Presence of apolipoprotein E immunoreactivity in degenerating neurones of mice is dependent on the severity of kainic acid-induced lesion

[1]  S. Strickland,et al.  Neuronal Death and Blood–Brain Barrier Breakdown after Excitotoxic Injury Are Independent Processes , 1999, The Journal of Neuroscience.

[2]  G. Rondouin,et al.  Hippocampal alterations of apolipoprotein E and D mRNA levels in vivo and in vitro following kainate excitotoxicity , 1999, Epilepsy Research.

[3]  R. Pearlstein,et al.  Apolipoprotein E deficiency worsens outcome from global cerebral ischemia in the mouse. , 1999, Stroke.

[4]  R. Demattos,et al.  A Test of the Cytosolic Apolipoprotein E Hypothesis Fails to Detect the Escape of Apolipoprotein E from the Endocytic Pathway into the Cytosol and Shows that Direct Expression of Apolipoprotein E in the Cytosol is Cytotoxic , 1999, The Journal of Neuroscience.

[5]  D. Graham,et al.  Influence of apolipoprotein E genotype on neuronal damage and apoE immunoreactivity in human hippocampus following global ischemia. , 1999, Journal of neuropathology and experimental neurology.

[6]  J. Gilbert,et al.  Specific regional transcription of apolipoprotein E in human brain neurons. , 1999, The American journal of pathology.

[7]  P. Froom,et al.  Apolipoprotein E-ε4 genotype predicts a poor outcome in survivors of traumatic brain injury , 1999, Neurology.

[8]  B. Hyman,et al.  Dissociation of apolipoprotein and apolipoprotein receptor response to lesion in the rat brain: An in situ hybridization study , 1998, Neuroscience.

[9]  A. Fagan,et al.  Evidence for Normal Aging of the Septo-Hippocampal Cholinergic System in apoE (−/−) Mice but Impaired Clearance of Axonal Degeneration Products Following Injury , 1998, Experimental Neurology.

[10]  A. Roses,et al.  Apolipoprotein E and the CNS Response to Injury , 1998, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[11]  J. Victoroff,et al.  Increased Apolipoprotein E mRNA in the Hippocampus in Alzheimer Disease and in Rats after Entorhinal Cortex Lesioning , 1998, Experimental Neurology.

[12]  T. McNeill,et al.  Differential Regulation of Astrocytic mRNAs in the Rat Striatum after Lesions of the Cortex or Substantia Nigra , 1998, Experimental Neurology.

[13]  A. Roses Apolipoprotein E, a Gene with Complex Biological Interactions in the Aging Brain , 1997, Neurobiology of Disease.

[14]  T. Wisniewski,et al.  Biology of Aβ Amyloid in Alzheimer's Disease , 1997, Neurobiology of Disease.

[15]  R. T. Carroll,et al.  Cerebral lipid deposition in aged apolipoprotein-E-deficient mice. , 1997, The American journal of pathology.

[16]  G. Murray,et al.  Association of apolipoprotein E polymorphism with outcome after head injury , 1997, The Lancet.

[17]  D. Michaelson,et al.  Motor and cognitive deficits in apolipoprotein E-deficient mice after closed head injury , 1997, Neuroscience.

[18]  J. Nicoll,et al.  Marked alterations in the cellular localisation and levels of apolipoprotein E following acute subdural haematoma in rat , 1997, Brain Research.

[19]  C. Kawas,et al.  Neuronal cell death in Alzheimer's disease correlates with apoE uptake and intracellular Abeta stabilization. , 1997, The Journal of clinical investigation.

[20]  A. Roses,et al.  Apolipoprotein E-Deficient Mice Have Increased Susceptibility To Focal Cerebral Ischemia , 1997, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[21]  W. Ong,et al.  Differential expression of apolipoprotein D and apolipoprotein E in the kainic acid-lesioned rat hippocampus , 1997, Neuroscience.

[22]  M. Gearing,et al.  Astrocyte‐Apolipoprotein E Associations in Senile Plaques in Alzheimer Disease and Vascular Lesions: A Regional Immunohistochemical Study , 1997, Journal of neuropathology and experimental neurology.

