Outcomes of an Early Protocol for Dependent Conditioning in Lower Extremity Microsurgical Free Flaps

Background Free tissue transfer is integral to traumatic, oncologic, and diabetic lower limb reconstruction. However, limited data exist on postoperative dependent conditioning or “dangling.” We report our experience utilizing an early pathway for fasciocutaneous flap dangles. Methods Lower extremity microsurgical reconstructions from December 2014 to December 2016 were reviewed. Postoperative pathway included tissue oximetry and Doppler monitoring. On postoperative day 2, dangling started at 5 minutes three times daily with monitoring for flap congestion, signal loss, or persistent oximetry drop. Dangles were increased daily by 5 minutes per dangle to 20 minutes three times daily. Results Twenty‐six patients underwent lower extremity reconstruction and completed an early dangling protocol with anterolateral thigh (n = 23, 88.5%) or medial sural artery perforator (MSAP, n = 3, 11.5%) flaps. Average age and body mass index (BMI) were 53.6 years and 28.6, respectively. Infection (n = 16), trauma (n = 13), exposed hardware (n = 12), and malignancy (n = 3) were common etiologies with most wounds below the knee (n = 23). Flaps were primarily taken on one perforator (n = 17) with an end‐to‐end arterial (n = 18) and two venous (n = 16) anastomoses. With an 8.7‐month follow‐up, partial and complete flap loss rates were each 3.8% (n = 1). Mean hospital stay was 7.9 days (range: 6‐12 days) with 84.6% (n = 22) of patients on ambulatory care with assistance on discharge. Conclusion Lower extremity microsurgical reconstruction can be performed safely and effectively utilizing a standardized postoperative care and dangling pathway. An early, cautious dangle protocol does not increase complications but affords decreased hospital stays and early flap conditioning. In the absence of complicating factors, such as vascular insufficiency, utilizing a defined protocol in these complex patients allows for enhanced, consistent care.

[1]  Kiomars Aganloo,et al.  The free medial sural artery perforator flap: Versatile option for soft tissue reconstruction in small‐to‐moderate size defects of the foot and ankle , 2018, Microsurgery.

[2]  A. Seth,et al.  Super-Thin and Suprafascial Anterolateral Thigh Perforator Flaps for Extremity Reconstruction , 2017, Journal of Reconstructive Microsurgery.

[3]  M. Ninkovic,et al.  Perfusion Controlled Mobilization after Lower Extremity Free Flaps—Pushing the Limits of Time and Intensity , 2016, Journal of Reconstructive Microsurgery.

[4]  Shuzhong Guo,et al.  Reconstruction of Complex Defects of Lower Extremities Using Thinned Free Muscle Flaps , 2016, Aesthetic Plastic Surgery.

[5]  Bernard T. Lee,et al.  Does Increased Experience with Tissue Oximetry Monitoring in Microsurgical Breast Reconstruction Lead to Decreased Flap Loss? The Learning Effect , 2016, Plastic and reconstructive surgery.

[6]  P. M. Vogt,et al.  Does an Early and Aggressive Combined Wrapping and Dangling Procedure Affect the Clinical Outcome of Lower Extremity Free Flaps?—A Randomized Controlled Prospective Study Using Microdialysis Monitoring , 2015, Journal of Reconstructive Microsurgery.

[7]  H. Suh,et al.  A New Plane of Elevation: The Superficial Fascial Plane for Perforator Flap Elevation , 2014, Journal of Reconstructive Microsurgery.

[8]  A. Daigeler,et al.  Changes of Oxygenation and Hemoglobin-Concentration in Lower Extremity Free Flaps during Dangling , 2014, Journal of Reconstructive Microsurgery.

[9]  G. Hallock Medial sural artery perforator free flap: legitimate use as a solution for the ipsilateral distal lower extremity defect. , 2013, Journal of reconstructive microsurgery.

