Epigenetic mechanisms of chronic pain

[1]  E. Navratilova,et al.  Reward and motivation in pain and pain relief , 2014, Nature Neuroscience.

[2]  Chih-Shung Wong,et al.  Baicalin ameliorates neuropathic pain by suppressing HDAC1 expression in the spinal cord of spinal nerve ligation rats. , 2014, Journal of the Formosan Medical Association = Taiwan yi zhi.

[3]  H. Okano,et al.  Astrocytic activation in the anterior cingulate cortex is critical for sleep disorder under neuropathic pain , 2014, Synapse.

[4]  F. Dekker,et al.  Small molecule inhibitors of histone acetyltransferases and deacetylases are potential drugs for inflammatory diseases. , 2014, Drug discovery today.

[5]  R. Peyron,et al.  Pain matrices and neuropathic pain matrices: A review , 2013, PAIN®.

[6]  Wei Zhou,et al.  Intrathecal miR-96 Inhibits Nav1.3 Expression and Alleviates Neuropathic Pain in Rat Following Chronic Construction Injury , 2013, Neurochemical Research.

[7]  J. Sweatt,et al.  The Emerging Field of Neuroepigenetics , 2013, Neuron.

[8]  F. Kronenberg,et al.  microRNAs in nociceptive circuits as predictors of future clinical applications , 2013, Front. Mol. Neurosci..

[9]  Scott J. Russo,et al.  The brain reward circuitry in mood disorders , 2013, Nature Reviews Neuroscience.

[10]  A. A. Romanovsky,et al.  An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathways , 2013, PAIN®.

[11]  F. Saitow,et al.  miR-7a alleviates the maintenance of neuropathic pain through regulation of neuronal excitability. , 2013, Brain : a journal of neurology.

[12]  Hidenori Suzuki,et al.  Nerve injury-induced upregulation of miR-21 in the primary sensory neurons contributes to neuropathic pain in rats. , 2013, Biochemical and biophysical research communications.

[13]  M. Bushnell,et al.  Cognitive and emotional control of pain and its disruption in chronic pain , 2013, Nature Reviews Neuroscience.

[14]  G. Shi,et al.  Increased miR‐195 aggravates neuropathic pain by inhibiting autophagy following peripheral nerve injury , 2013, Glia.

[15]  M. Krishna,et al.  Prevalence of Insomnia in Patients with Chronic Back Pain , 2013, Journal of orthopaedic surgery.

[16]  X. Jiang,et al.  Regulation of μ‐opioid type 1 receptors by microRNA134 in dorsal root ganglion neurons following peripheral inflammation , 2013, European journal of pain.

[17]  G. Geisslinger,et al.  Modulation of central nervous system–specific microRNA-124a alters the inflammatory response in the formalin test in mice , 2013, PAIN®.

[18]  H. Okano,et al.  Epigenetic transcriptional activation of monocyte chemotactic protein 3 contributes to long-lasting neuropathic pain. , 2013, Brain : a journal of neurology.

[19]  F. Nicoletti,et al.  L-acetylcarnitine causes rapid antidepressant effects through the epigenetic induction of mGlu2 receptors , 2013, Proceedings of the National Academy of Sciences.

[20]  M. Bushnell,et al.  Peripheral Nerve Injury Is Associated with Chronic, Reversible Changes in Global DNA Methylation in the Mouse Prefrontal Cortex , 2013, PloS one.

[21]  E. Nestler,et al.  Epigenetic mechanisms of depression and antidepressant action. , 2013, Annual review of pharmacology and toxicology.

[22]  M. Millecamps,et al.  Peripheral nerve injury is accompanied by chronic transcriptome-wide changes in the mouse prefrontal cortex , 2013, Molecular pain.

[23]  L. Simon RELIEVING PAIN IN AMERICA: A BLUEPRINT FOR TRANSFORMING PREVENTION, CARE, EDUCATION, AND RESEARCH , 2012 .

[24]  Thomas J. Schnitzer,et al.  Corticostriatal functional connectivity predicts transition to chronic back pain , 2012, Nature Neuroscience.

[25]  M. Barrot,et al.  Tests and models of nociception and pain in rodents , 2012, Neuroscience.

[26]  J. Byrne,et al.  Serotonin-Mediated Synapsin Expression Is Necessary for Long-Term Facilitation of the Aplysia Sensorimotor Synapse , 2011, The Journal of Neuroscience.