[23]  L. Havekes,et al.  Severe learning deficits in apolipoprotein E-knockout mice in a water maze task , 1997, Brain Research.

[24]  A. Hofman,et al.  Apolipoprotein E epsilon4 and the risk of dementia with stroke. A population-based investigation. , 1997, JAMA.

[25]  T. Morgan,et al.  Astrocytes and Microglia Respond to Estrogen with Increased apoE mRNAin Vivoandin Vitro , 1997, Experimental Neurology.

[26]  E. Masliah,et al.  ALTERATIONS IN APOLIPOPROTEIN E EXPRESSION DURING AGING AND NEURODEGENERATION , 1996, Progress in Neurobiology.

[27]  Jonathan D. Smith,et al.  Apolipoprotein E allele–specific antioxidant activity and effects on cytotoxicity by oxidative insults and β–amyloid peptides , 1996, Nature Genetics.

[28]  K. Horsburgh,et al.  Selective alterations in the cellular distribution of apolipoprotein E immunoreactivity following transient cerebral ischaemia in the rat , 1996, Neuropathology and applied neurobiology.

[29]  Bradley T. Hyman,et al.  Apolipoprotein E ε4 Is Associated With the Presence and Earlier Onset of Hemorrhage in Cerebral Amyloid Angiopathy , 1996 .

[30]  Grootendorst,et al.  Dexamethasone Does Not Prevent Seven-Day ADX-Induced Apoptosis in the Dentate Gyrus of the Rat Hippocampus. , 1996, Stress.

[31]  G. Getz,et al.  Neurons of the Human Frontal Cortex Display Apolipoprotein E Immunoreactivity: Implications for Alzheimer's Disease , 1996, Journal of neuropathology and experimental neurology.

[32]  L. Donehower,et al.  Loss of the p53 tumor suppressor gene protects neurons from kainate- induced cell death , 1996, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[33]  R. Mahley,et al.  Apolipoprotein E. Structure, Function, and Possible Roles in Alzheimer's Disease a , 1996, Annals of the New York Academy of Sciences.

[34]  J. Gilbert,et al.  Morphological, Biochemical, and Genetic Support for an Apolipoprotein E Effect on Microtubular Metabolism a , 1996, Annals of the New York Academy of Sciences.

[35]  A. Roses,et al.  Neurodegeneration in the Central Nervous System of apoE-Deficient Mice , 1995, Experimental Neurology.

[36]  R. Mahley,et al.  Stable Expression and Secretion of Apolipoproteins E3 and E4 in Mouse Neuroblastoma Cells Produces Differential Effects on Neurite Outgrowth (*) , 1995, The Journal of Biological Chemistry.

[37]  D. Holtzman,et al.  Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[38]  E. Hall,et al.  Increased Amyloid Protein Precursor and Apolipoprotein E Immunoreactivity in the Selectively Vulnerable Hippocampus Following Transient Forebrain Ischemia in Gerbils , 1995, Experimental Neurology.

[39]  K. Wisniewski,et al.  Deposition of apolipoproteins E and J in senile plaques is topographically determined in both Alzheimer's disease and Down's syndrome brain , 1995, Brain Research.

[40]  H. Wiśniewski,et al.  Complete cerebral ischemia with short-term survival in rat induced by cardiac arrest. II. Extracellular and intracellular accumulation of apolipoproteins E and J in the brain , 1995, Brain Research.

[41]  J. Poirier Apolipoprotein E in animal models of CNS injury and in alzheimer's disease , 1994, Trends in Neurosciences.

[42]  J. de Olmos,et al.  Use of an amino-cupric-silver technique for the detection of early and semiacute neuronal degeneration caused by neurotoxicants, hypoxia, and physical trauma. , 1994, Neurotoxicology and teratology.

[43]  B. Wieringa,et al.  Diet-induced hypercholesterolemia and atherosclerosis in heterozygous apolipoprotein E-deficient mice. , 1994, Atherosclerosis.

[44]  A. Roses,et al.  Apolipoprotein E Is Localized to the Cytoplasm of Human Cortical Neurons: A Light and Electron Microscopic Study , 1994, Journal of neuropathology and experimental neurology.

