Antimicrobial peptides in health and disease.

Microbes surround us. However, most of the time we are unaware of them. Our epithelial surfaces, which provide the physical barrier separating us from the environment, are usually free of signs of ...

[1]  Ji Ming Wang,et al.  Ll-37, the Neutrophil Granule–And Epithelial Cell–Derived Cathelicidin, Utilizes Formyl Peptide Receptor–Like 1 (Fprl1) as a Receptor to Chemoattract Human Peripheral Blood Neutrophils, Monocytes, and T Cells , 2000, The Journal of experimental medicine.

[2]  S. Akira,et al.  Toll-like receptors: critical proteins linking innate and acquired immunity , 2001, Nature Immunology.

[3]  D. Barra,et al.  Effect of glucocorticoids on the synthesis of antimicrobial peptides in amphibian skin , 1997, FEBS letters.

[4]  Jesse D. Walters,et al.  Discovery of five conserved β-defensin gene clusters using a computational search strategy , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[5]  M. Zasloff.  Antimicrobial peptides of multicellular organisms , 2002, Nature.

[6]  H. Wigzell,et al.  The Expression of the Gene Coding for the Antibacterial Peptide LL-37 Is Induced in Human Keratinocytes during Inflammatory Disorders* , 1997, The Journal of Biological Chemistry.

[7]  J. Schröder,et al.  A peptide antibiotic from human skin , 1997, Nature.

[8]  R. Gennaro,et al.  Structural features and biological activities of the cathelicidin-derived antimicrobial peptides. , 2000, Biopolymers.

[9]  O. Chertov,et al.  Leukocyte granule proteins mobilize innate host defenses and adaptive immune responses , 2000, Immunological reviews.

[10]  C. Bevins,et al.  Antimicrobial Peptides as Mediators of Epithelial Host Defense , 1999, Pediatric Research.

[11]  D. Schwartz,et al.  Toll-like receptor 4 polymorphisms and atherogenesis. , 2002, The New England journal of medicine.

[12]  Tomas Ganz,et al.  Endogenous antimicrobial peptides and skin infections in atopic dermatitis. , 2002, The New England journal of medicine.