Effects of obesity on inflammation and lipid profile of obese women.

besity is known to be a contributing factor through inflammatory mediators to a wide array of disease, ranging from decreased life expectancy to cardiac disease, diabetes, and metabolic syndrome (MS). The chronic low-grade systemic inflammatory response is a major health concern in the life of obese patients. Adipose tissue is responsible for the secretion of cytokines, also known as adipokines, including tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6). The c-reactive protein (CRP) is another adipokine associated with obesity. Several studies have found that the inflammation present in obesity is associated with a significantly increased CRP level in obese people compared to non-obese people.