RNA interference: potential therapeutic targets
暂无分享,去创建一个
S. Jana | J. K. Deb | S. Jana | C. Chakraborty | S. Nandi | C. Chakraborty | S. Nandi | S. Nandi | Chiranjib Chakraborty
[1] C. Napoli,et al. Introduction of a Chimeric Chalcone Synthase Gene into Petunia Results in Reversible Co-Suppression of Homologous Genes in trans. , 1990, The Plant cell.
[2] V. Ambros,et al. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14 , 1993, Cell.
[3] K. Kemphues,et al. par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed , 1995, Cell.
[4] G. Wang,et al. Induction of the , 1996 .
[5] R. Kucherlapati,et al. K-ras is an essential gene in the mouse with partial functional overlap with N-ras. , 1997, Genes & development.
[6] Jun Miyoshi,et al. K-Ras is essential for the development of the mouse embryo , 1997, Oncogene.
[7] A. Fire,et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans , 1998, Nature.
[8] C. Mello,et al. RNAi in C. elegans: Soaking in the Genome Sequence , 1998, Science.
[9] R. Plasterk,et al. mut-7 of C. elegans, Required for Transposon Silencing and RNA Interference, Is a Homolog of Werner Syndrome Helicase and RNaseD , 1999, Cell.
[10] Andrew Fire,et al. The rde-1 Gene, RNA Interference, and Transposon Silencing in C. elegans , 1999, Cell.
[11] Magdalena Zernicka-Goetz,et al. Specific interference with gene function by double-stranded RNA in early mouse development , 2000, Nature Cell Biology.
[12] K. Ui-Tei,et al. Sensitive assay of RNA interference in Drosophila and Chinese hamster cultured cells using firefly luciferase gene as target , 2000, FEBS letters.
[13] S. Hammond,et al. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells , 2000, Nature.
[14] Ronald H. A. Plasterk,et al. A genetic link between co-suppression and RNA interference in C. elegans , 2000, Nature.
[15] R. Carthew,et al. Heritable gene silencing in Drosophila using double-stranded RNA , 2000, Nature Biotechnology.
[16] P. Sharp,et al. RNAi Double-Stranded RNA Directs the ATP-Dependent Cleavage of mRNA at 21 to 23 Nucleotide Intervals , 2000, Cell.
[17] B. Reinhart,et al. The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans , 2000, Nature.
[18] Hagstrom Je. Self-assembling complexes for in vivo gene delivery. , 2000 .
[19] T. Tuschl,et al. RNA interference is mediated by 21- and 22-nucleotide RNAs. , 2001, Genes & development.
[20] V. Ambros,et al. An Extensive Class of Small RNAs in Caenorhabditis elegans , 2001, Science.
[21] A. Pasquinelli,et al. A Cellular Function for the RNA-Interference Enzyme Dicer in the Maturation of the let-7 Small Temporal RNA , 2001, Science.
[22] B. Kaang,et al. Overexpression of and RNA interference with the CCAAT enhancer-binding protein on long-term facilitation of Aplysia sensory to motor synapses. , 2001, Learning & memory.
[23] B. Bass,et al. A Role for the RNase III Enzyme DCR-1 in RNA Interference and Germ Line Development in Caenorhabditis elegans , 2001, Science.
[24] Debra Robertson,et al. US FTC probes practices of 100 companies , 2001, Nature Biotechnology.
[25] G. Hannon,et al. C . elegans involved in developmental timing in Dicer functions in RNA interference and in synthesis of small RNA , 2001 .
[26] A. Fire,et al. Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[27] A. Caudy,et al. Argonaute2, a Link Between Genetic and Biochemical Analyses of RNAi , 2001, Science.
[28] L. Lim,et al. An Abundant Class of Tiny RNAs with Probable Regulatory Roles in Caenorhabditis elegans , 2001, Science.
[29] A. Fire,et al. Distinct roles for RDE-1 and RDE-4 during RNA interference in Caenorhabditis elegans. , 2001, RNA.
[30] T. Tuschl,et al. Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate , 2001, The EMBO journal.
[31] A. Caudy,et al. Role for a bidentate ribonuclease in the initiation step of RNA interference , 2001 .
[32] P. Sharp,et al. RNA interference--2001. , 2001, Genes & development.
[33] K Weber,et al. Identification of essential genes in cultured mammalian cells using small interfering RNAs. , 2001, Journal of cell science.
[34] D. Jans,et al. Gene therapy: optimising DNA delivery to the nucleus. , 2001, Current drug targets.
[35] T. Tuschl,et al. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells , 2001, Nature.
[36] Brenda L. Bass,et al. RNA interference: The short answer , 2001, Nature.
[37] Pirmin Fessler,et al. References , 1974 .
[38] J. Birchler,et al. RNAi related mechanisms affect both transcriptional and posttranscriptional transgene silencing in Drosophila. , 2002, Molecular cell.
[39] E. Lai. Micro RNAs are complementary to 3′ UTR sequence motifs that mediate negative post-transcriptional regulation , 2002, Nature Genetics.
[40] T. Tuschl,et al. Identification of Tissue-Specific MicroRNAs from Mouse , 2002, Current Biology.
[41] David L. Lewis,et al. Efficient delivery of siRNA for inhibition of gene expression in postnatal mice , 2002, Nature Genetics.
[42] Stacy L DeRuiter,et al. RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[43] N. Caplen. A new approach to the inhibition of gene expression. , 2002, Trends in biotechnology.
[44] M. Stevenson,et al. Modulation of HIV-1 replication by RNA interference , 2002, Nature.
[45] Paul Ahlquist,et al. RNA-Dependent RNA Polymerases, Viruses, and RNA Silencing , 2002, Science.