[27]  E. Nestler,et al.  Transcriptional and epigenetic mechanisms of addiction , 2011, Nature Reviews Neuroscience.

[28]  M. Narita,et al.  Change in MicroRNAs Associated with Neuronal Adaptive Responses in the Nucleus Accumbens under Neuropathic Pain , 2011, The Journal of Neuroscience.

[29]  B. Schmidt,et al.  Re-expression of the methylated EDNRB gene in oral squamous cell carcinoma attenuates cancer-induced pain , 2011, PAIN®.

[30]  O. Thoumine,et al.  Bidirectional integrative regulation of Cav1.2 calcium channel by microRNA miR‐103: role in pain , 2011, The EMBO journal.

[31]  Guohui Ding,et al.  Profile of MicroRNAs following Rat Sciatic Nerve Injury by Deep Sequencing: Implication for Mechanisms of Nerve Regeneration , 2011, PloS one.

[32]  W. Ong,et al.  MicroRNA changes in the mouse prefrontal cortex after inflammatory pain , 2011, European journal of pain.

[33]  Zhi Zhang,et al.  Epigenetic suppression of GAD65 expression mediates persistent pain , 2011, Nature Medicine.

[34]  Erika D. Nelson,et al.  Epigenetics in the mature mammalian brain: Effects on behavior and synaptic transmission , 2011, Neurobiology of Learning and Memory.

[35]  Akira Yamashita,et al.  Sleep disturbances in a neuropathic pain-like condition in the mouse are associated with altered GABAergic transmission in the cingulate cortex , 2011, PAIN.

[36]  I. Louro,et al.  Methylation analysis of cancer-related genes in non-neoplastic cells from patients with oral squamous cell carcinoma , 2011, Molecular Biology Reports.

[37]  Min Zhuo,et al.  Alleviating Neuropathic Pain Hypersensitivity by Inhibiting PKMζ in the Anterior Cingulate Cortex , 2010, Science.

[38]  G. Dussor,et al.  Central modulation of pain. , 2010, The Journal of clinical investigation.

[39]  Matthias Merkenschlager,et al.  Small RNAs Control Sodium Channel Expression, Nociceptor Excitability, and Pain Thresholds , 2010, The Journal of Neuroscience.

[40]  J. Morrison,et al.  Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens , 2010, Nature Neuroscience.

[41]  M. Baliki,et al.  Predicting Value of Pain and Analgesia: Nucleus Accumbens Response to Noxious Stimuli Changes in the Presence of Chronic Pain , 2010, Neuron.

[42]  Robert W Gereau,et al.  Transcriptional regulation of type-2 metabotropic glutamate receptors: an epigenetic path to novel treatments for chronic pain. , 2010, Trends in pharmacological sciences.

[43]  Lin Ma,et al.  Epigenetic Gene Silencing Underlies C-Fiber Dysfunctions in Neuropathic Pain , 2010, The Journal of Neuroscience.

[44]  R. Dubner,et al.  Inhibition of class II histone deacetylases in the spinal cord attenuates inflammatory hyperalgesia , 2010, Molecular pain.

[45]  David Julius,et al.  Cellular and Molecular Mechanisms of Pain , 2009, Cell.

[46]  F. Nicoletti,et al.  Epigenetic Modulation of mGlu2 Receptors by Histone Deacetylase Inhibitors in the Treatment of Inflammatory Pain , 2009, Molecular Pharmacology.

[47]  S. Derbyshire,et al.  Fibromyalgia pain and its modulation by hypnotic and non‐hypnotic suggestion: An fMRI analysis , 2009, European journal of pain.

[48]  J. Mogil Animal models of pain: progress and challenges , 2009, Nature Reviews Neuroscience.

[49]  D. Bartel MicroRNAs: Target Recognition and Regulatory Functions , 2009, Cell.

[50]  L. Crepaldi,et al.  Chromatin learns to behave , 2009, Epigenetics.

[51]  M. Zhuo,et al.  Enhanced quantal release of excitatory transmitter in anterior cingulate cortex of adult mice with chronic pain , 2009, Molecular pain.

[52]  Kelly E. Flock,et al.  Effects of trichostatin A on neuronal mu-opioid receptor gene expression , 2008, Brain Research.

[53]  E. Nestler,et al.  Epigenetics in the Nervous System , 2008, The Journal of Neuroscience.

[54]  Jingwei Wu,et al.  Association of Depression and Anxiety Alone and in Combination With Chronic Musculoskeletal Pain in Primary Care Patients , 2008, Psychosomatic medicine.

