Drosophila melanogaster deoxyribonucleoside kinase activates gemcitabine.
暂无分享,去创建一个
H. Eklund | J. Piškur | A. Clausen | W. Knecht | Z. Gojkovic | N. Mikkelsen | Mette Willer | Z. Gojković
[1] H. Eklund,et al. Structural studies of nucleoside analog and feedback inhibitor binding to Drosophila melanogaster multisubstrate deoxyribonucleoside kinase , 2008, The FEBS journal.
[2] M. Konrad,et al. Mimicking phosphorylation of Ser‐74 on human deoxycytidine kinase selectively increases catalytic activity for dC and dC analogues , 2008, FEBS letters.
[3] J. Piškur,et al. Drosophila deoxyribonucleoside kinase mutants with enhanced ability to phosphorylate purine analogs , 2007, Gene Therapy.
[4] C. Galmarini,et al. Gemcitabine resistance due to deoxycytidine kinase deficiency can be reverted by fruitfly deoxynucleoside kinase, DmdNK, in human uterine sarcoma cells , 2006, Cancer Chemotherapy and Pharmacology.
[5] F. Cappuzzo,et al. Role of gemcitabine in cancer therapy. , 2005, Future oncology.
[6] G. Petersen,et al. Mosquito has a single multisubstrate deoxyribonucleoside kinase characterized by unique substrate specificity. , 2003, Nucleic acids research.
[7] H. Eklund,et al. A few amino acid substitutions can convert deoxyribonucleoside kinase specificity from pyrimidines to purines , 2002, The EMBO journal.
[8] G. Petersen,et al. Deoxyribonucleoside kinases belonging to the thymidine kinase 2 (TK2)-like group vary significantly in substrate specificity, kinetics and feed-back regulation. , 2002, Journal of molecular biology.
[9] H. Eklund,et al. Structural basis for substrate specificities of cellular deoxyribonucleoside kinases , 2001, Nature Structural Biology.
[10] A. Karlsson,et al. Retroviral Transduction of Cancer Cell Lines with the Gene Encoding Drosophila melanogaster Multisubstrate Deoxyribonucleoside Kinase* , 2000, The Journal of Biological Chemistry.
[11] J. Piškur,et al. Identification of residues involved in the specificity and regulation of the highly efficient multisubstrate deoxyribonucleoside kinase from Drosophila melanogaster. , 2000, Journal of molecular biology.
[12] J. Piškur,et al. Functional Expression of a Multisubstrate Deoxyribonucleoside Kinase from Drosophila melanogaster and Its C-terminal Deletion Mutants* , 2000, The Journal of Biological Chemistry.
[13] J. Piškur,et al. Four Deoxynucleoside Kinase Activities from Drosophila melanogaster Are Contained within a Single Monomeric Enzyme, a New Multifunctional Deoxynucleoside Kinase* , 1998, The Journal of Biological Chemistry.
[14] B. Kirschbaum,et al. Functional expression of a fragment of human dihydroorotate dehydrogenase by means of the baculovirus expression vector system, and kinetic investigation of the purified recombinant enzyme. , 1996, European journal of biochemistry.
[15] Collaborative Computational,et al. The CCP4 suite: programs for protein crystallography. , 1994, Acta crystallographica. Section D, Biological crystallography.
[16] Z. Ram,et al. In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors. , 1992, Science.
[17] J. Zou,et al. Improved methods for building protein models in electron density maps and the location of errors in these models. , 1991, Acta crystallographica. Section A, Foundations of crystallography.
[18] F. Moolten. Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy. , 1986, Cancer research.
[19] P. Bohley,et al. Biochemical Nomenclature and Related Documents: International Union of Biochemistry Pergamon; New York, Oxford, 1978 vi + 224 pages , 1980 .
[20] P. Afonine,et al. research papers Acta Crystallographica Section D Biological , 2003 .
[21] Elias S. J. Arnér,et al. Mammalian deoxyribonucleoside kinases. , 1995, Pharmacology & therapeutics.