Irreversible pan-ErbB tyrosine kinase inhibitor CI-1033 induces caspase-independent apoptosis in colorectal cancer DiFi cell line

[1]  R. Coffey,et al.  Characterization of the DiFi Rectal carcinoma cell line derived from a familial adenomatous polyposis patient , 1993, In Vitro Cellular & Developmental Biology - Animal.

[2]  Z. Hua Cetuximab Monotherapy and Cetuximab plus Irinotecan in Irinotecan-Refractory Metastatic Colorectal Cancer , 2006 .

[3]  David S. Park,et al.  Apoptosis-Inducing Factor Is a Key Factor in Neuronal Cell Death Propagated by BAX-Dependent and BAX-Independent Mechanisms , 2005, The Journal of Neuroscience.

[4]  B. Sarg,et al.  Different proteome pattern of epidermal growth factor receptor-positive colorectal cancer cell lines that are responsive and nonresponsive to C225 antibody treatment. , 2004, Molecular cancer therapeutics.

[5]  A. Tolcher,et al.  Administration of CI-1033, an Irreversible Pan-erbB Tyrosine Kinase Inhibitor, Is Feasible on a 7-Day On, 7-Day Off Schedule , 2004, Clinical Cancer Research.

[6]  G. Sheu,et al.  Molecular mechanisms of ZD1839-induced G1-cell cycle arrest and apoptosis in human lung adenocarcinoma A549 cells. , 2004, Biochemical pharmacology.

[7]  M. Michalak,et al.  Calreticulin, Ca2+, and calcineurin - signaling from the endoplasmic reticulum. , 2004, Molecules and cells.

[8]  K. Chayama,et al.  Induction of apoptosis by ionizing radiation and CI-1033 in HuCCT-1 cells. , 2004, Biochemical and biophysical research communications.

[9]  T. Cotter,et al.  Control of mitochondrial integrity by Bcl-2 family members and caspase-independent cell death. , 2004, Biochimica et biophysica acta.

[10]  S. Sheng,et al.  Bax Mediates the Apoptosis-Sensitizing Effect of Maspin , 2004, Cancer Research.

[11]  M. Campiglio,et al.  Inhibition of proliferation and induction of apoptosis in breast cancer cells by the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor ZD1839 (‘Iressa’) is independent of EGFR expression level , 2004, Journal of cellular physiology.

[12]  G. Konjević,et al.  TNF-α induces changes in LDH isotype profile following triggering of apoptosis in PBL of non-Hodgkin’s lymphomas , 2004, Annals of Hematology.

[13]  Y. Courtois,et al.  L-DNase II associated with active process during ethanol induced cell death in ARPE-19. , 2004, Molecular vision.

[14]  A. Chinnaiyan,et al.  Radiosensitization by Pan ErbB Inhibitor CI-1033 in Vitro and in Vivo , 2004, Clinical Cancer Research.

[15]  G. Konjević,et al.  TNF-alpha induces changes in LDH isotype profile following triggering of apoptosis in PBL of non-Hodgkin's lymphomas. , 2004, Annals of hematology.

[16]  B. Sarg,et al.  Calgranulins in cystic fluid and serum from patients with ovarian carcinomas. , 2003, Cancer research.

[17]  D. W. Fry,et al.  CI-1033, an irreversible pan-erbB receptor inhibitor and its potential application for the treatment of breast cancer. , 2003, Seminars in oncology.

[18]  F. Harper,et al.  Cathepsin D Triggers Bax Activation, Resulting in Selective Apoptosis-inducing Factor (AIF) Relocation in T Lymphocytes Entering the Early Commitment Phase to Apoptosis* , 2003, Journal of Biological Chemistry.

[19]  P. Bonomi Clinical studies with non-iressa EGFR tyrosine kinase inhibitors. , 2003, Lung cancer.

[20]  J. Tschopp,et al.  Caspase-independent cell death in T lymphocytes , 2003, Nature Immunology.

[21]  S. Sheng,et al.  Maspin sensitizes breast carcinoma cells to induced apoptosis , 2002, Oncogene.

[22]  G. Kroemer,et al.  Apoptosis-inducing factor (AIF): a novel caspase-independent death effector released from mitochondria. , 2002, Biochimie.

[23]  Mingde Zhao,et al.  Sphingosine-induced apoptosis is dependent on lysosomal proteases. , 2001, The Biochemical journal.

[24]  D. W. Fry,et al.  CI-1033, a pan-erbB tyrosine kinase inhibitor. , 2001, Seminars in oncology.

