Mice lacking smooth muscle calponin display increased bone formation that is associated with enhancement of bone morphogenetic protein responses

Calponin is a calmodulin‐and actin‐binding protein expressed in smooth muscle. It promotes actin polymerization and inhibits actin‐activated myosin ATPase activity. Despite the molecular and functional characterization of calponin in vitro, the physiological role of calponin in vivo has not been clarified.

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