Analysis of human self-reactive antibody repertoires by quantitative immunoblotting.

[1]  S. Lacroix-Desmazes,et al.  Idiopathic Membranous Glomerulonephritis Is Associated with Altered Patterns of Self‐reactive IgM and IgG Antibody Repertoires , 2001, Scandinavian journal of immunology.

[2]  J. Silver,et al.  Positive selection of natural autoreactive B cells. , 1999, Science.

[3]  A. Fischer,et al.  Defective self-reactive antibody repertoire of serum IgM in patients with hyper-IgM syndrome. , 1999, Journal of immunology.

[4]  S. Lacroix-Desmazes,et al.  Selective impairment of serum antibody repertoires toward muscle and thymus antigens in patients with seronegative and seropositive myasthenia gravis , 1998, European journal of immunology.

[5]  A. Coutinho,et al.  Genetic control of natural antibody repertoires: I. IgH, MHC and TCRβ loci , 1998, European journal of immunology.

[6]  S. Avrameas,et al.  Natural polyreactive secretory immunoglobulin A autoantibodies as a possible barrier to infection in humans , 1997, Infection and immunity.

[7]  S. Kaveri,et al.  Analysis of antibody reactivities toward self antigens of IgM of patients with Waldenström's macroglobulinemia. , 1997, International immunology.

[8]  A. Coutinho,et al.  The repertoire of serum IgM in normal mice is largely independent of external antigenic contact , 1997, European journal of immunology.

[9]  A. Coutinho,et al.  Distinguishable Patterns of Connectivity in Serum Immunoglobulins from SLE Patients and Healthy Individuals , 1997, Scandinavian journal of immunology.

[10]  S. Bondada,et al.  CD5-Mediated Negative Regulation of Antigen Receptor-Induced Growth Signals in B-1 B Cells , 1996, Science.

[11]  A. Coutinho,et al.  The Self‐Reactive Antibody Repertoire of Normal Human Serum IgM is Acquired in Early Childhood and Remains Conserved Throughout Life , 1996, Scandinavian journal of immunology.

[12]  A. Coutinho,et al.  Quantitative analysis of multiple V‐region interactions among normal human IgG , 1996, European journal of immunology.

[13]  S. Avrameas,et al.  Differences in the natural autoantibody patterns of patients with schizophrenia and normal individuals. , 1996, Journal of psychiatry & neuroscience : JPN.

[14]  W. Ouwehand,et al.  Molecular characteristics of anti‐self antibody fragments against neutrophil cytoplasmic antigens from human V gene phage display libraries , 1995, Clinical and experimental immunology.

[15]  D. Devine,et al.  Autoreactive T cells in healthy individuals show tolerance in vitro with characteristics similar to but distinct from clonal anergy , 1995, European journal of immunology.

[16]  A. Coutinho,et al.  Analysis of the natural human IgG antibody repertoire: life‐long stability of reactivities towards self antigens contrasts with age‐dependent diversification of reactivities against bacterial antigens , 1995, European journal of immunology.

[17]  A. Coutinho,et al.  Analysis of the normal human IgG antibody repertoire. Evidence that IgG autoantibodies of healthy adults recognize a limited and conserved set of protein antigens in homologous tissues. , 1995, Journal of immunology.

[18]  R. Williams,et al.  Autoreactivity in HIV-1 infection: the role of molecular mimicry. , 1995, Clinical immunology and immunopathology.

[19]  A. Coutinho,et al.  Studies on the T cell dependence of natural IgM and IgG antibody repertoires in adult mice , 1995, European journal of immunology.

[20]  A. Coutinho,et al.  Invariance and restriction toward a limited set of self-antigens characterize neonatal IgM antibody repertoires and prevail in autoreactive repertoires of healthy adults. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[21]  F. Alt,et al.  CD40-deficient mice generated by recombination-activating gene-2-deficient blastocyst complementation. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[22]  R J Armitage,et al.  Humoral immune responses in CD40 ligand-deficient mice , 1994, The Journal of experimental medicine.

[23]  T. Kipps,et al.  Structure-function studies on a polyreactive (natural) autoantibody. Polyreactivity is dependent on somatically generated sequences in the third complementarity-determining region of the antibody heavy chain. , 1994, Journal of immunology.

[24]  C. Barbas,et al.  The nature of the autoimmune antibody repertoire in human immunodeficiency virus type 1 infection. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[25]  F. Kianifard Applied Multivariate Data Analysis: Volume II: Categorical and Multivariate Methods , 1994 .

[26]  H. Ikematsu,et al.  VH and V kappa segment structure of anti-insulin IgG autoantibodies in patients with insulin-dependent diabetes mellitus. Evidence for somatic selection. , 1994, Journal of immunology.

[27]  A. Coutinho,et al.  Global Analysis of Antibody Repertoires. 1. An Immunoblot Method for the Quantitative Screening of a Large Number of Reactivities , 1994, Scandinavian journal of immunology.

[28]  A. Coutinho,et al.  Global analysis of antibody repertoires. II. Evidence for specificity, self‐selection and the immunological “homunculus” of antibodies in normal serum , 1993, European journal of immunology.

[29]  M. Kazatchkine,et al.  Polyreactivity is a Property of Natural and Disease‐Associated Human Autoantibodies , 1993, Scandinavian journal of immunology.

[30]  W. Fanslow,et al.  Human B cell proliferation and Ig secretion induced by recombinant CD40 ligand are modulated by soluble cytokines. , 1993, Journal of immunology.

[31]  S. Kaveri,et al.  Expression and control of the natural autoreactive IgG repertoire in normal human serum , 1993, European journal of immunology.

[32]  D. Ascher,et al.  Determination of the etiology of seroreversals in HIV testing by antibody fingerprinting. , 1993, Journal of acquired immune deficiency syndromes.

