006, Nature Clinical Practice Neurology.

[11]  T. Moss,et al.  Regulation of rRNA Synthesis in Human and Mouse Cells is Not Determined by Changes in Active Gene Count , 2006, Cell cycle.

[12]  B. Harper Huntington Disease , 2005, Journal of the Royal Society of Medicine.

[13]  R. Ferrante,et al.  Antioxidants modulate mitochondrial PKA and increase CREB binding to D-loop DNA of the mitochondrial genome in neurons. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[14]  R. Ferrante,et al.  Sodium phenylbutyrate prolongs survival and regulates expression of anti‐apoptotic genes in transgenic amyotrophic lateral sclerosis mice , 2005, Journal of neurochemistry.

[15]  Sui Huang,et al.  Upstream binding factor association induces large-scale chromatin decondensation. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[16]  K. Ghoshal,et al.  Role of Human Ribosomal RNA (rRNA) Promoter Methylation and of Methyl-CpG-binding Protein MBD2 in the Suppression of rRNA Gene Expression* , 2004, Journal of Biological Chemistry.

[17]  R. Neve,et al.  Sp1 and Sp3 Are Oxidative Stress-Inducible, Antideath Transcription Factors in Cortical Neurons , 2003, The Journal of Neuroscience.

[18]  R. Ferrante,et al.  Histone deacetylase inhibitors prevent oxidative neuronal death independent of expanded polyglutamine repeats via an Sp1-dependent pathway , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[19]  K. Fischbeck,et al.  Histone deacetylase inhibitors reduce polyglutamine toxicity , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[20]  S. Tsuji,et al.  Interaction between neuronal intranuclear inclusions and promyelocytic leukemia protein nuclear and coiled bodies in CAG repeat diseases. , 2001, The American journal of pathology.

[21]  D. Housman,et al.  Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila , 2001, Nature.

[22]  J. Catania,et al.  The role of acetylation in rDNA transcription. , 2001, Nucleic acids research.

[23]  David Tollervey,et al.  The function and synthesis of ribosomes , 2001, Nature Reviews Molecular Cell Biology.

[24]  K. Fischbeck,et al.  Polyglutamine and CBP: Fatal attraction? , 2001, Nature Medicine.

[25]  James M. Olson,et al.  Therapeutic opportunities in polyglutamine disease , 2001, Nature Medicine.

[26]  C A Ross,et al.  Interference by Huntingtin and Atrophin-1 with CBP-Mediated Transcription Leading to Cellular Toxicity , 2001, Science.

[27]  N. Galjart,et al.  Characterisation of transcriptionally active and inactive chromatin domains in neurons. , 2000, Journal of cell science.

[28]  M. MacDonald,et al.  Dominant phenotypes produced by the HD mutation in STHdh(Q111) striatal cells. , 2000, Human molecular genetics.

[29]  M. Faubladier,et al.  Competitive recruitment of CBP and Rb-HDAC regulates UBF acetylation and ribosomal transcription. , 2000, Molecular cell.

[30]  D. Housman,et al.  The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[31]  E. Wintersberger,et al.  Histone Deacetylase 1 Can Repress Transcription by Binding to Sp1 , 1999, Molecular and Cellular Biology.

[32]  S. W. Davies,et al.  Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice , 1996, Cell.

[33]  R. Hannan,et al.  Overexpression of the transcription factor UBF1 is sufficient to increase ribosomal DNA transcription in neonatal cardiomyocytes: implications for cardiac hypertrophy. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[34]  L. Rothblum,et al.  Identification of two forms of the RNA polymerase I transcription factor UBF. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[35]  H. Zoghbi,et al.  Glutamine repeats and neurodegeneration. , 2000, Annual review of neuroscience.