论文信息 - Colonization of Multi-drug Resistant Bacteria in Chronic Neurological Disease Patients in Respite Care: Active Surveillance Study

Colonization of Multi-drug Resistant Bacteria in Chronic Neurological Disease Patients in Respite Care: Active Surveillance Study

Active surveillance was performed to determine the prevalence of multidrug-resistant bacteria in patients with chronic neurological disease who were under respite care. Twenty-six patients were enrolled between April 2010 and August 2014. Positive screening cultures were obtained from sputum samples in 20 patients and from urine samples in 24 patients. Staphylococcus aureus was detected in 8 patients, of whom 6 ( 75.0 ) had methicillin-resistant strains. Escherichia coli was detected in 9 patients ( 1 from sputum and 8 from urine ) , of whom 8 ( 88.9 ) showed resistance to ‰uoroquinolones. Extended-spectrum b -lactamase-producing Enterobacteriaceae were cultured from 9 patients ( 3 from sputum and 6 from urine ) . The medical devices frequently used to treat these patients were considered to be the sources of the multidrug-resistant colonization.

H. Kato | H. Hara | T. Nagai

[1] X. Nassif,et al. Risk factors for developing ESBL E. coli: can clinicians predict infection in patients with prior colonization? , 2013, The Journal of hospital infection.

[2] A. R. Hamzeh,et al. Resistance trends and risk factors of extended spectrum β-lactamases in Escherichia coli infections in Aleppo, Syria. , 2013, American journal of infection control.

[3] F. Rousset,et al. Emergence and dissemination of extended-spectrum beta-lactamase-producing Escherichia coli in the community: lessons from the study of a remote and controlled population. , 2010, The Journal of infectious diseases.

[4] M. Kollef. Broad-spectrum antimicrobials and the treatment of serious bacterial infections: getting it right up front. , 2008, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[5] P. Tambyah,et al. Engineering out the risk for infection with urinary catheters. , 2001, Emerging infectious diseases.

[6] Ann D. Zeigler,et al. Respiratory infection complicating long-term tracheostomy. The implication of persistent gram-negative tracheobronchial colonization. , 1984, Chest.