[46] Ali Ehsani,et al. Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells , 2002, Nature Biotechnology.
[47] R. Bernards,et al. Stable suppression of tumorigenicity by virus-mediated RNA interference. , 2002, Cancer cell.
[48] Henning Urlaub,et al. Single-Stranded Antisense siRNAs Guide Target RNA Cleavage in RNAi , 2002, Cell.
[49] G. Hannon. RNA interference : RNA , 2002 .
[50] R. Bernards,et al. A System for Stable Expression of Short Interfering RNAs in Mammalian Cells , 2002, Science.
[51] Phillip D Zamore,et al. RNAi: nature abhors a double-strand. , 2002, Current opinion in genetics & development.
[52] K. Taira,et al. U6 promoter–driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells , 2002, Nature Biotechnology.
[53] R. Andino,et al. Short interfering RNA confers intracellular antiviral immunity in human cells , 2002, Nature.
[54] W. Forrester,et al. A DNA vector-based RNAi technology to suppress gene expression in mammalian cells , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[55] Haibin Xia,et al. siRNA-mediated gene silencing in vitro and in vivo , 2002, Nature Biotechnology.
[56] T. Giordano,et al. RNAi: gene-silencing in therapeutic intervention. , 2002, Drug discovery today.
[57] A. Fire,et al. Rescue of polyglutamine-mediated cytotoxicity by double-stranded RNA-mediated RNA interference. , 2002, Human molecular genetics.
[58] Douglas S. Conklin,et al. Gene expression: RNA interference in adult mice , 2002, Nature.
[59] Craig P. Hunter,et al. Systemic RNAi in C. elegans Requires the Putative Transmembrane Protein SID-1 , 2002, Science.
[60] K. Kosik,et al. RNAi functions in cultured mammalian neurons , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[61] R. Agami. RNAi and related mechanisms and their potential use for therapy. , 2002, Current opinion in chemical biology.
[62] R. Medzhitov,et al. Retroviral delivery of small interfering RNA into primary cells , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[63] V. Erdmann,et al. Comparison of different antisense strategies in mammalian cells using locked nucleic acids, 2'-O-methyl RNA, phosphorothioates and small interfering RNA. , 2003, Nucleic acids research.
[64] Judy Lieberman,et al. Interfering with disease: opportunities and roadblocks to harnessing RNA interference , 2003, Trends in Molecular Medicine.
[65] H. Paulson,et al. Toward therapy for DYT1 dystonia: Allele‐specific silencing of mutant TorsinA , 2003, Annals of neurology.
[66] G. Hannon,et al. RNAi: an ever-growing puzzle. , 2003, Trends in biochemical sciences.
[67] Michael T. McManus,et al. A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference , 2003, Nature Genetics.
[68] Mouldy Sioud,et al. Gene silencing by systemic delivery of synthetic siRNAs in adult mice. , 2003, Journal of molecular biology.
[69] Petr Svoboda,et al. RNAi: mammalian oocytes do it without RNA-dependent RNA polymerase. , 2003, RNA.
[70] Shelley R. Hough,et al. Why RNAi makes sense , 2003, Nature Biotechnology.
[71] H. Cerutti,et al. RNA interference: traveling in the cell and gaining functions? , 2003, Trends in genetics : TIG.
[72] A. Dillin. The specifics of small interfering RNA specificity , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[73] R. Iggo,et al. Induction of an interferon response by RNAi vectors in mammalian cells , 2003, Nature Genetics.
[74] M. Wood,et al. Therapeutic gene silencing in the nervous system. , 2003, Human molecular genetics.
[75] M. Wood,et al. Allele-specific silencing of a pathogenic mutant acetylcholine receptor subunit by RNA interference. , 2003, Human molecular genetics.
[76] M. Manns,et al. Caspase 8 small interfering RNA prevents acute liver failure in mice , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[77] E. Moss. Silencing unhealthy alleles naturally. , 2003, Trends in biotechnology.
[78] Haibin Xia,et al. Allele-specific silencing of dominant disease genes , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[79] Peter A. Jones,et al. Establishment of conditional vectors for hairpin siRNA knockdowns. , 2003, Nucleic acids research.
[80] Inder M Verma,et al. A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[81] V. Kim. RNA interference in functional genomics and medicine. , 2003, Journal of Korean medical science.
[82] J. Church,et al. siRNA-DIRECTED INHIBITION OF HIV-1 INFECTION , 2003, Pediatrics.
[83] H. Paulson,et al. For Personal Use. Only Reproduce with Permission the Lancet Publishing Group. Molecular Medicine for the Brain: Silencing of Disease Genes with Rna Interference , 2022 .
[84] N. Schütze. siRNA technology , 2004, Molecular and Cellular Endocrinology.
[85] C. Mobbs,et al. Lobotomy of genes: use of RNA interference in Neuroscience , 2004, Neuroscience.
[86] K. Tokunaga,et al. Long‐lasting RNAi activity in mammalian neurons , 2004, FEBS letters.
[87] R. Plasterk,et al. RNAi protects the Caenorhabditis elegans germline against transposition. , 2004, Trends in genetics : TIG.
[88] M. Esteban,et al. Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): Mechanism of action , 2000, Apoptosis.
[89] R. Bhatnagar,et al. siRNA-directed silencing of transgene expressed in cultured insect cells. , 2004, Biochemical and biophysical research communications.
[90] A. Gartel,et al. RNA interference as a new strategy against viral hepatitis. , 2004, Virology.
[91] John J Rossi,et al. Control of HIV-1 replication by RNA interference. , 2004, Virus research.
[92] K. Jain. RNAi and siRNA in target validation. , 2004, Drug discovery today.
[93] R. Plasterk,et al. Dicers at RISC The Mechanism of RNAi , 2004, Cell.