Genome-wide identification of essential genes in Mycobacterium intracellulare by transposon sequencing — Implication for metabolic remodeling

[1]  William R. Harcombe,et al.  Genomewide Assessment of Mycobacterium tuberculosis Conditionally Essential Metabolic Pathways , 2019, mSystems.

[2]  R. Baker,et al.  A Lysine Acetyltransferase Contributes to the Metabolic Adaptation to Hypoxia in Mycobacterium tuberculosis. , 2018, Cell chemical biology.

[3]  M. Chase,et al.  TnSeq of Mycobacterium tuberculosis clinical isolates reveals strain-specific antibiotic liabilities , 2018, PLoS pathogens.

[4]  Paul Stoodley,et al.  Targeting microbial biofilms: current and prospective therapeutic strategies , 2017, Nature Reviews Microbiology.

[5]  P. Kumari,et al.  Protein kinase G confers survival advantage to Mycobacterium tuberculosis during latency-like conditions , 2017, The Journal of Biological Chemistry.

[6]  T. Parish,et al.  Mutations in MmpL3 alter membrane potential, hydrophobicity and antibiotic susceptibility in Mycobacterium smegmatis. , 2017, Microbiology.

[7]  F. Hsu,et al.  The Mycobacterium tuberculosis MmpL11 Cell Wall Lipid Transporter Is Important for Biofilm Formation, Intracellular Growth, and Nonreplicating Persistence , 2017, Infection and Immunity.

[8]  U. Sauer,et al.  PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis , 2017, PLoS pathogens.

[9]  S. Chou,et al.  Regulation of Inducible Potassium Transporter KdpFABC by the KdpD/KdpE Two-Component System in Mycobacterium smegmatis , 2017, Front. Microbiol..

[10]  S. Matsumoto,et al.  Effects of nutritional and ambient oxygen condition on biofilm formation in Mycobacterium avium subsp. hominissuis via altered glycolipid expression , 2017, Scientific Reports.

[11]  G. Pazour,et al.  Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness , 2017, Scientific Reports.

[12]  Thomas R. Ioerger,et al.  Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis , 2017, mBio.

[13]  S. Sarsaiya,et al.  Prevalence and species spectrum of both pulmonary and extrapulmonary nontuberculous mycobacteria isolates at a tertiary care center , 2016, International journal of mycobacteriology.

[14]  R. Musters,et al.  The ESX-5 System of Pathogenic Mycobacteria Is Involved In Capsule Integrity and Virulence through Its Substrate PPE10 , 2016, PLoS pathogens.

[15]  Satoshi Mitarai,et al.  Epidemiology of Pulmonary Nontuberculous Mycobacterial Disease, Japan , 2016, Emerging infectious diseases.

[16]  Deepak L. Bhatt,et al.  Thiol reductive stress induces cellulose-anchored biofilm formation in Mycobacterium tuberculosis , 2016, Nature Communications.

[17]  T. Hirai,et al.  Impact of industrial structure and soil exposure on the regional variations in pulmonary nontuberculous mycobacterial disease prevalence , 2016, International journal of mycobacteriology.

[18]  E. Rubin,et al.  Leveraging Advances in Tuberculosis Diagnosis and Treatment to Address Nontuberculous Mycobacterial Disease , 2016, Emerging infectious diseases.

[19]  B. Ueberheide,et al.  Separable roles for Mycobacterium tuberculosis ESX-3 effectors in iron acquisition and virulence , 2016, Proceedings of the National Academy of Sciences.

[20]  Thomas R. Ioerger,et al.  TRANSIT - A Software Tool for Himar1 TnSeq Analysis , 2015, PLoS Comput. Biol..

[21]  A. Upadhyay,et al.  Partial Saturation of Menaquinone in Mycobacterium tuberculosis: Function and Essentiality of a Novel Reductase, MenJ , 2015, ACS central science.

[22]  Yusuke Minato,et al.  Mycobacterium tuberculosis Folate Metabolism and the Mechanistic Basis for para-Aminosalicylic Acid Susceptibility and Resistance , 2015, Antimicrobial Agents and Chemotherapy.

[23]  A. Kierzek,et al.  Lipid metabolism and Type VII secretion systems dominate the genome scale virulence profile of Mycobacterium tuberculosis in human dendritic cells , 2015, BMC Genomics.

[24]  Alyaa M. Abdel-Haleem,et al.  Essential Role of the ESX-5 Secretion System in Outer Membrane Permeability of Pathogenic Mycobacteria , 2015, PLoS genetics.

