Different approaches to volume assessment of lymph nodes in computer tomography scans of head and neck squamous cell carcinoma in comparison with a real gold standard

Volume assessment in head and neck squamous cell carcinoma (HNSCC) is becoming a more and more clinical important parameter, especially in treatment planning and response control. Various authors showed a significant impact of tumour volume on treatment outcome and local control. Regarding the increasing impact of induction chemotherapy and primary chemoradiation on HNSCC, the need for an adequate measuring tool to judge treatment response becomes obvious. This study was performed to compare the momentary ‘gold standard’, the diameter‐based approach, and tumour volume assessment in HNSCC with approaches based on segmentation algorithms in computer tomography (CT) scans.

[1]  Heinz-Otto Peitgen,et al.  Ground Truth in MS Lesion Volumetry - A Phantom Study , 2003, MICCAI.

[2]  S. Hughes.  Archimedes revisited: a faster, better, cheaper method of accurately measuring the volume of small objects , 2005 .

[3]  Bernhard Preim,et al.  Interactive Visualization for Neck-Dissection Planning , 2005, EuroVis.

[4]  H D Thames,et al.  The tumor volume and clonogen number relationship: tumor control predictions based upon tumor volume estimates derived from computed tomography. , 1995, International journal of radiation oncology, biology, physics.

[5]  Jeffrey N. Myers,et al.  Functional anatomy of the lymphatic drainage system of the upper aerodigestive tract and its role in metastasis of squamous cell carcinoma , 2003, Head & neck.

[6]  A G Sorensen,et al.  Comparison of diameter and perimeter methods for tumor volume calculation. , 2001, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[7]  Arnold Knijn,et al.  EUROCARE-4. Survival of cancer patients diagnosed in 1995-1999. Results and commentary. , 2009, European journal of cancer.

[8]  Rick Chappell,et al.  Primary tumor volume of nasopharyngeal carcinoma: prognostic significance for local control. , 2004, International journal of radiation oncology, biology, physics.

[9]  B Preim,et al.  [Three-dimensional visualization for preoperative planning and evaluation in head and neck surgery]. , 2009, Laryngo- rhino- otologie.

[10]  M. Reiser,et al.  Volumetrie von Metastasen beim Nierenzellkarzinom , 2008, Der Radiologe.

[11]  M F Reiser,et al.  [Volumetry of metastases from renal cell carcinoma: comparison with the RECIST criteria]. , 2008, Der Radiologe.

[12]  R Hadi,et al.  Quantitative tumor volume VS TNM staging: the impact on prognosis in head and neck cancer. , 2010, The Gulf journal of oncology.

[13]  D. Wazer,et al.  The influence of quantitative tumor volume measurements on local control in advanced head and neck cancer using concomitant boost accelerated superfractionated irradiation. , 1995, International journal of radiation oncology, biology, physics.

[14]  L. Schwartz,et al.  New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). , 2009, European journal of cancer.

[15]  Bernhard Preim,et al.  The Tumor Therapy Manager - Design, Refinement and Clinical Use of a Software Product for ENT Surgery Planning and Documentation , 2011, IPCAI.

[16]  Mu-Kuan Chen,et al.  Better prediction of prognosis for patients with nasopharyngeal carcinoma using primary tumor volume , 2004, Cancer.

[17]  D. Chua,et al.  Volumetric analysis of tumor extent in nasopharyngeal carcinoma and correlation with treatment outcome. , 1997, International journal of radiation oncology, biology, physics.

[18]  V. Chong,et al.  Tumour volume measurement in head and neck cancer , 2007, Cancer imaging : the official publication of the International Cancer Imaging Society.

[19]  Hans-Peter Meinzer,et al.  Empirical discrepancy measures for the evaluation of segmentation results , 2004, CARS.