A retrospective analysis of RET translocation, gene copy number gain and expression in NSCLC patients treated with vandetanib in four randomized Phase III studies
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R. Herbst | P. Elvin | A. Platt | C. Womack | Q. Ji | N. Gray | J. Vasselli | X. Su | G. Bigley | R. D. de Boer | J. Read | C. Cresswell | Tianwei Zhang | Qingqing Ye | Li Zheng | L. Blockley | Jin-Soo Lee | Haihua Fu | Shuqiong Fan | E. Donald | J. Morten | Angela Dale | A. Davies | A. Gladwin | G. Harrod | J. Stevens | Victoria Williams | A. Dale | Jessica Read | Xinying Su
[1] C. Kang,et al. Diagnostic method for the detection of KIF5B-RET transformation in lung adenocarcinoma. , 2013, Lung cancer.
[2] Lu Wang,et al. Response to Cabozantinib in patients with RET fusion-positive lung adenocarcinomas. , 2013, Cancer discovery.
[3] P. Bunn,et al. RET rearrangements detected by FISH in "pan-negative" lung adenocarcinoma. , 2013 .
[4] S. Aebi,et al. A patient with lung adenocarcinoma and RET fusion treated with vandetanib. , 2013, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
[5] Caicun Zhou,et al. KIF5B‐RET fusions in Chinese patients with non–small cell lung cancer , 2013, Cancer.
[6] J. Ji,et al. FGFR2 Gene Amplification in Gastric Cancer Predicts Sensitivity to the Selective FGFR Inhibitor AZD4547 , 2013, Clinical Cancer Research.
[7] P. Jänne,et al. New targetable oncogenes in non-small-cell lung cancer. , 2013, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[8] H. Ji,et al. RET fusions define a unique molecular and clinicopathologic subtype of non-small-cell lung cancer. , 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[9] Hiroyuki Aburatani,et al. Identification of CCDC6-RET Fusion in the Human Lung Adenocarcinoma Cell Line, LC-2/ad , 2012, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
[10] Tatsuo Ito,et al. Identification of KIF5B-RET and GOPC-ROS1 Fusions in Lung Adenocarcinomas through a Comprehensive mRNA-Based Screen for Tyrosine Kinase Fusions , 2012, Clinical Cancer Research.
[11] H. Sasaki,et al. KIF5B/RET fusion gene in surgically-treated adenocarcinoma of the lung. , 2012, Oncology reports.
[12] H. Sasaki,et al. RET expression and detection of KIF5B/RET gene rearrangements in Japanese lung cancer , 2012, Cancer medicine.
[13] Identification of RET gene fusion by exon array analyses in “pan-negative” lung cancer from never smokers , 2012, Cell Research.
[14] Doron Lipson,et al. Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies , 2012, Nature Medicine.
[15] Seungbok Lee,et al. A transforming KIF5B and RET gene fusion in lung adenocarcinoma revealed from whole-genome and transcriptome sequencing. , 2012, Genome research.
[16] Yasushi Totoki,et al. KIF5B-RET fusions in lung adenocarcinoma , 2012, Nature Medicine.
[17] Yuki Togashi,et al. RET, ROS1 and ALK fusions in lung cancer , 2012, Nature Medicine.
[18] A. Tsao. Vandetanib Versus Placebo in Patients With Advanced Non–Small-Cell Lung Cancer After Prior Therapy With an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor: A Randomized, Double-Blind Phase III Trial (ZEPHYR) , 2012 .
[19] A. Wolff,et al. A phase II pharmacokinetic/pharmacogenetic (PK/PG) study using fixed-dose capecitabine in metastatic breast cancer (MBC). , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[20] Michael Thomas,et al. Phase III trial of vandetanib compared with erlotinib in patients with previously treated advanced non-small-cell lung cancer. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[21] Chih-Hsin Yang,et al. Vandetanib plus pemetrexed for the second-line treatment of advanced non-small-cell lung cancer: a randomized, double-blind phase III trial. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[22] Yan Sun,et al. Vandetanib plus docetaxel versus docetaxel as second-line treatment for patients with advanced non-small-cell lung cancer (ZODIAC): a double-blind, randomised, phase 3 trial. , 2010, The Lancet. Oncology.
[23] J. Vansteenkiste,et al. Vandetanib plus pemetrexed versus pemetrexed as second-line therapy in patients with advanced non-small cell lung cancer (NSCLC): A randomized, double-blind phase III trial (ZEAL). , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[24] A. Pinchera,et al. Prognostic significance of somatic RET oncogene mutations in sporadic medullary thyroid cancer: a 10-year follow-up study. , 2008, The Journal of clinical endocrinology and metabolism.
[25] C. Hedinger,et al. Papillary thyroid carcinomas , 1982, Virchows Archiv A.
[26] G. Fontanini,et al. ZD6474, an orally available inhibitor of KDR tyrosine kinase activity, efficiently blocks oncogenic RET kinases. , 2002, Cancer research.
[27] B. Curry,et al. ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration. , 2002, Cancer research.
[28] P. Goodfellow,et al. Single missense mutation in the tyrosine kinase catalytic domain of the RET protooncogene is associated with multiple endocrine neoplasia type 2B. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[29] P. Goodfellow,et al. Mutations in the RET proto-oncogene are associated with MEN 2A and FMTC. , 1993, Human molecular genetics.
[30] B. Ponder,et al. Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A , 1993, Nature.
[31] M. Borrello,et al. Identification of the product of two oncogenic rearranged forms of the RET proto-oncogene in papillary thyroid carcinomas. , 1992, Oncogene.