[10]  L. Levin,et al.  A Retrospective Review of Outcomes and Flap Selection in Free Tissue Transfers for Complex Lower Extremity Reconstruction , 2013, Journal of Reconstructive Microsurgery.

[11]  P. Vogt,et al.  Early Start of the Dangling Procedure in Lower Extremity Free Flap Reconstruction does not Affect the Clinical Outcome , 2012, Journal of Reconstructive Microsurgery.

[12]  E. Ridgway,et al.  New insight into an old paradigm: wrapping and dangling with lower-extremity free flaps. , 2010, Journal of reconstructive microsurgery.

[13]  Kai-Ping Chang,et al.  Anatomical basis and versatile application of the free medial sural artery perforator flap for head and neck reconstruction. , 2010, Plastic and reconstructive surgery.

[14]  J. Dayan,et al.  The versatility of the anterolateral thigh flap in lower extremity reconstruction. , 2009, Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V....

[15]  L. L. Pu,et al.  A recommended protocol for the immediate postoperative care of lower extremity free-flap reconstructions. , 2009, Journal of reconstructive microsurgery.

[16]  P. Taub,et al.  A Survey of Microvascular Protocols for Lower Extremity Free Tissue Transfer II: Postoperative Care , 2008, Annals of plastic surgery.

[17]  S. Levin Vascularized Fibula Graft for the Traumatically Induced Long‐Bone Defect , 2006, The Journal of the American Academy of Orthopaedic Surgeons.

[18]  D. Orgill,et al.  Lower Extremity Trauma: Trends in the Management of Soft-Tissue Reconstruction of Open Tibia-Fibula Fractures , 2006, Plastic and reconstructive surgery.

[19]  Daniel H. Stewart,et al.  Microvascular Free Flap Reconstruction in Pediatric Lower Extremity Trauma: A 10-Year Review , 2005, Plastic and reconstructive surgery.

[20]  L. L. Pu,et al.  Reconstruction of Through-and-Through Gunshot Wounds to the Feet with Free Gracilis Muscle Flaps , 2003, Annals of plastic surgery.

[21]  L. Levin,et al.  The orthoplastic approach for management of the severely traumatized foot and ankle. , 2003, The Journal of trauma.

[22]  L. Levin,et al.  Microsurgical Free Flap Transfer to Amputation Sites: Indications and Results , 2002, Annals of plastic surgery.

[23]  S. Jeng,et al.  Free Anterolateral Thigh Flap for Extremity Reconstruction: Clinical Experience and Functional Assessment of Donor Site , 2001, Plastic and reconstructive surgery.

[24]  D A Hidalgo,et al.  A Review of 716 Consecutive Free Flaps for Oncologic Surgical Defects: Refinement in Donor‐Site Selection and Technique , 1998, Plastic and reconstructive surgery.

[25]  W. Lineaweaver,et al.  The serratus anterior free-muscle flap: experience with 100 consecutive cases. , 1990, Plastic and reconstructive surgery.

[26]  Green Tl,et al.  Soft tissue coverage for lower-extremity trauma: current practice and techniques. A review. , 1988 .

[27]  S. Ariyan,et al.  Free Radial Forearm Flap Versatility for the Head and Neck and Lower Extremity , 1986, Journal of reconstructive microsurgery.

[28]  Jones Re,et al.  Primary versus delayed soft tissue coverage for severe open tibial fractures. A comparison of results. , 1983 .

[29]  R. Jones,et al.  Primary versus delayed soft tissue coverage for severe open tibial fractures. A comparison of results. , 1983, Clinical orthopaedics and related research.

[30]  T. Kohno,et al.  Muscle flap with simultaneous mesh skin graft for skin defects of the lower leg. , 1979, The Journal of trauma.

[31]  J. Garrett,et al.  Free groin-flap transfer for skin defects associated with orthopaedic problems of the lower extremity. , 1978, The Journal of bone and joint surgery. American volume.