Tumor immunogenicity dictates reliance on TCF1 in CD8+ T cells for response to immunotherapy.
暂无分享,去创建一个
L. Biasco | C. Jewell | Katherine Tooley | A. Anderson | Michelle L. Bookstaver | Giulia Escobar | C. Rutigliani | Eugene Froimchuk | Linglin Huang | D. Mangani | C. Edwards | Joan Pagès Oliveras | Hanning Cheng | Chang Xue | Rajesh K Krishnan | Natanael Hazel
[1] J. Wolchok,et al. Clinical implications of T cell exhaustion for cancer immunotherapy , 2022, Nature Reviews Clinical Oncology.
[2] V. Buchholz,et al. MYB orchestrates T cell exhaustion and response to checkpoint inhibition , 2022, Nature.
[3] Charles H. Yoon,et al. An activation to memory differentiation trajectory of tumor-infiltrating lymphocytes informs metastatic melanoma outcomes. , 2022, Cancer cell.
[4] C. Zang,et al. Tcf1 preprograms the mobilization of glycolysis in central memory CD8+ T cells during recall responses , 2022, Nature Immunology.
[5] A. Bhutkar,et al. Type I interferon activates MHC class I-dressed CD11b+ conventional dendritic cells to promote protective anti-tumor CD8+ T cell immunity. , 2021, Immunity.
[6] C. Yun,et al. Self-reactivity controls functional diversity of naive CD8+ T cells by co-opting tonic type I interferon , 2021, Nature Communications.
[7] Nikhil S. Joshi,et al. A reservoir of stem-like CD8+ T cells in the tumor-draining lymph node preserves the ongoing antitumor immune response , 2021, Science Immunology.
[8] A. Regev,et al. Conventional type I dendric cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes. , 2021, Immunity.
[9] Christopher C. Griffith,et al. Functional HPV-specific PD-1+ stem-like CD8 T cells in head and neck cancer , 2021, Nature.
[10] D. Irvine,et al. Low neoantigen expression and poor T-cell priming underlie early immune escape in colorectal cancer , 2021, Nature Cancer.
[11] Santiago J. Carmona,et al. Interpretation of T cell states from single-cell transcriptomics data using reference atlases , 2021, Nature Communications.
[12] Timothy J. Peters,et al. Antigen-driven EGR2 expression is required for exhausted CD8+ T cell stability and maintenance , 2021, Nature Communications.
[13] C. Jewell,et al. Altering Antigen Charge to Control Self-Assembly and Processing of Immune Signals During Cancer Vaccination , 2021, Frontiers in Immunology.
[14] P. Catalano,et al. Expression of T-Cell Exhaustion Molecules and Human Endogenous Retroviruses as Predictive Biomarkers for Response to Nivolumab in Metastatic Clear Cell Renal Cell Carcinoma , 2020, Clinical Cancer Research.
[15] A. Anderson,et al. T cell factor 1: A master regulator of the T cell response in disease , 2020, Science Immunology.
[16] Raphael Gottardo,et al. Integrated analysis of multimodal single-cell data , 2020, Cell.
[17] S. Thomas,et al. Blockade of immune checkpoints in lymph nodes through locoregional delivery augments cancer immunotherapy , 2020, Science Translational Medicine.
[18] L. Boon,et al. The PD-1/PD-L1-Checkpoint Restrains T cell Immunity in Tumor-Draining Lymph Nodes. , 2020, Cancer cell.
[19] D. Ye,et al. Identification of new susceptibility loci associated with rheumatoid arthritis , 2020, Annals of the Rheumatic Diseases.
[20] M. Mann,et al. Dynamics in protein translation sustaining T cell preparedness , 2020, Nature Immunology.
[21] G. Freeman,et al. Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1+ Stem-like CD8+ T Cells during Chronic Infection. , 2019, Immunity.
[22] David M. Schauder,et al. CD4+ T Cell Help Is Required for the Formation of a Cytolytic CD8+ T Cell Subset that Protects against Chronic Infection and Cancer. , 2019, Immunity.
[23] Howard Y. Chang,et al. c-Jun overexpression in CAR T cells induces exhaustion resistance , 2019, Nature.
[24] S. Berger,et al. TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision. , 2019, Immunity.
[25] W. Birchmeier,et al. SHP-2 in Lymphocytes' Cytokine and Inhibitory Receptor Signaling , 2019, Front. Immunol..