[55]  D. Ziegler Painful diabetic neuropathy: treatment and future aspects , 2008, Diabetes/metabolism research and reviews.

[56]  B. Schmidt,et al.  Effect of peripheral endothelin‐1 concentration on carcinoma‐induced pain in mice , 2008, European journal of pain.

[57]  Min Zhuo,et al.  Cortical excitation and chronic pain , 2008, Trends in Neurosciences.

[58]  G. Gebhart,et al.  Neurotensin-produced antinociception in the rostral ventromedial medulla is partially mediated by spinal cord norepinephrine , 2008, PAIN.

[59]  S. Hunt,et al.  Descending serotonergic controls regulate inflammation-induced mechanical sensitivity and methyl-CpG-binding protein 2 phosphorylation in the rat superficial dorsal horn , 2008 .

[60]  Guanghua Xiao,et al.  Histone Deacetylase 5 Epigenetically Controls Behavioral Adaptations to Chronic Emotional Stimuli , 2007, Neuron.

[61]  C. Woolf,et al.  The neuropathic pain triad: neurons, immune cells and glia , 2007, Nature Neuroscience.

[62]  Irene Tracey,et al.  The Cerebral Signature for Pain Perception and Its Modulation , 2007, Neuron.

[63]  S. Hunt,et al.  A Role for Transcriptional Repressor Methyl-CpG-Binding Protein 2 and Plasticity-Related Gene Serum- and Glucocorticoid-Inducible Kinase 1 in the Induction of Inflammatory Pain States , 2007, The Journal of Neuroscience.

[64]  S. Berger The complex language of chromatin regulation during transcription , 2007, Nature.

[65]  T. Kouzarides Chromatin Modifications and Their Function , 2007, Cell.

[66]  D. Dessem,et al.  Downregulation of selective microRNAs in trigeminal ganglion neurons following inflammatory muscle pain , 2007, Molecular pain.

[67]  Hiroshi Ikeda,et al.  Synaptic Amplifier of Inflammatory Pain in the Spinal Dorsal Horn , 2006, Science.

[68]  M. Bushnell,et al.  Thermal and Tactile Sensory Deficits and Allodynia in a Nerve-Injured Patient: A Multimodal Psychophysical and Functional Magnetic Resonance Imaging Study , 2006, The Clinical journal of pain.

[69]  Robert W Gereau,et al.  Transcriptional regulation of metabotropic glutamate receptor 2/3 expression by the NF-κB pathway in primary dorsal root ganglia neurons: a possible mechanism for the analgesic effect of L-acetylcarnitine , 2006, Molecular pain.

[70]  J. Chelly,et al.  Molecular genetics of Rett syndrome: when DNA methylation goes unrecognized , 2006, Nature Reviews Genetics.

[71]  M. Zhuo,et al.  A behavioral model of neuropathic pain induced by ligation of the common peroneal nerve in mice. , 2005, The journal of pain : official journal of the American Pain Society.

[72]  Y. Nagumo,et al.  Protease-Activated Receptor-1 and Platelet-Derived Growth Factor in Spinal Cord Neurons Are Implicated in Neuropathic Pain after Nerve Injury , 2005, The Journal of Neuroscience.

[73]  M. Devor,et al.  Efficacy of antiepileptic isomers of valproic acid and valpromide in a rat model of neuropathic pain , 2005, British journal of pharmacology.

[74]  R. Treede,et al.  Human brain mechanisms of pain perception and regulation in health and disease , 2005, European journal of pain.

[75]  T. Spector,et al.  Epigenetic differences arise during the lifetime of monozygotic twins. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[76]  M. Calvani,et al.  Acetyl-L-carnitine improves pain, nerve regeneration, and vibratory perception in patients with chronic diabetic neuropathy: an analysis of two randomized placebo-controlled trials. , 2005, Diabetes care.

[77]  P. Mantyh,et al.  Endothelin and the tumorigenic component of bone cancer pain , 2004, Neuroscience.

[78]  H. Loh,et al.  Neuron-restrictive Silencer Factor (NRSF) Functions as a Repressor in Neuronal Cells to Regulate the μ Opioid Receptor Gene* , 2004, Journal of Biological Chemistry.

[79]  V. Neugebauer,et al.  The Amygdala and Persistent Pain , 2004, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.

[80]  Ivan V. Gregoretti,et al.  Molecular evolution of the histone deacetylase family: functional implications of phylogenetic analysis. , 2004, Journal of molecular biology.

