Rutin ameliorates inflammatory pain by inhibiting P2X7 receptor in mast cells

[1]  Wen-jun Zhang,et al.  P2X7 receptor in inflammation and pain , 2022, Brain Research Bulletin.

[2]  Hye-Ryung Park,et al.  A Comparative Study of Rutin and Rutin Glycoside: Antioxidant Activity, Anti-Inflammatory Effect, Effect on Platelet Aggregation and Blood Coagulation , 2021, Antioxidants.

[3]  Linfeng Zou,et al.  Rutin inhibited the advanced glycation end products-stimulated inflammatory response and extra-cellular matrix degeneration via targeting TRAF-6 and BCL-2 proteins in mouse model of osteoarthritis , 2021, Aging.

[4]  W. Fan,et al.  Involvement of Mast Cells in the Pathophysiology of Pain , 2021, Frontiers in Cellular Neuroscience.

[5]  L. Nahar,et al.  Anti-MRSA Constituents from Ruta chalepensis (Rutaceae) Grown in Iraq, and In Silico Studies on Two of Most Active Compounds, Chalepensin and 6-Hydroxy-rutin 3′,7-Dimethyl ether , 2021, Molecules.

[6]  S. Oran,et al.  Anti-nociceptive effect of Arbutus andrachne L. methanolic leaf extract mediated by CB1, TRPV1 and PPARs in mouse pain models , 2020, Inflammopharmacology.

[7]  Adedoyin O Adefisan,et al.  Rutin ameliorates copper sulfate‐induced brain damage via antioxidative and anti‐inflammatory activities in rats , 2020, Journal of biochemical and molecular toxicology.

[8]  D. C. Malvar,et al.  Oral treatments with a flavonoid-enriched fraction from Cecropia hololeuca and with rutin reduce articular pain and inflammation in murine zymosan-induced arthritis. , 2020, Journal of ethnopharmacology.

[9]  T. Theoharides,et al.  Mast Cells, Neuroinflammation and Pain in Fibromyalgia Syndrome , 2019, Front. Cell. Neurosci..

[10]  G. Traina Mast Cells in Gut and Brain and Their Potential Role as an Emerging Therapeutic Target for Neural Diseases , 2019, Front. Cell. Neurosci..

[11]  Chengbo Yang,et al.  Rutin attenuates inflammatory responses induced by lipopolysaccharide in an in vitro mouse muscle cell (C2C12) model. , 2019, Poultry science.

[12]  S. M. Borghi,et al.  The granulopoietic cytokine granulocyte colony-stimulating factor (G-CSF) induces pain: analgesia by rutin , 2019, Inflammopharmacology.

[13]  Xinzhong Dong,et al.  A Mast-Cell-Specific Receptor Mediates Neurogenic Inflammation and Pain , 2019, Neuron.

[14]  N. K. Simas,et al.  Phenolic compounds from Tocoyena bullata mart (Rubiaceae) with inhibitory activity in mast cells degranulation , 2019, Natural product research.

[15]  Na‐Ra Han,et al.  The new therapeutic herbal drug HM0601 and its bioactive compound rutin exert potent antiproliferative activities in mast cells , 2018, Fundamental & clinical pharmacology.

[16]  K. Gupta,et al.  Mast cell‐neural interactions contribute to pain and itch , 2018, Immunological reviews.

[17]  E. Fikry,et al.  Rutin and meloxicam attenuate paw inflammation in mice: Affecting sorbitol dehydrogenase activity , 2018, Journal of biochemical and molecular toxicology.

[18]  S. Habtemariam,et al.  Natural Therapies of the Inflammatory Bowel Disease: The Case of Rutin and its Aglycone, Quercetin. , 2018, Mini reviews in medicinal chemistry.

[19]  O. Aragon-Martinez,et al.  Synergism between Naproxen and Rutin in a Mouse Model of Visceral Pain , 2017, Drug development research.

[20]  R. Schmid,et al.  Unique residues in the ATP gated human P2X7 receptor define a novel allosteric binding pocket for the selective antagonist AZ10606120 , 2017, Scientific Reports.

[21]  A. Ganeshpurkar,et al.  The Pharmacological Potential of Rutin , 2016, Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society.

[22]  Xinzhong Dong,et al.  Identification of a mast cell specific receptor crucial for pseudo-allergic drug reactions , 2014, Nature.

[23]  S. Ku,et al.  Anti-inflammatory effects of rutin on HMGB1-induced inflammatory responses in vitro and in vivo , 2014, Inflammation Research.

[24]  F. Huygen,et al.  Mast Cells: A New Target in the Treatment of Complex Regional Pain Syndrome? , 2013, Pain practice : the official journal of World Institute of Pain.

[25]  Sang-Hyun Kim,et al.  Rutin suppresses atopic dermatitis and allergic contact dermatitis , 2013, Experimental biology and medicine.

[26]  G. Núñez,et al.  TLR Agonists Stimulate Nlrp3-Dependent IL-1β Production Independently of the Purinergic P2X7 Receptor in Dendritic Cells and In Vivo , 2013, The Journal of Immunology.

[27]  H. Iba,et al.  Extracellular ATP mediates mast cell-dependent intestinal inflammation through P2X7 purinoceptors , 2012, Nature Communications.

[28]  C. Parada,et al.  Peripheral mechanisms underlying the essential role of P2X7 receptors in the development of inflammatory hyperalgesia. , 2010, European journal of pharmacology.

[29]  K. Ren,et al.  Role of interleukin-1β during pain and inflammation , 2009, Brain Research Reviews.

[30]  Yongmoon Han Rutin has therapeutic effect on septic arthritis caused by Candida albicans. , 2009, International immunopharmacology.

[31]  Maan-Gee Lee,et al.  Flavonoids inhibit histamine release and expression of proinflammatory cytokines in mast cells , 2008, Archives of pharmacal research.

[32]  I. Chessell,et al.  Direct labelling of the human P2X7 receptor and identification of positive and negative cooperativity of binding , 2007, British journal of pharmacology.

[33]  D. Donnelly-roberts,et al.  A-740003 [N-(1-{[(Cyanoimino)(5-quinolinylamino) methyl]amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide], a Novel and Selective P2X7 Receptor Antagonist, Dose-Dependently Reduces Neuropathic Pain in the Rat , 2006, Journal of Pharmacology and Experimental Therapeutics.

[34]  H. Bouriche,et al.  Anti-inflammatory effect of rutin on rat paw oedema, and on neutrophils chemotaxis and degranulation. , 2003, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

[35]  U. Mohammed,et al.  Naturally occurring polyphenolic antioxidants modulate IgE‐mediated mast cell activation , 2000, Immunology.