Real-time cardiac surface tracking from sparse samples using subspace clustering and maximum-likelihood linear regressors

Cardiac minimal invasive surgeries such as catheter based radio frequency ablation of atrial fibrillation requires high-precision tracking of inner cardiac surfaces in order to ascertain constant electrode-surface contact. Majority of cardiac motion tracking systems are either limited to outer surface or track limited slices/sectors of inner surface in echocardiography data which are unrealizable in MIS due to the varying resolution of ultrasound with depth and speckle effect. In this paper, a system for high accuracy real-time 3D tracking of both cardiac surfaces using sparse samples of outer-surface only is presented. This paper presents a novel approach to model cardiac inner surface deformations as simple functions of outer surface deformations in the spherical harmonic domain using multiple maximal-likelihood linear regressors. Tracking system uses subspace clustering to identify potential deformation spaces for outer surfaces and trains ML linear regressors using pre-operative MRI/CT scan based training set. During tracking, sparse-samples from outer surfaces are used to identify the active outer surface deformation space and reconstruct outer surfaces in real-time under least squares formulation. Inner surface is reconstructed using tracked outer surface with trained ML linear regressors. High-precision tracking and robustness of the proposed system are demonstrated through results obtained on a real patient dataset with tracking root mean square error ≤ (0.23 ± 0.04)mm and ≤ (0.30 ± 0.07)mm for outer & inner surfaces respectively.

[1]  Ahmed H. Tewfik,et al.  A real-time cardiac surface tracking system using Subspace Clustering , 2010, 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology.

[2]  Chao Liu,et al.  Three-dimensional Motion Tracking for Beating Heart Surgery Using a Thin-plate Spline Deformable Model , 2010, Int. J. Robotics Res..

[3]  Radford M. Neal Pattern Recognition and Machine Learning , 2007, Technometrics.

[4]  Fredrik Orderud,et al.  Real-Time Tracking of the Left Ventricle in 3D Echocardiography Using a State Estimation Approach , 2007, MICCAI.

[5]  Ahmed H. Tewfik,et al.  A Novel Subspace Clustering Method for Dictionary Design , 2009, ICA.

[6]  Michel Couprie,et al.  An open, clinically-validated database of 3D+t cine-MR images of the left ventricle with associated manual and automated segmentation , 2007, The Insight Journal.

[7]  Edouard Laroche,et al.  Motion Prediction for Computer-Assisted Beating Heart Surgery , 2009, IEEE Transactions on Biomedical Engineering.

[8]  Dan Wang,et al.  Real time tracking of exterior and interior organ surfaces using sparse sampling of the exterior surfaces , 2010, 2010 IEEE International Conference on Acoustics, Speech and Signal Processing.

[9]  Fillia Makedon,et al.  A Spatio-Temporal Modeling Method for Shape Representation , 2006, Third International Symposium on 3D Data Processing, Visualization, and Transmission (3DPVT'06).

[10]  Dan Wang,et al.  In vivo tracking of 3D organs using spherical harmonics and subspace clustering , 2009, 2009 16th IEEE International Conference on Image Processing (ICIP).

[11]  Fillia Makedon,et al.  Surface Alignment of 3D Spherical Harmonic Models: Application to Cardiac MRI Analysis , 2005, MICCAI.

[12]  Guido Gerig,et al.  Parametrization of Closed Surfaces for 3-D Shape Description , 1995, Comput. Vis. Image Underst..