A large-scale analysis of targeted metabolomics data from heterogeneous biological samples provides insights into metabolite dynamics

[1]  Ho-Joon Lee,et al.  Macrophage Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer , 2018, bioRxiv.

[2]  Ji-Hoon Cho,et al.  Isotope Labeling-Assisted Evaluation of Hydrophilic and Hydrophobic Liquid Chromatograph-Mass Spectrometry for Metabolomics Profiling. , 2018, Analytical chemistry.

[3]  Dafydd G. Thomas,et al.  Menin regulates the serine biosynthetic pathway in Ewing sarcoma , 2018, The Journal of pathology.

[4]  David S. Wishart,et al.  MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis , 2018, Nucleic Acids Res..

[5]  Oleksandr Moskalenko,et al.  SECIMTools: a suite of metabolomics data analysis tools , 2018, BMC Bioinformatics.

[6]  C. Sander,et al.  A Landscape of Metabolic Variation across Tumor Types. , 2018, Cell systems.

[7]  Ho-Joon Lee,et al.  Mutant p53R270H drives altered metabolism and increased invasion in pancreatic ductal adenocarcinoma , 2018, JCI insight.

[8]  Ho-Joon Lee,et al.  Mutant p 53 R 270 H drives altered metabolism and increased invasion in pancreatic ductal adenocarcinoma , 2018 .

[9]  Bo Li,et al.  NOREVA: normalization and evaluation of MS-based metabolomics data , 2017, Nucleic Acids Res..

[10]  Kwanjeera Wanichthanarak,et al.  Metabox: A Toolbox for Metabolomic Data Analysis, Interpretation and Integrative Exploration , 2017, PloS one.

[11]  Juntuo Zhou,et al.  Strategies for large-scale targeted metabolomics quantification by liquid chromatography-mass spectrometry. , 2016, The Analyst.

[12]  A. Weljie,et al.  Comprehensive optimization of LC–MS metabolomics methods using design of experiments (COLMeD) , 2016, Metabolomics.

[13]  Choon Nam Ong,et al.  HILIC-MS for metabolomics: An attractive and complementary approach to RPLC-MS. , 2016, Mass spectrometry reviews.

[14]  L. Cantley,et al.  Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion , 2016, Nature.

[15]  Caroline H. Johnson,et al.  Metabolomics: beyond biomarkers and towards mechanisms , 2016, Nature Reviews Molecular Cell Biology.

[16]  D. Wishart Emerging applications of metabolomics in drug discovery and precision medicine , 2016, Nature Reviews Drug Discovery.

[17]  Ralf Tautenhahn,et al.  Toward 'omic scale metabolite profiling: a dual separation-mass spectrometry approach for coverage of lipid and central carbon metabolism. , 2013, Analytical chemistry.

[18]  S. Sandberg,et al.  A systematic review of data on biological variation for alanine aminotransferase, aspartate aminotransferase and γ-glutamyl transferase , 2013, Clinical chemistry and laboratory medicine.

[19]  C. Barbas,et al.  LC-MS metabolomics of polar compounds. , 2012, Bioanalysis.

[20]  J. Asara,et al.  A positive/negative ion–switching, targeted mass spectrometry–based metabolomics platform for bodily fluids, cells, and fresh and fixed tissue , 2012, Nature Protocols.

[21]  G. Siuzdak,et al.  Innovation: Metabolomics: the apogee of the omics trilogy , 2012, Nature Reviews Molecular Cell Biology.

[22]  B. Buszewski,et al.  Hydrophilic interaction liquid chromatography (HILIC)—a powerful separation technique , 2011, Analytical and Bioanalytical Chemistry.

[23]  J. Thomas-Oates,et al.  Metabolomic applications of HILIC-LC-MS. , 2010, Mass spectrometry reviews.

[24]  Yuqin Wang,et al.  Targeted metabolomics for biomarker discovery. , 2010, Angewandte Chemie.

[25]  J. Rabinowitz,et al.  Analytical strategies for LC-MS-based targeted metabolomics. , 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[26]  Zhigang Hao,et al.  Impact of column temperature and mobile phase components on selectivity of hydrophilic interaction chromatography (HILIC). , 2008, Journal of separation science.

[27]  R. A. van den Berg,et al.  Centering, scaling, and transformations: improving the biological information content of metabolomics data , 2006, BMC Genomics.

[28]  P. Oefner,et al.  Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. Preface , 2002 .