[25]  L. Amzel,et al.  A Redox Regulatory System Critical for Mycobacterial Survival in Macrophages and Biofilm Development , 2015, PLoS pathogens.

[26]  Douwe Molenaar,et al.  Genome-Wide Transposon Mutagenesis Indicates that Mycobacterium marinum Customizes Its Virulence Mechanisms for Survival and Replication in Different Hosts , 2015, Infection and Immunity.

[27]  E. Wolfson,et al.  Bacterial Flagella: Twist and Stick, or Dodge across the Kingdoms , 2015, PLoS pathogens.

[28]  C. Jourlin-Castelli,et al.  Gram-negative bacteria can also form pellicles. , 2014, Environmental microbiology reports.

[29]  Aldert L. Zomer,et al.  From microbial gene essentiality to novel antimicrobial drug targets , 2014, BMC Genomics.

[30]  R. Schwartz,et al.  Reference-free inference of tumor phylogenies from single-cell sequencing data , 2014, 2014 IEEE 4th International Conference on Computational Advances in Bio and Medical Sciences (ICCABS).

[31]  S. Carr,et al.  Mycobacterial Esx-3 Requires Multiple Components for Iron Acquisition , 2014, mBio.

[32]  Thomas R. Ioerger,et al.  Tryptophan Biosynthesis Protects Mycobacteria from CD4 T-Cell-Mediated Killing , 2013, Cell.

[33]  S. Sreevatsan,et al.  Mannosylated Lipoarabinomannans from Mycobacterium Avium Subsp. Paratuberculosis Alters the Inflammatory Response by Bovine Macrophages and Suppresses Killing of Mycobacterium Avium Subsp. Avium Organisms , 2013, PloS one.

[34]  K. Holt,et al.  Out-of-Africa migration and Neolithic co-expansion of Mycobacterium tuberculosis with modern humans , 2013, Nature Genetics.

[35]  S. Akhtar,et al.  Nitrite Reductase NirBD Is Induced and Plays an Important Role during In Vitro Dormancy of Mycobacterium tuberculosis , 2013, Journal of bacteriology.

[36]  A. Camilli,et al.  Transposon insertion sequencing: a new tool for systems-level analysis of microorganisms , 2013, Nature Reviews Microbiology.

[37]  K. Rhee,et al.  Multifunctional essentiality of succinate metabolism in adaptation to hypoxia in Mycobacterium tuberculosis , 2013, Proceedings of the National Academy of Sciences.

[38]  Taroh Kinoshita,et al.  Critical Roles for Lipomannan and Lipoarabinomannan in Cell Wall Integrity of Mycobacteria and Pathogenesis of Tuberculosis , 2013, mBio.

[39]  J. Mckinney,et al.  Mycobacterium tuberculosis Requires Phosphate-Responsive Gene Regulation To Resist Host Immunity , 2012, Infection and Immunity.

[40]  Thomas R. Ioerger,et al.  Global Assessment of Genomic Regions Required for Growth in Mycobacterium tuberculosis , 2012, PLoS pathogens.

[41]  Vinod Nair,et al.  SQ109 Targets MmpL3, a Membrane Transporter of Trehalose Monomycolate Involved in Mycolic Acid Donation to the Cell Wall Core of Mycobacterium tuberculosis , 2012, Antimicrobial Agents and Chemotherapy.

[42]  Thomas R. Ioerger,et al.  High-Resolution Phenotypic Profiling Defines Genes Essential for Mycobacterial Growth and Cholesterol Catabolism , 2011, PLoS pathogens.

[43]  L. Dijkhuizen,et al.  The Steroid Catabolic Pathway of the Intracellular Pathogen Rhodococcus equi Is Important for Pathogenesis and a Target for Vaccine Development , 2011, PLoS pathogens.

[44]  Marcel Martin Cutadapt removes adapter sequences from high-throughput sequencing reads , 2011 .

[45]  Paul Stothard,et al.  Interactive microbial genome visualization with GView , 2010, Bioinform..

[46]  Sabine Ehrt,et al.  Gluconeogenic carbon flow of tricarboxylic acid cycle intermediates is critical for Mycobacterium tuberculosis to establish and maintain infection , 2010, Proceedings of the National Academy of Sciences.

[47]  C. Vilchèze,et al.  An Anaerobic-Type α-Ketoglutarate Ferredoxin Oxidoreductase Completes the Oxidative Tricarboxylic Acid Cycle of Mycobacterium tuberculosis , 2009, PLoS pathogens.

