Semi‐automated imaging system to quantitate Her‐2/neu membrane receptor immunoreactivity in human breast cancer

Immunocytochemical methods for quantitating Her‐2/neu immunoreactivity rest on subjective semi‐quantitative interpretations with resulting interobserver, intraobserver, and fatigue variability.

[1]  K. Pienta,et al.  Tissue Microarray Sampling Strategy for Prostate Cancer Biomarker Analysis , 2002, The American journal of surgical pathology.

[2]  Edith A Perez,et al.  Advances in adjuvant therapy for breast cancer. , 2006, Clinical advances in hematology & oncology : H&O.

[3]  Sankar K. Pal,et al.  Image segmentation using fuzzy correlation , 1992, Inf. Sci..

[4]  K H Chuang,et al.  IMPACT: Image‐based physiological artifacts estimation and correction technique for functional MRI , 2001, Magnetic resonance in medicine.

[5]  J. Ploem,et al.  A simple method to select specific tumor areas in paraffin blocks for cytometry using incident fluorescence microscopy. , 1986, Cytometry.

[6]  C. Frith,et al.  Movement and Mind: A Functional Imaging Study of Perception and Interpretation of Complex Intentional Movement Patterns , 2000, NeuroImage.

[7]  C. D'Orsi,et al.  Diagnostic Performance of Digital Versus Film Mammography for Breast-Cancer Screening , 2005, The New England journal of medicine.

[8]  T. Lörch,et al.  Quantitative analysis of disseminated tumor cells in the bone marrow by automated fluorescence image analysis. , 2000, Cytometry.

[9]  Anil K. Jain.  Fundamentals of Digital Image Processing , 2018, Control of Color Imaging Systems.

[10]  E L Siegel,et al.  Effect of filmless imaging on the utilization of radiologic services. , 2000, Radiology.

[11]  D. Arnold,et al.  Modeling in vivo recovery of intracellular pH in muscle to provide a novel index of proton handling: Application to the diagnosis of mitochondrial myopathy , 2001, Magnetic resonance in medicine.

[12]  M. Begnami,et al.  Antigen Retrieval Methods and Estrogen Receptor Immunoexpression Using 1D5 Antibody: A Comparative Study , 2005, International journal of surgical pathology.

[13]  L L Houston,et al.  Avidity-Mediated Enhancement of In vivo Tumor Targeting by Single-Chain Fv Dimers , 2006, Clinical Cancer Research.

[14]  R. Finn,et al.  Monoclonal antibody therapy for breast cancer: herceptin. , 2003, Cancer chemotherapy and biological response modifiers.