Experiences with a sac-type artificial heart.

A total replacement artificial heart is described having in vitro performance satisfying human requirements up to and including moderate work.The in vitro design has been modified to make its implantation into the chests of experimental animals technically feasible.The heart has been tested in vivo for up to six hours, and has been found to provide the experimental animals with adequate blood flow and pressures.Preliminary tests have shown major problems of air embolism and red blood cell hemolysis.The heart design and technique of implantation are undergoing further improvement. Performance will be more comprehensively examined with the use of larger experimental animals in order more accurately to evaluate the heart's potential.

[1]  W. Kolff.  An artificial heart inside the body. , 1965, Scientific American.

[2]  T. Akutsu,et al.  A SAC TYPE OF ARTIFICIAL HEART INSIDE THE CHEST OF DOGS. , 1964, The Journal of thoracic and cardiovascular surgery.

[3]  T. Akutsu,et al.  Pendulum type of artificial heart within the chest: preliminiary report. , 1960, American heart journal.

[4]  T. Akutsu,et al.  Total artificial hearts with built-in valves. , 1970, Transactions - American Society for Artificial Internal Organs.

[5]  W. Kolff,et al.  A prosthetic heart with hemispherical ventricles designed for low hemolytic action. , 1970, Transactions - American Society for Artificial Internal Organs.

[6]  Robinson Tc,et al.  The development of an implanted left ventricular assist device and Rankine cycle power systems. , 1970 .

[7]  W. Kolff,et al.  Some experiences with artificial hearts inside the chest, driven with a simple inexpensive servo-system. , 1968, The Journal of cardiovascular surgery.

[8]  M. Klain,et al.  Elimination of some problems encountered in total replacement of the heart with an intrathoracic mechanical pump: venous return. , 1966, Transactions - American Society for Artificial Internal Organs.

[9]  T. Akutsu,et al.  Results obtained with artificial hearts driven by the N.A.S.A. servomechanism and the pathologic physiology of artificial hearts. , 1962, Transactions - American Society for Artificial Internal Organs.

[10]  T. Akutsu,et al.  Air-driven artificial hearts inside the chest. , 1961, Transactions - American Society for Artificial Internal Organs.