Serotonin and Octopamine Produce Opposite Postures in Lobsters

Serotonin and octopamine, injected into the circulation of freely moving lobsters and crayfish, produce opposite behavioral effects. Octopamine injection produces sustained extension of the limbs and abdomen; serotonin injection produces sustained flexion. Neurophysiological analyses show that these postures can be accounted for by opposing, coordinated effects of these amines on patterns of motoneuron activity recorded from the ventral nerve cord.

[1]  W. H. Evoy,et al.  Release of Coordinated Behavior in Crayfish by Single Central Neurons , 1966, Science.

[2]  D. Potter,et al.  Physiological and chemical architecture of a lobster ganglion with particular reference to gamma-aminobutyrate and glutamate. , 1967, Journal of neurophysiology.

[3]  W. H. Evoy,et al.  The central nervous organization underlying control of antagonistic muscles in the crayfish. II. Coding of position by command fibers , 1967 .

[4]  W. H. Evoy,et al.  The central nervous organization underlying control of antagonistic muscles in the crayfish. I. types of command fibers , 1967 .

[5]  P. Molinoff,et al.  An enzymatic assay for octopamine and other beta-hydroxylated phenylethylamines. , 1969, The Journal of pharmacology and experimental therapeutics.

[6]  A. Selverston,et al.  Neural geometry and activation of crayfish fast flexor motoneurons. , 1972, Journal of neurophysiology.

[7]  S. Grillner,et al.  The locomotion of the acute spinal cat injected with clonidine i.v. , 1973, Brain research.

[8]  James L. Larimer,et al.  Command Fibres in the Circumoesophageal Connectives of Crayfish , 1974 .

[9]  E. Kravitz,et al.  Octopamine neurons: morphology, release of octopamine and possible physiological role , 1975, Brain Research.

[10]  Analysis of postural motoneuron activity in crayfish abdomen. I. Coordination by premotoneuron connections. , 1975, Journal of neurophysiology.

[11]  W G Tatton,et al.  Analysis of postural motoneuron activity in crayfish abdomen. II. Coordination by excitatory and inhibitory connections between motoneurons. , 1975, Journal of neurophysiology.

[12]  E. Kravitz,et al.  The association of octopamine with specific neurones along lobster nerve trunks. , 1976, The Journal of physiology.

[13]  E. Kravitz,et al.  Octopamine release at two points along lobster nerve trunks. , 1976, The Journal of physiology.

[14]  M. S. Berry,et al.  Properties of a symmetric pair of serotonin-containing neurones in the cerebral ganglia of Planorbis. , 1976, The Journal of experimental biology.

[15]  E. Kravitz,et al.  Targets of octopamine action in the lobster: cyclic nucleotide changes and physiological effects in hemolymph, heart and exoskeletal muscle. , 1978, The Journal of pharmacology and experimental therapeutics.

[16]  I. Kupfermann,et al.  Modulatory control of buccal musculature by a serotonergic neuron (metacerebral cell) in Aplysia. , 1978, Journal of neurophysiology.