Is there a role for positron emission tomography with 18F‐fluorodeoxyglucose in the initial staging of nodal negative oral and oropharyngeal squamous cell carcinoma

The aim of our study was to assess the value of positron emission tomography (PET) with 18F‐fluorodeoxyglucose (FDG) for the staging of clinically nodal negative necks in oral and oropharyngeal squamous cell carcinoma (SCC) using sentinel lymph node (SLN) biopsy and elective neck dissection (END) as “gold standard” for comparison.

[1]  A. Leonard,et al.  Correlation between prognosis and degree of lymph node involvement in carcinoma of the oral cavity. , 1978, American journal of surgery.

[2]  R M Byers,et al.  Rationale for elective modified neck dissection. , 1988, Head & neck surgery.

[3]  J. Shah,et al.  Patterns of cervical lymph node metastasis from squamous carcinomas of the upper aerodigestive tract. , 1990, American journal of surgery.

[4]  E Abemayor,et al.  Positron emission tomography: A new, precise imaging modality for detection of primary head and neck tumors and assessment of cervical adenopathy , 1992, The Laryngoscope.

[5]  R. Lufkin,et al.  Use of positron emission tomography with fluorodeoxyglucose in patients with extracranial head and neck cancers. , 1994, Cancer.

[6]  T G Turkington,et al.  Performance characteristics of a whole-body PET scanner. , 1994, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[7]  K. Geisinger,et al.  A comparative diagnostic study of head and neck nodal metastases using positron emission tomography , 1995, The Laryngoscope.

[8]  S. Barrington,et al.  Speech-related visualization of laryngeal muscles with fluorine-18-FDG. , 1996, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[9]  G. Snow,et al.  The Incidence of Micrometastases in Neck Dissection Specimens Obtained From Elective Neck Dissections , 1996, The Laryngoscope.

[10]  R. Talamini,et al.  Analysis of prognostic factors for recurrence after neck dissection. , 1996, Archives of otolaryngology--head & neck surgery.

[11]  U. Brinck,et al.  Detection of nodal micrometastases in head and neck cancer by serial sectioning and immunostaining. , 1996, Oncology.

[12]  M. F. Williams,et al.  Detection of cervical metastasis. A meta-analysis comparing computed tomography with physical examination. , 1997, Archives of otolaryngology--head & neck surgery.

[13]  K. Kopecky,et al.  Comparison of ultrasound‐fine needle aspiration and computed tomography in patients undergoing elective neck dissection , 1997, Head & neck.

[14]  M. Wax,et al.  Positron Emission Tomography in the Evaluation of the N0 Neck , 1998, The Laryngoscope.

[15]  D. Dunaway,et al.  A suggested method for sentinel node biopsy in squamous cell carcinoma of the head and neck , 1999, Head & neck.

[16]  H. Hamakawa,et al.  Histological study on pN upgrading of oral cancer , 2000, Virchows Archiv.

[17]  D. Krag,et al.  Sentinel Lymph Node Radiolocalization in Head and Neck Squamous Cell Carcinoma , 2000, The Laryngoscope.

[18]  J. Benson,et al.  Classification of isolated tumor cells and micrometastasis , 2000, Cancer.

[19]  S. Stoeckli,et al.  Histopathological Features of Occult Metastasis Detected by Sentinel Lymph Node Biopsy in Oral and Oropharyngeal Squamous Cell Carcinoma , 2002, The Laryngoscope.