[26] Simon C. Potter,et al. Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility , 2019, Science.
[27] G. Freeman,et al. Intratumoral Activity of the CXCR3 Chemokine System Is Required for the Efficacy of Anti-PD-1 Therapy. , 2019, Immunity.
[28] M. Delorenzi,et al. TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection , 2019, Nature.
[29] Yong Liu,et al. TOX is a critical regulator of tumour-specific T cell differentiation , 2019, Nature.
[30] S. Berger,et al. TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion , 2019, Nature.
[31] P. Hogan,et al. TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8+ T cell exhaustion , 2019, Proceedings of the National Academy of Sciences.
[32] Vinay Prasad,et al. Estimation of the Percentage of US Patients With Cancer Who Are Eligible for and Respond to Checkpoint Inhibitor Immunotherapy Drugs , 2019, JAMA network open.
[33] Elisabeth F. Heuston,et al. Single-Cell RNA-Seq Reveals TOX as a Key Regulator of CD8+ T cell Persistence in Chronic Infection , 2019, Nature Immunology.
[34] F. Hodi,et al. Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade , 2019, Nature Immunology.
[35] I. Amit,et al. Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma , 2019, Cell.
[36] Aviv Regev,et al. Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD‐1−CD8+ Tumor‐Infiltrating T Cells , 2019, Immunity.
[37] Daniel E. Speiser,et al. Intratumoral Tcf1+PD‐1+CD8+ T Cells with Stem‐like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy , 2019, Immunity.
[38] Paul J. Hoover,et al. Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma , 2019, Cell.
[39] M. Kneilling,et al. Tumor-draining lymph nodes are pivotal in PD-1/PD-L1 checkpoint therapy. , 2018, JCI insight.
[40] Ralph Weissleder,et al. Successful Anti‐PD‐1 Cancer Immunotherapy Requires T Cell‐Dendritic Cell Crosstalk Involving the Cytokines IFN‐&ggr; and IL‐12 , 2018, Immunity.
[41] Francesco Ferrari,et al. High-dimensional single cell analysis identifies stem-like cytotoxic CD8+ T cells infiltrating human tumors , 2018, The Journal of experimental medicine.
[42] C. Klein,et al. A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small cell lung cancer treated with PD-1 blockade , 2018, Nature Medicine.
[43] L. Coussens,et al. TIM-3 Regulates CD103+ Dendritic Cell Function and Response to Chemotherapy in Breast Cancer. , 2018, Cancer cell.
[44] J. Aerts,et al. SCENIC: Single-cell regulatory network inference and clustering , 2017, Nature Methods.
[45] Sean C. Bendall,et al. Systemic Immunity Is Required for Effective Cancer Immunotherapy , 2017, Cell.
[46] Aviv Regev,et al. A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells , 2016, Cell.
[47] Avinash Bhandoola,et al. TCF-1 upregulation identifies early innate lymphoid progenitors in the bone marrow , 2015, Nature Immunology.
[48] P. Rochaix,et al. Blocking Tumor Necrosis Factor α Enhances CD8 T-cell-Dependent Immunity in Experimental Melanoma. , 2015, Cancer research.
[49] H. Koblish,et al. Mechanism of tumor rejection with doublets of CTLA-4, PD-1/PD-L1, or IDO blockade involves restored IL-2 production and proliferation of CD8+ T cells directly within the tumor microenvironment , 2014, Journal of Immunotherapy for Cancer.
[50] M. Pirinen,et al. Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis , 2013, Nature Genetics.
[51] Ludo Waltman,et al. A smart local moving algorithm for large-scale modularity-based community detection , 2013, The European Physical Journal B.
[52] Xavier Robin,et al. pROC: an open-source package for R and S+ to analyze and compare ROC curves , 2011, BMC Bioinformatics.
[53] J. Harty,et al. Differentiation and persistence of memory CD8(+) T cells depend on T cell factor 1. , 2010, Immunity.
[54] Dietmar Zehn,et al. Complete but curtailed T cell response to very low affinity antigen , 2009, Nature.
[55] L. Ailles,et al. Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences , 2000, Nature Genetics.
[56] K. Losos,et al. An enhancer that directs lineage-specific expression of CD8 in positively selected thymocytes and mature T cells. , 1997, Immunity.