Rising COVID-19 related acute pulmonary emboli but falling national chronic thromboembolic pulmonary hypertension referrals from a large national dataset

Chronic thromboembolic pulmonary hypertension (CTEPH) is an uncommon but significant complication of acute pulmonary embolism (PE). There is a strong, documented causal relationship between COVID-19 and venous thromboembolism. Despite this, we have observed a seemingly dichotomous reduction in the rate of new CTEPH referrals during the pandemic to our national specialist centre. Royal Papworth Hospital, Cambridge, is the UK's only quaternary CTEPH centre and captures all new diagnoses.

[1]  M. Humbert,et al.  PH CARE COVID survey: an international patient survey on the care for pulmonary hypertension patients during the early phase of the COVID-19 pandemic , 2021, Orphanet Journal of Rare Diseases.

[2]  M. Newnham,et al.  COVID-19, immunothrombosis and venous thromboembolism: biological mechanisms , 2021, Thorax.

[3]  Gary Alan Bass,et al.  Elective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans , 2020, The British journal of surgery.

[4]  M. Humbert,et al.  2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS): supplementary data , 2019 .

[5]  J. Wild,et al.  The impact of patient choice on survival in chronic thromboembolic pulmonary hypertension , 2018, European Respiratory Journal.

[6]  E. Vicaut,et al.  Impact of Thrombolytic Therapy on the Long-Term Outcome of Intermediate-Risk Pulmonary Embolism. , 2017, Journal of the American College of Cardiology.

[7]  M. Madani,et al.  State-of-the-art chronic thromboembolic pulmonary hypertension diagnosis and management , 2012, European Respiratory Review.

[8]  H. Ghofrani,et al.  Chronic thromboembolic pulmonary hypertension , 2004, European Respiratory Journal.

[9]  K. Kerr,et al.  Chronic thromboembolic pulmonary hypertension. , 2001, Clinics in chest medicine.

[10]  W. Auger,et al.  Chronic thromboembolic pulmonary hypertension. , 2009, Seminars in respiratory and critical care medicine.