P53 mediates ceramide-induced apoptosis in SKN-SH cells

[1]  M. Nikolova-Karakashian,et al.  Activation of sphingolipid turnover and chronic generation of ceramide and sphingosine in liver during aging , 2000, Mechanisms of Ageing and Development.

[2]  E. Yonish-Rouach,et al.  Mechanisms of p53-induced apoptosis: in search of genes which are regulated during p53-mediated cell death. , 1998, Toxicology letters.

[3]  G. Dbaibo,et al.  Distinct sites of action of Bcl-2 and Bcl-xL in the ceramide pathway of apoptosis. , 1998, The Biochemical journal.

[4]  A. Khar,et al.  Selective involvement of caspase‐3 in ceramide induced apoptosis in AK‐5 tumor cells , 1998, FEBS letters.

[5]  R. Kolesnick,et al.  Signal transduction of stress via ceramide. , 1998, The Biochemical journal.

[6]  G. Dbaibo,et al.  p53-dependent ceramide response to genotoxic stress. , 1998, The Journal of clinical investigation.

[7]  A. W. Murray,et al.  Neurotrophic Factors Prevent Ceramide‐Induced Apoptosis Downstream of c‐Jun N‐Terminal Kinase Activation in PC12 Cells , 1998, Journal of neurochemistry.

[8]  Y Agid,et al.  Mitochondrial Free Radical Signal in Ceramide‐Dependent Apoptosis: A Putative Mechanism for Neuronal Death in Parkinson's Disease , 1997, Journal of neurochemistry.

[9]  S. Kim,et al.  Sphingomyelinase activity is enhanced in cerebral cortex of senescence-accelerated mouse-P/10 with advancing age. , 1997, Biochemical and biophysical research communications.

[10]  J. Coggins,et al.  The study of cell-death proteins in the outer mitochondrial membrane by chemical cross-linking. , 1997, The Biochemical journal.

[11]  Y. Hannun,et al.  Bcl‐2 antagonizes apoptotic cell death induced by two new ceramide analogues , 1997, FEBS letters.

[12]  John Calvin Reed Double identity for proteins of the Bcl-2 family , 1997, Nature.

[13]  G. Laurent,et al.  Influence of Bcl-2 overexpression on the ceramide pathway in daunorubicin-induced apoptosis of leukemic cells , 1997, Oncogene.

[14]  M. Moskowitz,et al.  Expression of a Dominant Negative Mutant of Interleukin-1β Converting Enzyme in Transgenic Mice Prevents Neuronal Cell Death Induced by Trophic Factor Withdrawal and Ischemic Brain Injury , 1997, The Journal of experimental medicine.

[15]  A. Levine p53, the Cellular Gatekeeper for Growth and Division , 1997, Cell.

[16]  A. W. Murray,et al.  Ceramide induces apoptosis in PC12 cells , 1997, FEBS letters.

[17]  N. Miyasaka,et al.  Ceramide induces apoptosis via CPP32 activation , 1996, FEBS letters.

[18]  Junying Yuan,et al.  Human ICE/CED-3 Protease Nomenclature , 1996, Cell.

[19]  C. Borner,et al.  Bcl-2 interrupts the ceramide-mediated pathway of cell death. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[20]  M. Oren,et al.  Cell type‐specific inhibition of p53‐mediated apoptosis by mdm2. , 1996, The EMBO journal.

[21]  John Calvin Reed,et al.  Proapoptotic Protein Bax Heterodimerizes with Bcl-2 and Homodimerizes with Bax via a Novel Domain (BH3) Distinct from BH1 and BH2 (*) , 1996, The Journal of Biological Chemistry.

[22]  E. White,et al.  The E1B 19K protein blocks apoptosis by interacting with and inhibiting the p53-inducible and death-promoting Bax protein. , 1996, Genes & development.

[23]  Y. Agid,et al.  Ceramide Induces Apoptosis in Cultured Mesencephalic Neurons , 1996, Journal of neurochemistry.

[24]  A. Bielawska,et al.  Role of Ceramide in Cellular Senescence (*) , 1995, The Journal of Biological Chemistry.

[25]  S. Korsmeyer,et al.  Bax-Deficient Mice with Lymphoid Hyperplasia and Male Germ Cell Death , 1995, Science.

[26]  Z. Oltvai,et al.  Multiple Bcl-2 family members demonstrate selective dimerizations with Bax. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[27]  Seamus J. Martin,et al.  Protease activation during apoptosis: Death by a thousand cuts? , 1995, Cell.

[28]  V. Rotter,et al.  Direct involvement of p53 in programmed cell death of oligodendrocytes. , 1995, The EMBO journal.

[29]  S. Korsmeyer,et al.  Bad, a heterodimeric partner for Bcl-xL and Bcl-2, displaces bax and promotes cell death , 1995, Cell.

[30]  T. Graeber,et al.  Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status , 1994, Molecular and cellular biology.

[31]  S. Korsmeyer,et al.  Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death , 1993, Cell.

[32]  C. Purdie,et al.  Thymocyte apoptosis induced by p53-dependent and independent pathways , 1993, Nature.

[33]  P. W. Mesner,et al.  Nerve growth factor withdrawal-induced cell death in neuronal PC12 cells resembles that in sympathetic neurons , 1992, The Journal of cell biology.

[34]  M. M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. , 1976, Analytical biochemistry.

[35]  U. K. Laemmli,et al.  Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 , 1970, Nature.

[36]  N. Thornberry The caspase family of cysteine proteases. , 1997, British medical bulletin.

[37]  T. Deckwerth,et al.  Molecular mechanisms of developmental neuronal death. , 1993, Annual review of neuroscience.