Knockout Mice Reveal Opposite Roles for Serotonin 1A and 1B Receptors in Prepulse Inhibition

[1]  R. Hen,et al.  Complications associated with genetic background effects in research using knockout mice , 1999, Psychopharmacology.

[2]  R. Hen,et al.  Altered Emotional States in Knockout Mice Lacking 5-HT1A or 5-HT1B Receptors , 1999, Neuropsychopharmacology.

[3]  M. Geyer,et al.  Opposite effects of 3,4-methylenedioxymethamphetamine (MDMA) on sensorimotor gating in rats versus healthy humans , 1999, Psychopharmacology.

[4]  L H Parsons,et al.  Elevated anxiety and antidepressant-like responses in serotonin 5-HT1A receptor mutant mice. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[5]  M. Geyer,et al.  5‐HT1B Receptor Modulation of Prepulse Inhibition: Recent Findings in Wild‐type and 5‐HT1B Knockout Mice a , 1998, Annals of the New York Academy of Sciences.

[6]  R Hen,et al.  Serotonin receptor 1A knockout: an animal model of anxiety-related disorder. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[7]  M Toth,et al.  Increased anxiety of mice lacking the serotonin1A receptor. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[8]  R. Hen,et al.  Novel strategies to probe the functions of serotonin receptors , 1998, Biological Psychiatry.

[9]  R. Hen,et al.  Insights into the Neurobiology of Impulsive Behavior from Serotonin Receptor Knockout Mice , 1997, Annals of the New York Academy of Sciences.

[10]  M. Geyer,et al.  Serotonin1B receptor modulation of startle reactivity, habituation, and prepulse inhibition in wild-type and serotonin1B knockout mice , 1997, Psychopharmacology.

[11]  M. Geyer,et al.  DOI disrupts prepulse inhibition of startle in rats via 5-HT2A receptors in the ventral pallidum , 1997, Brain Research.

[12]  S. Ying,et al.  5-HT7 receptors mediate serotonergic effects on light-sensitive suprachiasmatic nucleus neurons , 1997, Brain Research.

[13]  G. Bertschy,et al.  Long-term treatment of depression: is there a use for depot antidepressants? , 1997, International Clinical Psychopharmacology.

[14]  M. Geyer,et al.  Psychopharmacology of prepulse inhibition in mice. , 1996, The Chinese journal of physiology.

[15]  M. Koch The septohippocampal system is involved in prepulse inhibition of the acoustic startle response in rats. , 1996, Behavioral neuroscience.

[16]  N. Swerdlow Serotonin, obsessive compulsive disorder and the basal ganglia , 1995 .

[17]  E. Daneluzzo,et al.  Sensorimotor gating and habituation evoked by electro-cutaneous stimulation in schizophrenia , 1994, Biological Psychiatry.

[18]  R Hen,et al.  Enhanced aggressive behavior in mice lacking 5-HT1B receptor. , 1994, Science.

[19]  A. Tsou,et al.  Cloning and Expression of a 5‐Hydroxytryptamine7 Receptor Positively Coupled to Adenylyl Cyclase , 1994, Journal of neurochemistry.

[20]  R. Hen,et al.  The mouse 5-hydroxytryptamine 1B receptor is localized predominantly on axon terminals , 1994, Neuroscience.

[21]  M. Galvan,et al.  Differential effects of centrally‐active antihypertensives on 5‐HT1A receptors in rat dorso‐lateral septum, rat hippocampus and guinea‐pig hippocampus , 1994, British journal of pharmacology.

[22]  M. Geyer,et al.  Impaired startle prepulse inhibition and habituation in patients with schizotypal personality disorder. , 1993, The American journal of psychiatry.

[23]  P. Grof,et al.  An open study of oral flesinoxan, a 5‐HT1A receptor agonist, in treatment‐resistant depression , 1993, International clinical psychopharmacology.

[24]  G. Rigdon,et al.  5-Hydroxytryptamine 1a receptor agonists block prepulse inhibition of acoustic startle reflex. , 1992, The Journal of pharmacology and experimental therapeutics.

[25]  M. Hamon,et al.  Anpirtoline, a novel, highly potent 5‐HT1B receptor agonist with antinociceptive/antidepressant‐like actions in rodents , 1992, British journal of pharmacology.

[26]  Christian Grillon,et al.  Gating and habituation of the startle reflex in schizophrenic patients. , 1992 .

[27]  N. Swerdlow,et al.  The neural substrates of sensorimotor gating of the startle reflex: a review of recent findings and their implications , 1992, Journal of psychopharmacology.

[28]  M. Pompeiano,et al.  Distribution and cellular localization of mRNA coding for 5-HT1A receptor in the rat brain: correlation with receptor binding , 1992, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[29]  R. Hen,et al.  Of mice and flies: commonalities among 5-HT receptors. , 1992, Trends in pharmacological sciences.

[30]  J. Kehne,et al.  Effects of the serotonin releasers 3,4-methylenedioxymethamphetamine (MDMA), 4-chloroamphetamine (PCA) and fenfluramine on acoustic and tactile startle reflexes in rats. , 1992, The Journal of pharmacology and experimental therapeutics.

[31]  N. Swerdlow,et al.  GABAergic projection from nucleus accumbers to ventral pallidum mediates dopamine-induced sensorimotor gating deficits of acoustic startle in rats , 1990, Brain Research.

[32]  L. Lanfumey,et al.  The main features of central 5-HT1 receptors. , 1990, Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.

[33]  M. Geyer,et al.  Prepulse inhibition of the acoustic startle response is disrupted by N-ethyl-3,4-methylenedioxyamphetamine (MDEA) in the rat. , 1989, European journal of pharmacology.

[34]  D. Hoyer,et al.  Centrally acting hypotensive agents with affinity for 5‐HT1A binding sites inhibit forskolin‐stimulated adenylate cyclase activity in calf hippocampus , 1988, British journal of pharmacology.

[35]  M. Geyer,et al.  Habituation of tactile startle is altered by drugs acting on serotonin-2 receptors. , 1988, Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.

[36]  J. Palacios,et al.  Serotonin receptors in the human brain—IV. Autoradiographic mapping of serotonin-2 receptors , 1987, Neuroscience.

[37]  J. Palacios,et al.  Serotonin receptors in the human brain. I. Characterization and autoradiographic localization of 5-HT1A recognition sites. Apparent absence of 5-HT1B recognition sites , 1986, Brain Research.

[38]  P. Timmermans,et al.  Differential selectivities of RU 24969 and 8-OH-DPAT for the purported 5-HT1A and 5-HT1B binding sites. Correlation between 5-HT1A affinity and hypotensive activity. , 1985, European journal of pharmacology.

[39]  A. Frazer,et al.  Determination of selective and nonselective compounds for the 5-HT 1A and 5-HT 1B receptor subtypes in rat frontal cortex. , 1984, The Journal of pharmacology and experimental therapeutics.

[40]  M. Hamon,et al.  Autoradiographic evidence for the heterogeneity of 5-HT1 sites in the rat brain , 1984, Brain Research.

[41]  M. Geyer,et al.  Habituation of the Blink reflex in normals and schizophrenic patients. , 1982, Psychophysiology.

[42]  M. Geyer,et al.  Prestimulus effects on human startle reflex in normals and schizophrenics. , 1978, Psychophysiology.

[43]  F. Graham,et al.  Presidential Address, 1974. The more or less startling effects of weak prestimulation. , 1975, Psychophysiology.

[44]  Seymour Geisser,et al.  Statistical Principles in Experimental Design , 1963 .

[45]  S. A. Barnett,et al.  Learning and instinct in animals. , 1957 .