[81]  C. Woolf,et al.  Central sensitization and LTP: do pain and memory share similar mechanisms? , 2003, Trends in Neurosciences.

[82]  A. Craig,et al.  Pain mechanisms: labeled lines versus convergence in central processing. , 2003, Annual review of neuroscience.

[83]  Eric C. Griffith,et al.  Derepression of BDNF Transcription Involves Calcium-Dependent Phosphorylation of MeCP2 , 2003, Science.

[84]  Tony Kouzarides,et al.  The Methyl-CpG-binding Protein MeCP2 Links DNA Methylation to Histone Methylation* , 2003, The Journal of Biological Chemistry.

[85]  Arnold H. Buss Pathways , 2002, Journal of personality assessment.

[86]  Dimitris Thanos,et al.  Integration of Long-Term-Memory-Related Synaptic Plasticity Involves Bidirectional Regulation of Gene Expression and Chromatin Structure , 2002, Cell.

[87]  T. Vanderah,et al.  Time-Dependent Descending Facilitation from the Rostral Ventromedial Medulla Maintains, But Does Not Initiate, Neuropathic Pain , 2002, The Journal of Neuroscience.

[88]  G. Gebhart,et al.  Chronic pain and medullary descending facilitation , 2002, Trends in Neurosciences.

[89]  A. Caricasole,et al.  L-Acetylcarnitine induces analgesia by selectively up-regulating mGlu2 metabotropic glutamate receptors. , 2002, Molecular pharmacology.

[90]  E. Kandel The Molecular Biology of Memory Storage: A Dialogue Between Genes and Synapses , 2001, Science.

[91]  M. Bushnell,et al.  Representation of Acute and Persistent Pain in the Human CNS: Potential Implications for Chemical Intolerance , 2001, Annals of the New York Academy of Sciences.

[92]  I. Adcock,et al.  Glucocorticoid Receptor Recruitment of Histone Deacetylase 2 Inhibits Interleukin-1β-Induced Histone H4 Acetylation on Lysines 8 and 12 , 2000, Molecular and Cellular Biology.

[93]  D. Price Psychological and neural mechanisms of the affective dimension of pain. , 2000, Science.

[94]  C. Woolf,et al.  Neuronal plasticity: increasing the gain in pain. , 2000, Science.

[95]  R. LaMotte,et al.  Plasticity of sodium channel expression in DRG neurons in the chronic constriction injury model of neuropathic pain , 1999, PAIN®.

[96]  M. Zhuo,et al.  Loss of Synaptic Depression in Mammalian Anterior Cingulate Cortex after Amputation , 1999, The Journal of Neuroscience.

[97]  C. Woolf,et al.  Neuropathic pain: aetiology, symptoms, mechanisms, and management , 1999, The Lancet.

[98]  J. Dostrovsky,et al.  Pain-related neurons in the human cingulate cortex , 1999, Nature Neuroscience.

[99]  J. Sandkühler,et al.  Induction of long‐term potentiation at spinal synapses by noxious stimulation or nerve injury , 1998, The European journal of neuroscience.

[100]  M. Zhuo,et al.  Biphasic modulation of spinal nociceptive transmission from the medullary raphe nuclei in the rat. , 1997, Journal of neurophysiology.

[101]  G. Collingridge,et al.  The synaptic activation of kainate receptors , 1997, Nature.

[102]  R. Ji,et al.  Phosphorylation of Transcription Factor CREB in Rat Spinal Cord after Formalin-Induced Hyperalgesia: Relationship toc-fos Induction , 1997, The Journal of Neuroscience.

[103]  E. Scarpini,et al.  Effect of acetyl-L-carnitine in the treatment of painful peripheral neuropathies in HIV+ patients. , 1997, Journal of the peripheral nervous system : JPNS.

[104]  J. Stamford Descending control of pain. , 1995, British journal of anaesthesia.

[105]  T. Yaksh,et al.  Quantitative assessment of tactile allodynia in the rat paw , 1994, Journal of Neuroscience Methods.

[106]  S. Hyman,et al.  The Molecular Foundations Of Psychiatry , 1993 .

[107]  Alan C. Evans,et al.  Multiple representations of pain in human cerebral cortex. , 1991, Science.

[108]  R. Dubner,et al.  A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia , 1987, Pain.

[109]  H. Fields,et al.  Evidence that an excitatory connection between the periaqueductal gray and nucleus raphe magnus mediates stimulation produced analgesia , 1979, Brain Research.