[45]  M. Pericak-Vance,et al.  Apolipoprotein E Is Present in Hippocampal Neurons without Neurofibrillary Tangles in Alzheimer's Disease and in Age-Matched Controls , 1994, Experimental Neurology.

[46]  V. Perry,et al.  Mitosis and apoptosis of microgliain vivo induced by an anti-CR3 antibody which crosses the blood-brain barrier , 1993, Neuroscience.

[47]  M. Pericak-Vance,et al.  Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[48]  B. Hyman,et al.  Neuroanatomical connections and specific regional vulnerability in Alzheimer's disease , 1993, Neurobiology of Aging.

[49]  K. Sako,et al.  Experimental complex partial seizures induced by a microinjection of kainic acid into limbic structures , 1992, Progress in Neurobiology.

[50]  J. Korf,et al.  Time course and distribution of neuronal degeneration in the dentate gyrus of rat after adrenalectomy: A silver impregnation study , 1992, Hippocampus.

[51]  V. Perry,et al.  The kinetics and morphological characteristics of the macrophage-microglial response to kainic acid-induced neuronal degeneration , 1991, Neuroscience.

[52]  A. Haase,et al.  Neuropathological changes in scrapie and Alzheimer's disease are associated with increased expression of apolipoprotein E and cathepsin D in astrocytes , 1991, Journal of virology.

[53]  C. Finch,et al.  Astrocytic apolipoprotein E mRNA and GFAP mRNA in hippocampus after entorhinal cortex lesioning. , 1991, Brain research. Molecular brain research.

[54]  L. Notterpek,et al.  Accumulation of apolipoproteins in the regenerating and remyelinating mammalian peripheral nerve. Identification of apolipoprotein D, apolipoprotein A-IV, apolipoprotein E, and apolipoprotein A-I. , 1990, The Journal of biological chemistry.

[55]  H. Rosen,et al.  The role of the type 3 complement receptor in the induced recruitment of myelomonocytic cells to inflammatory sites in the mouse. , 1990, American journal of respiratory cell and molecular biology.

[56]  H. Shimano,et al.  Plasma apolipoproteins in patients with multi-infarct dementia. , 1989, Atherosclerosis.

[57]  E. Shooter,et al.  A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve. , 1989, The Journal of clinical investigation.

[58]  L. Swanson,et al.  Localization of mRNA for low density lipoprotein receptor and a cholesterol synthetic enzyme in rabbit nervous system by in situ hybridization. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[59]  R. Mahley,et al.  Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. , 1988, Science.

[60]  G. Stoll,et al.  Macrophages in the peripheral nervous system and astroglia in the central nervous system of rat commonly express apolipoprotein E during development but differ in their response to injury , 1986, Neuroscience Letters.

[61]  E. Shooter,et al.  Expression of apolipoprotein E during nerve degeneration and regeneration. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[62]  J. Freeman,et al.  Nerve injury stimulates the secretion of apolipoprotein E by nonneuronal cells. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[63]  J. Taylor,et al.  Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system. , 1985, The Journal of clinical investigation.

[64]  O. Hornykiewicz,et al.  Kainic acid-induced seizures: Dose-relationship of behavioural neurochemical and histopathological changes , 1985, Brain Research.

[65]  E. Shooter,et al.  A specific 37,000-dalton protein that accumulates in regenerating but not in nonregenerating mammalian nerves. , 1985, Science.

[66]  S. Kish,et al.  Kainic acid induced seizures: Neurochemical and histopathological changes , 1983, Neuroscience.

[67]  A. Roses,et al.  Apolipoprotein E and Alzheimer's disease. , 1996, Annual review of neuroscience.

[68]  O. Steward,et al.  Genetic determinants of susceptibility to excitotoxic cell death: implications for gene targeting approaches. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[69]  L. Heimer,et al.  Silver staining as a tool for neurotoxic assessment. , 1993, NIDA research monograph.

[70]  J. Nadler,et al.  [25] Use of excitatory amino acids to make axon-sparing lesions of hypothalamus , 1983 .