Activity of crustacean myotropic neuropeptides on the oviduct and hindgut of the crayfish Astacus leptodactylus

Summary In crustaceans, a large number of peptides have been identified because of their effect on visceral muscles. Predominantly the heart and the hindgut have been used to purify myotropic peptides from crustaceans. Lately, a number of myotropins were purified from the central nervous system of crustaceans through their ability to induce Leucophaea maderae hindgut contraction. Pev-tachykinin, Pev-SK 2, Pev-kinins 1–6 and Pev-PK 1 and 2 were tested on their ability to affect the contractility of the crayfish (Astacus leptodactylus) oviduct and hindgut. We have demonstrated for the first time that the muscular sheath surrounding the crayfish oviduct is a possible target for myotropic neuropeptides. The crustacean myokinins (Pev-kinins 1–6) were able to increase the basal tonus of the crustacean oviduct. The other tested myotropins were inactive in this bioassay. Pev-kinins proved to be potent stimulators of crayfish hindgut contraction, this in contrast to Pev-tachykinin and Pev-SK 2.

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