On the measurement of the mean velocity of blood flow over the cardiac cycle using Doppler ultrasound.

A number of modern duplex scanners now have facilities for determining volumetric blood flow through intact vessels. The methods these machines use to arrive at an answer must presuppose a number of conditions which may not be met in practice. This paper examines the effect that nonuniform insonation of the target blood vessel (using continuous wave or wide-gate pulsed ultrasound) has on the mean velocity, as determined using mean, root mean square (RMS) and maximum frequency processors. It is shown that for a given beam/vessel geometry the error is dependent only on the shape of the mean component of the velocity profile which, depending on the arterial site, may be flat, parabolic or intermediate. Mean processors may overestimate the mean velocity of established flow by up to 33%, but this could be turned to advantage when it is impracticable to insonate a vessel uniformly. Maximum frequency processors are of value when either plug-flow or fully established flow of low pulsatility is present in the target vessel. In the first case the mean flow is the same as the maximum flow, while in the second the mean flow is half the time averaged maximum flow, irrespective of the size and shape of the ultrasound beam. RMS processors are probably best avoided in volumetric flow measurement applications.

[1]  D. Hokanson,et al.  An Echo-Tracking System for Recording Arterial-Wall Motion , 1970, IEEE Transactions on Sonics and Ultrasonics.

[2]  R. Nerem,et al.  Model study of flow in curved and planar arterial bifurcations. , 1982, Cardiovascular research.

[3]  David S. Sumner,et al.  Hemodynamics for surgeons , 1975 .

[4]  Influence of Beam Profile and Degree of Insonation on the CW Doppler Ultrasound Spectrum and Mean Velocity , 1983, IEEE Transactions on Sonics and Ultrasonics.

[5]  R. Cobbold,et al.  Errors and artifacts of Doppler flowmeters and their solution. , 1977, Archives of surgery.

[6]  P. Peronneau,et al.  Flow in the thoracic aorta. , 1979, Cardiovascular research.

[7]  D. Schultz Chapter 9 – Pressure and Flow in Large Arteries , 1972 .

[8]  R. Reneman,et al.  Local Doppler audio spectra in normal and stenosed carotid arteries in man. , 1979, Ultrasound in medicine & biology.

[9]  N. Browse,et al.  A definition of arteriomegaly and the size of arteries supplying the lower limbs , 1983, The British journal of surgery.

[10]  C. Miller,et al.  Transcutaneous measurement of blood velocity profiles and flow. , 1973, Cardiovascular research.

[11]  J. Arndt,et al.  Mechanics of the Aorta in Vivo: A Radiographic Approach , 1971, Circulation research.

[12]  D. A. Mcdonald Blood flow in arteries , 1974 .

[13]  D. Evans,et al.  Changes in Doppler ultrasound sonagrams at varying distances from stenoses. , 1982, Cardiovascular research.

[14]  H. Hsiao,et al.  The velocity profile in the canine ascending aorta and its effects on the accuracy of pulsed Doppler determinations of mean blood velocity. , 1984, Cardiovascular research.

[15]  C Clark,et al.  The propagation of turbulence produced by a stenosis. , 1980, Journal of biomechanics.

[16]  F. M. Greene,et al.  Computer based pattern recognition of carotid arterial disease using pulsed Doppler ultrasound. , 1982, Ultrasound in medicine & biology.

[17]  D. Liepsch,et al.  Measurement and calculations of laminar flow in a ninety degree bifurcation. , 1982, Journal of biomechanics.

[18]  S. Uematsu,et al.  Measurement of carotid blood flow in man and its clinical application. , 1983, Stroke.

[19]  D H Evans,et al.  Some aspects of the relationship between instantaneous volumetric blood flow and continuous wave Doppler ultrasound recordings--III. The calculation of Doppler power spectra from mean velocity waveforms, and the results of processing these spectra with maximum, mean, and RMS frequency processors. , 1982, Ultrasound in medicine & biology.

[20]  H. B. Atabek,et al.  The inlet length for oscillatory flow and its effects on the determination of the rate of flow in arteries. , 1961, Physics in medicine and biology.

[21]  D H Evans,et al.  Some aspects of the relationship between instantaneous volumetric blood flow and continuous wave Doppler ultrasound recordings--I. The effect of ultrasonic beam width on the output of maximum, mean and RMS frequency processors. , 1982, Ultrasound in medicine & biology.

[22]  M. Lunt Accuracy and limitations of the ultrasonic Doppler blood velocimeter and zero crossing detector. , 1975, Ultrasound in medicine & biology.