[48]  W. Bishai,et al.  Phosphate depletion: a novel trigger for Mycobacterium tuberculosis persistence. , 2009, The Journal of infectious diseases.

[49]  C. Bewley,et al.  Dequalinium, a New Inhibitor of Mycobacterium tuberculosis Mycothiol Ligase Identified by High-Throughput Screening , 2009, Journal of biomolecular screening.

[50]  Cole Trapnell,et al.  Ultrafast and memory-efficient alignment of short DNA sequences to the human genome , 2009, Genome Biology.

[51]  F. Levillain,et al.  Capsular glucan and intracellular glycogen of Mycobacterium tuberculosis: biosynthesis and impact on the persistence in mice , 2008, Molecular microbiology.

[52]  David Alland,et al.  Mycothiol biosynthesis is essential for ethionamide susceptibility in Mycobacterium tuberculosis , 2008, Molecular microbiology.

[53]  James A. Raleigh,et al.  Tuberculous Granulomas Are Hypoxic in Guinea Pigs, Rabbits, and Nonhuman Primates , 2008, Infection and Immunity.

[54]  Y. Nishiuchi,et al.  The recovery of Mycobacterium avium-intracellulare complex (MAC) from the residential bathrooms of patients with pulmonary MAC. , 2007, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[55]  N. Ampel Diagnosis, Treatment, and Prevention of Nontuberculous Mycobacterial Diseases , 2007 .

[56]  Robert Horsburgh,et al.  An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases. , 2007, American journal of respiratory and critical care medicine.

[57]  Vojo Deretic,et al.  Mechanisms of action of isoniazid , 2006, Molecular microbiology.

[58]  S. Butler-Wu,et al.  Identification of substrates of the Mycobacterium tuberculosis proteasome , 2006, The EMBO journal.

[59]  Ping Chen,et al.  Synergistic interactions of SQ109, a new ethylene diamine, with front-line antitubercular drugs in vitro. , 2006, The Journal of antimicrobial chemotherapy.

[60]  Joyoti Basu,et al.  The serine/threonine kinase PknB of Mycobacterium tuberculosis phosphorylates PBPA, a penicillin-binding protein required for cell division. , 2006, Microbiology.

[61]  L. Kremer,et al.  GroEL1: A Dedicated Chaperone Involved in Mycolic Acid Biosynthesis during Biofilm Formation in Mycobacteria , 2005, Cell.

[62]  Makoto Suematsu,et al.  Variant tricarboxylic acid cycle in Mycobacterium tuberculosis: identification of alpha-ketoglutarate decarboxylase. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[63]  E. Muñoz-Elías,et al.  Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence , 2005, Nature Medicine.

[64]  Philip S. Stewart,et al.  Stratified Growth in Pseudomonas aeruginosa Biofilms , 2004, Applied and Environmental Microbiology.

[65]  C. Nathan,et al.  The Proteasome of Mycobacterium tuberculosis Is Required for Resistance to Nitric Oxide , 2003, Science.

[66]  W. Jacobs,et al.  Identification of a Regulated Alkaline Phosphatase, a Cell Surface-Associated Lipoprotein, in Mycobacterium smegmatis , 2003, Journal of bacteriology.

[67]  P. Stoodley,et al.  Developmental regulation of microbial biofilms. , 2002, Current opinion in biotechnology.

[68]  James C. Sacchettini,et al.  Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase , 2000, Nature.

[69]  J. Mekalanos,et al.  Hyperactive transposase mutants of the Himar1 mariner transposon. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[70]  B. Parker,et al.  Epidemiology of infection by nontuberculous mycobacteria. Mycobacterium avium, Mycobacterium intracellulare, and Mycobacterium scrofulaceum in acid, brown-water swamps of the southeastern United States and their association with environmental variables. , 1992, The American review of respiratory disease.

[71]  W. Jacobs,et al.  Introduction of foreign DNA into mycobacteria using a shuttle phasmid , 1987, Nature.

[72]  Yongge Liu,et al.  Mechanisms of resistance to delamanid, a drug for Mycobacterium tuberculosis. , 2018, Tuberculosis.

[73]  P. V. van Helden,et al.  Isolation of DNA from Mycobacterium tubercolosis. , 2001, Methods in molecular medicine.

[74]  H. Nikaido,et al.  The envelope of mycobacteria. , 1995, Annual review of biochemistry.