SYSTEM SIMULATION FOR MICROFLUIDIC DESIGN AUTOMATION OF LAB-ON-A-CHIP DEVICES

This paper introduces to the fast system simulation approach for droplet-based microfluidics and its validation. Full custom centric design means the integration and functional combination of microfluidic operation units, such as sample droplet generation, dosing or mixing to a complete Lab-on-a-Chip system. Comparable to large scale integration in EDA a fast simulation for droplet-based microfluidic systems is necessary to prevail in the face of their raising complexity by establishing microfluidic design automation. The design process can be greatly enhanced by our fast network simulation that relies on beha vioral models of the basic microfluidic operation units and their combined effect on the overall behavior.