论文信息 - Dose Escalation and Up-and-Down Designs

Dose Escalation and Up-and-Down Designs

Up-and-down designs are dose-finding designs that are easy to use and understand. This article describes four main classes of up-and-down designs: biased coin, group, escalation, and A + B designs. The attention is focused on statistical properties of these designs. Keywords: dose finding; traditional design; A + B designs; group designs

Anastasia Ivanova

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