Noninvasive blood analysis by tissue-modulated NIR Raman spectroscopy

We present tissue modulated Raman spectroscopy as a technique for noninvasively measuring the concentration of blood analytes in vivo. We present preliminary data used to determine the best methods for analyzing our data. These experiments provide additional proof that we are indeed able to obtain the spectra of human blood in vivo and noninvasively. We discuss differences between our spectra and spectra of bulk blood in vitro. We also discuss the variations between individuals and the impact of those variations on our noninvasive blood glucose measurements.

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