[25]  D. W. Fry,et al.  Akt, MAPK (Erk1/2), and p38 Act in Concert to Promote Apoptosis in Response to ErbB Receptor Family Inhibition* , 2001, The Journal of Biological Chemistry.

[26]  R. Chandraratna,et al.  Evidence of a lysosomal pathway for apoptosis induced by the synthetic retinoid CD437 in human leukemia HL-60 cells , 2001, Cell Death and Differentiation.

[27]  M. Leist,et al.  Triggering of apoptosis by cathepsins , 2001, Cell Death and Differentiation.

[28]  T. Dörk,et al.  Nuclear factor TDP‐43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping , 2001, The EMBO journal.

[29]  G. Kroemer,et al.  Dominant cell death induction by extramitochondrially targeted apoptosis‐inducing factor , 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[30]  John Mendelsohn,et al.  The EGF receptor family as targets for cancer therapy , 2000, Oncogene.

[31]  E. Musgrove,et al.  The nuclear chloride ion channel NCC27 is involved in regulation of the cell cycle , 2000, The Journal of physiology.

[32]  S. Ethier,et al.  Radiosensitization of human breast cancer cells by a novel ErbB family receptor tyrosine kinase inhibitor. , 2000, International journal of radiation oncology, biology, physics.

[33]  P. Srivastava,et al.  Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kappa B pathway. , 2000, International immunology.

[34]  Michal Opas,et al.  Changes in Endoplasmic Reticulum Luminal Environment Affect Cell Sensitivity to Apoptosis , 2000, The Journal of cell biology.

[35]  S. Valenzuela,et al.  Functional characterization of the NCC27 nuclear protein in stable transfected CHO‐K1 cells , 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[36]  J. Mendelsohn,et al.  Induction of apoptosis and activation of the caspase cascade by anti-EGF receptor monoclonal antibodies in DiFi human colon cancer cells do not involve the c- jun N-terminal kinase activity , 2000, British Journal of Cancer.

[37]  M. Kasahara,et al.  Growth Retardation in Mice Lacking the Proteasome Activator PA28γ* , 1999, The Journal of Biological Chemistry.

[38]  Y. Lee,et al.  Glibenclamide induces apoptosis through inhibition of cystic fibrosis transmembrane conductance regulator (CFTR) Cl(-) channels and intracellular Ca(2+) release in HepG2 human hepatoblastoma cells. , 1999, Biochemical and biophysical research communications.

[39]  C. Slaughter,et al.  The Proteasome, a Novel Protease Regulated by Multiple Mechanisms* , 1999, The Journal of Biological Chemistry.

[40]  Y. Courtois,et al.  Differential involvement of DNases in HeLa cell apoptosis induced by etoposide and long term-culture , 1999, Cell Death and Differentiation.

[41]  D. Huang,et al.  Regulation of LDH-A gene expression by transcriptional and posttranscriptional signal transduction mechanisms. , 1998, The Journal of experimental zoology.

[42]  M. Mandal,et al.  Nuclear targeting of Bax during apoptosis in human colorectal cancer cells , 1998, Oncogene.

[43]  P. Perani,et al.  L-DNase II, a Molecule That Links Proteases and Endonucleases in Apoptosis, Derives from the Ubiquitous Serpin Leukocyte Elastase Inhibitor , 1998, Molecular and Cellular Biology.

[44]  S. de Jong,et al.  Expression of proteins correlated with the unique cisplatin-sensitivity of testicular cancer. , 1997, Anticancer research.

[45]  Y. Courtois,et al.  Involvement of DNase II in Nuclear Degeneration during Lens Cell Differentiation (*) , 1995, The Journal of Biological Chemistry.

[46]  D Harrich,et al.  Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs , 1995, Journal of virology.

[47]  N. Rosen,et al.  Apoptosis induced by an anti-epidermal growth factor receptor monoclonal antibody in a human colorectal carcinoma cell line and its delay by insulin. , 1995, The Journal of clinical investigation.

[48]  M. Hendrix,et al.  Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells. , 1994, Science.

[49]  J. Wilson,et al.  Expression of an abundant alternatively spliced form of the cystic fibrosis transmembrane conductance regulator (CFTR) gene is not associated with a cAMP-activated chloride conductance. , 1993, Human molecular genetics.

[50]  C. Creutz The annexins and exocytosis. , 1992, Science.

[51]  D. Salomon,et al.  Differential expression of epidermal growth factor-related proteins in human colorectal tumors. , 1991, Proceedings of the National Academy of Sciences of the United States of America.