Apoptosis and G2/M cell cycle arrest induced by a timosaponin A3 from Anemarrhena asphodeloides Bunge on AsPC-1 pancreatic cancer cells.

[1]  Hong Jiang,et al.  Ketamine induces neuronal apoptosis and cognitive disorder via miR-199a-5p/HIF-1α in neonatal rats , 2017, Molecular & Cellular Toxicology.

[2]  A. Wongnoppavich,et al.  The effect of purple rice (Oryza sativa L. indica) extract on the inflammatory response in a colon cancer cell line and dextran sulfate-induced tumor promotion in the rat colon , 2017, Molecular & Cellular Toxicology.

[3]  H. Koo,et al.  Gamma irradiation-induced liver injury and its amelioration by red ginseng extract , 2017, Molecular & Cellular Toxicology.

[4]  P. Wee,et al.  Epidermal Growth Factor Receptor Cell Proliferation Signaling Pathways , 2017, Cancers.

[5]  Jeong-Hwa Lee,et al.  BIS overexpression does not affect the sensitivity of HEK 293T cells against apoptosis , 2017, Molecular & Cellular Toxicology.

[6]  P. Casey,et al.  Inhibition of Isoprenylcysteine Carboxylmethyltransferase Induces Cell-Cycle Arrest and Apoptosis through p21 and p21-Regulated BNIP3 Induction in Pancreatic Cancer , 2017, Molecular Cancer Therapeutics.

[7]  Yu Jin Lee,et al.  Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways. , 2016, Bioorganic & medicinal chemistry letters.

[8]  Lei He,et al.  Ortho-topolin riboside induces apoptosis in Acute myeloid leukemia HL-60 cells , 2016, Molecular & Cellular Toxicology.

[9]  Dongju Lin,et al.  Determination of the chemical constituents of the different processed products of Anemarrhena asphodeloides Rhizomes by high-performance liquid chromatography quadrupole time-of-flight mass spectrometry. , 2016, Biomedical chromatography : BMC.

[10]  M. Yashiro,et al.  Molecular targets for the treatment of pancreatic cancer: Clinical and experimental studies. , 2016, World journal of gastroenterology.

[11]  Minhui Li,et al.  The genus Anemarrhena Bunge: A review on ethnopharmacology, phytochemistry and pharmacology. , 2014, Journal of ethnopharmacology.

[12]  R. Hruban,et al.  Pancreatic cancer , 2011, The Lancet.

[13]  D. Levy,et al.  STAT3 plays a critical role in KRAS-induced pancreatic tumorigenesis. , 2011, Cancer research.

[14]  Dongho Lee,et al.  Cytotoxic and antineoplastic activity of timosaponin A-III for human colon cancer cells. , 2011, Journal of natural products.

[15]  K. Unfried,et al.  c-Src-mediated activation of Erk1/2 is a reaction of epithelial cells to carbon nanoparticle treatment and may be a target for a molecular preventive strategy , 2010, Biological chemistry.

[16]  You Jin Park,et al.  Global transcriptome analysis of the Escherichia coli O157 response to Houttuynia Cordata Thunb , 2010 .

[17]  M. Washington,et al.  Targeted Inhibition of Src Kinase Signaling Attenuates Pancreatic Tumorigenesis , 2010, Molecular Cancer Therapeutics.

[18]  N. Lemoine,et al.  Pancreatic cancer: molecular pathogenesis and new therapeutic targets , 2009, Nature Reviews Gastroenterology &Hepatology.

[19]  C. Der,et al.  Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer , 2007, Oncogene.

[20]  J. Pouysségur,et al.  The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition , 2007, Oncogene.

[21]  B. Aggarwal,et al.  Targeting Signal‐Transducer‐and‐Activator‐of‐Transcription‐3 for Prevention and Therapy of Cancer , 2006, Annals of the New York Academy of Sciences.

[22]  J. Parsons,et al.  Src family kinases, key regulators of signal transduction , 2004, Oncogene.

[23]  B. Wiedenmann,et al.  Activated signal transducer and activator of transcription 3 (STAT3) supports the malignant phenotype of human pancreatic cancer. , 2003, Gastroenterology.

[24]  G. Johnson,et al.  Mitogen-Activated Protein Kinase Pathways Mediated by ERK, JNK, and p38 Protein Kinases , 2002, Science.

[25]  I. Kerr,et al.  Jaks and Stats in signaling by the cytokine receptor superfamily. , 1995, Trends in genetics : TIG.

[26]  K. Bian,et al.  [Effects of four kinds of Chinese medicine monomer on growth of PANC-1 xenograft tumor and studying of molecular mechanism]. , 2013, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.

[27]  J. Avruch,et al.  Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTOR , 2000, Current Biology.