MeCP2 binds to 5hmc enriched within active genes and accessible chromatin in the nervous system
暂无分享,去创建一个
[1] G. Hon,et al. Base-Resolution Analysis of 5-Hydroxymethylcytosine in the Mammalian Genome , 2012, Cell.
[2] Michael L. Gonzales,et al. Phosphorylation of Distinct Sites in MeCP2 Modifies Cofactor Associations and the Dynamics of Transcriptional Regulation , 2012, Molecular and Cellular Biology.
[3] S. Balasubramanian,et al. Quantitative Sequencing of 5-Methylcytosine and 5-Hydroxymethylcytosine at Single-Base Resolution , 2012, Science.
[4] James C. Cronk,et al. Wild type microglia arrest pathology in a mouse model of Rett syndrome , 2012, Nature.
[5] B. Gowen,et al. MeCP2 binds to nucleosome free (linker DNA) regions and to H3K9/H3K27 methylated nucleosomes in the brain , 2011, Nucleic acids research.
[6] Poshen B. Chen,et al. Mbd3/NURD Complex Regulates Expression of 5-Hydroxymethylcytosine Marked Genes in Embryonic Stem Cells , 2011, Cell.
[7] Peng Jin,et al. 5-hmC–mediated epigenetic dynamics during postnatal neurodevelopment and aging , 2011, Nature Neuroscience.
[8] S. Nelson,et al. MeCP2: Phosphorylated Locally, Acting Globally , 2011, Neuron.
[9] Harrison W. Gabel,et al. Genome-Wide Activity-Dependent MeCP2 Phosphorylation Regulates Nervous System Development and Function , 2011, Neuron.
[10] Chuan He,et al. Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine , 2011, Science.
[11] J. Raber,et al. A role for glia in the progression of Rett’s syndrome , 2011, Nature.
[12] A. Klein-Szanto,et al. Thymine DNA Glycosylase Is Essential for Active DNA Demethylation by Linked Deamination-Base Excision Repair , 2011, Cell.
[13] Philipp Kapranov,et al. Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells , 2011, Nature.
[14] P. Georgel,et al. MeCP2: structure and function. , 2011, Biochemistry and cell biology = Biochimie et biologie cellulaire.
[15] P. Jin,et al. Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine , 2011, Nature Biotechnology.
[16] Jim Selfridge,et al. The role of MeCP2 in the brain. , 2009, Annual review of cell and developmental biology.
[17] Ralf Herwig,et al. Computational analysis of genome-wide DNA methylation during the differentiation of human embryonic stem cells along the endodermal lineage. , 2010, Genome research.
[18] H. Leonhardt,et al. Sensitive enzymatic quantification of 5-hydroxymethylcytosine in genomic DNA , 2010, Nucleic acids research.
[19] Tatiana Nikitina,et al. MeCP2 Binds Cooperatively to Its Substrate and Competes with Histone H1 for Chromatin Binding Sites , 2010, Molecular and Cellular Biology.
[20] M. Biel,et al. Quantification of the sixth DNA base hydroxymethylcytosine in the brain. , 2010, Angewandte Chemie.
[21] Swati Kadam,et al. Examination of the specificity of DNA methylation profiling techniques towards 5-methylcytosine and 5-hydroxymethylcytosine , 2010, Nucleic acids research.
[22] W. Huber,et al. which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. MAnorm: a robust model for quantitative comparison of ChIP-Seq data sets , 2011 .
[23] Robert S. Illingworth,et al. Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state. , 2010, Molecular cell.
[24] P. Greengard,et al. Writing Memories with Light-Addressable Reinforcement Circuitry , 2009, Cell.
[25] Robert Gentleman,et al. ShortRead: a bioconductor package for input, quality assessment and exploration of high-throughput sequence data , 2009, Bioinform..
[26] David R. Liu,et al. Conversion of 5-Methylcytosine to 5- Hydroxymethylcytosine in Mammalian DNA by the MLL Partner TET1 , 2009 .
[27] N. Heintz,et al. The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain , 2009, Science.
[28] Christina Thaller,et al. Mouse models of MeCP2 disorders share gene expression changes in the cerebellum and hypothalamus , 2009, Human molecular genetics.
[29] Hao Wu,et al. Deciphering Rett syndrome with mouse genetics, epigenomics, and human neurons. , 2009, International review of neurobiology.
[30] P. Greengard,et al. A Translational Profiling Approach for the Molecular Characterization of CNS Cell Types , 2008, Cell.
[31] B. Williams,et al. Mapping and quantifying mammalian transcriptomes by RNA-Seq , 2008, Nature Methods.
[32] Stephen T. C. Wong,et al. MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription , 2008, Science.
[33] W. Kaufmann,et al. Investigating genotype–phenotype relationships in Rett syndrome using an international data set , 2008, Neurology.
[34] Huda Y. Zoghbi,et al. The Story of Rett Syndrome: From Clinic to Neurobiology , 2007, Neuron.
[35] S. Jacobsen,et al. UHRF1 Plays a Role in Maintaining DNA Methylation in Mammalian Cells , 2007, Science.
[36] Allan R. Jones,et al. Genome-wide atlas of gene expression in the adult mouse brain , 2007, Nature.
[37] M. Fraga,et al. A profile of methyl-CpG binding domain protein occupancy of hypermethylated promoter CpG islands of tumor suppressor genes in human cancer. , 2006, Cancer research.
[38] M. Gorenstein,et al. Absolute Quantification of Proteins by LCMSE , 2006, Molecular & Cellular Proteomics.
[39] W. Lam,et al. Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells , 2005, Nature Genetics.
[40] Jan-Fang Cheng,et al. Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome , 2005, Nature Genetics.
[41] Alok J. Saldanha,et al. Java Treeview - extensible visualization of microarray data , 2004, Bioinform..
[42] A. Bird,et al. MeCP2 Behaves as an Elongated Monomer That Does Not Stably Associate with the Sin3a Chromatin Remodeling Complex* , 2004, Journal of Biological Chemistry.
[43] Jean YH Yang,et al. Bioconductor: open software development for computational biology and bioinformatics , 2004, Genome Biology.
[44] W. Lange,et al. Cell number and cell density in the cerebellar cortex of man and some other mammals , 2004, Cell and Tissue Research.
[45] A. Bird,et al. Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2). , 2004, Nucleic acids research.
[46] Eric C. Griffith,et al. Derepression of BDNF Transcription Involves Calcium-Dependent Phosphorylation of MeCP2 , 2003, Science.
[47] M. Nakao,et al. Heterogeneity in residual function of MeCP2 carrying missense mutations in the methyl CpG binding domain , 2003, Journal of medical genetics.
[48] J. Zlatanova,et al. DNA methylation‐dependent chromatin fiber compaction in vivo and in vitro: requirement for linker histone , 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[49] M. Pfaffl,et al. A new mathematical model for relative quantification in real-time RT-PCR. , 2001, Nucleic acids research.
[50] A. Bird,et al. A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome , 2001, Nature Genetics.
[51] H. Zoghbi,et al. Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2 , 1999, Nature Genetics.
[52] A. Wolffe,et al. The methyl-CpG binding transcriptional repressor MeCP2 stably associates with nucleosomal DNA. , 1999, Biochemistry.
[53] A. Shevchenko,et al. Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. , 1996, Analytical chemistry.
[54] A. Bird,et al. Binding of Histone H1 to DNA Is Indifferent to Methylation at CpG Sequences (*) , 1995, The Journal of Biological Chemistry.
[55] S. Palay,et al. Cerebellar Cortex: Cytology and Organization , 1974 .