[33]  J. Thomas V region diversity in human anti-insulin antibodies. Preferential use of a VHIII gene subset. , 1993, Journal of immunology.

[34]  C. Maliszewski,et al.  Recombinant human CD40 ligand stimulates B cell proliferation and immunoglobulin E secretion , 1992, The Journal of experimental medicine.

[35]  A. M. Poverenny,et al.  Hidden high-avidity anti-DNA antibodies occur in normal human gammaglobulin preparations. , 1992, Immunology letters.

[36]  J. van Es,et al.  Molecular Approaches to the Study of Human B‐Cell and (Auto)antibody Repertoire Generation and Selection , 1992, Immunological reviews.

[37]  K. Rajewsky,et al.  T Cell‐Dependent Antibody Production by Ly‐1 B Cells a , 1992, Annals of the New York Academy of Sciences.

[38]  M. Stenzel-Poore,et al.  Natural auto- and polyreactive antibodies differing from antigen-induced antibodies in the H chain CDR3. , 1991, Journal of immunology.

[39]  F. Varela,et al.  Population dynamics of natural antibodies in normal and autoimmune individuals. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[40]  T. Ternynck,et al.  IgG autoantibody activity in normal mouse serum is controlled by IgM. , 1990, Journal of immunology.

[41]  T. Ternynck,et al.  Idiotypic interactions between normal human polyspecific IgG and natural IgM antibodies , 1990, European journal of immunology.

[42]  T. Ternynck,et al.  Comparison between autoantibodies arising during Trypanosoma cruzi infection in mice and natural autoantibodies. , 1990, Journal of immunology.

[43]  S. Avrameas,et al.  Natural autoantibodies in nude and normal outbred (Swiss) and inbred (BALB/c) mice. , 1989, Journal of autoimmunity.

[44]  T. Ternynck,et al.  Two murine natural polyreactive autoantibodies are encoded by nonmutated germ-line genes. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[45]  D. Stott,et al.  Immunoblotting and dot blotting , 1989, Journal of Immunological Methods.

[46]  M. Takei,et al.  VH sequence of a human anti-Sm autoantibody. Evidence that autoantibodies can be unmutated copies of germline genes. , 1989, Journal of immunology.

[47]  P. Pereira,et al.  T cell dependence of the “natural” autoreactive B cell activation in the spleen of normal mice , 1988, European journal of immunology.

[48]  A. Francoeur Antibody Fingerprinting: A Novel Method for Identifying Individual People and Animals , 1988, Bio/Technology.

[49]  S. Avrameas,et al.  Polyspecific natural antibodies and autoantibodies secreted by human lymphocytes immortalized with Epstein-Barr virus. , 1988, Blood.

[50]  S. Avrameas,et al.  Single Lipopolysaccharide‐Reactive B Cells in the Non‐Immune Mouse Spleen Cell Population Secrete Natural Multispecific Autoantibodies , 1987, Scandinavian journal of immunology.

[51]  J. Kearney,et al.  Idiotype‐Directed Interactions during Ontogeny Play a Major Role in the Establishment of the Adult B Cell Repertoire , 1986, Immunological reviews.

[52]  S. Avrameas,et al.  Murine Natural Monoclonal Autoantibodies: A Study of their Polyspecificities and their Affinities , 1986, Immunological reviews.

[53]  A. Coutinho,et al.  High frequency of natural autoantibodies in normal newborn mice. , 1985, Journal of immunology.

[54]  H. Towbin,et al.  Immunoblotting and dot immunobinding--current status and outlook. , 1984, Journal of immunological methods.

[55]  R. Hardy,et al.  Ly-1 B cells: functionally distinct lymphocytes that secrete IgM autoantibodies. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[56]  S. Avrameas,et al.  Murine hybridomas secreting natural monoclonal antibodies reacting with self antigens. , 1983, Journal of immunology.

[57]  S. Avrameas,et al.  Studies on natural antibodies and autoantibodies. , 1983, Annales d'immunologie.

[58]  S. Avrameas,et al.  Studies on natural antibodiesand autoantibodies , 1983 .

[59]  R. Hardy,et al.  The "Ly-1 B" cell subpopulation in normal immunodefective, and autoimmune mice , 1983, The Journal of experimental medicine.

[60]  S. Avrameas,et al.  Naturally occurring antibodies against nine common antigens in human sera. I. Detection, isolation and characterization. , 1982, Journal of immunology.

[61]  S. Kaveri,et al.  Altered control of self-reactive IgG by autologous IgM in patients with warm autoimmune hemolytic anemia. , 2000, Blood.

[62]  B. Stockinger T lymphocyte tolerance: from thymic deletion to peripheral control mechanisms. , 1999, Advances in immunology.

[63]  M. Cooke,et al.  Self-tolerance checkpoints in B lymphocyte development. , 1995, Advances in immunology.

[64]  M. Kazatchkine,et al.  Cellular and molecular aspects of systemic autoimmunity , 1993 .

[65]  A. Coutinho,et al.  Autoimmunity : physiology and disease , 1993 .

[66]  F. Varela,et al.  Second generation immune networks. , 1991, Immunology today.

[67]  S. Avrameas Natural autoantibodies: from 'horror autotoxicus' to 'gnothi seauton'. , 1991, Immunology today.

[68]  M. Clanet,et al.  Comparative study of natural autoantibodies in the serum and cerebrospinal fluid of normal individuals and patients with multiple sclerosis and other neurological diseases. , 1988, Annales de l'Institut Pasteur. Immunology.

[69]  Robbert Benner,et al.  Isotypes and specificities of immunoglobulins produced by germ‐free mice fed chemically defined ultrafiltered “antigen‐free” diet , 1984, European journal of immunology.